Retention capacity of topical imidazole antifungal agents in the skin

International Journal of Pharmaceutics

Volumn 161, Issue 2, 1998, Pages 195-204

  Hashiguchi, Terushi ^a   Kodama, Ai ^a   Ryu, Akie ^a   Otagiri, Masaki ^b  

^a HISAMITSU PHARMACEUTICAL CO INC   (Japan)

^b Fac Pharmaceutical Sci   (Japan)

Author keywords

Binding; Diffusion energy; Fourier transform infrared; Keratin; Omoconazole; Retention capacity

Indexed keywords

ANTIFUNGAL AGENT; BIFONAZOLE; CLOTRIMAZOLE; KERATIN; OMOCONAZOLE;

ADSORPTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG PROTEIN BINDING; DRUG TISSUE LEVEL; FEMALE; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; LIPOPHILICITY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SKIN; SKIN PENETRATION; STRATUM CORNEUM;

EID: 0032559578     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00352-9     Document Type: Article

References (28)

1. Arika T., Hase T., Yokoo M. Activity of topical antifungals on infected sites - skin permeability and adsorption to horny materials. Nishinihon J. Dermatol. 52:1990;545-549.
2. Baker J.R.J., Christian R.A., Simpson P., White A.M. The binding of topically applied glucocorticoids to rat skin. Br. J. Dermatol. 96:1977;171-178.
3. Blank I.H. Factors which influence the water content of the stratum corneum. J. Invest. Derm. 18:1952;433-440.
4. Bottari F., Dicolco G., Nannipieri E., Saetonne M.F., Serafini M.F. Influence of drug concentration on 'in vitro' release of salicylic acid from ointment base. J. Pharm. Sci. 63:1974;1779-1783.
5. Büchel K.H., Draber W., Regel E., Plempel M. Synthesen und Eigenschaften von Clotrimazol und weiteren antimykotischen 1-Triphenylmethylimidazolen. Arzneim.-Forsch. Drug Res. 22:1972;1260-1272.
6. Freedman M.H., Baxter R.M., Waker G.C. In vitro sorption of Griseofulvin by keratin substrates. J. Invest. Dermatol. 38:1962;199-208.
7. Gummer C.L., Hinz R.S., Maibach H.I. The skin penetration: a design update. Int. J. Pharm. 40:1987;101-104.
8. Haneke E. Retention of Ketoconazole in the skin following oral treatment. Hautarzt. 38(2):1987;93-96.
9. Higuchi T. Physical chemical analysis of percutaneous absorption process from creams and ointments. J. Soc. Cosmet. Chem. 11:1960;85-97.
10. Itoyama T., Aoki Y., Hiratani T., Uchida K., Yamaguchi H. In vitro antifungal activity of Omoconazole nitrate, a new imidazole antimycotic. Jpn. J. Antibiot. 46:1993;773-780.
11. Komatsu H., Okamoto H., Miyagawa K., Hashida M., Sezaki H. Percutaneous absorption of butylparaben from liposomes in vitro. Chem. Pharm. Bull. 34:1986;3423-3430.
12. Loftsson T., Bodor N. Improved delivery through biological membranes X: percutaneous absorption and metabolism of methylsulfinylmethyl2- acetoxybenzoate and related aspirin prodrugs. J. Pharm. Sci. 70:1981;756-758.
13. Lüker P.W., Beubler E., Kukovetz W.R., Ritter W. Retention time and concentration in human skin of Bifonazole and Clotrimazole. Dermatologica. 169:1984;51-56.
14. Manako T., Miyata S., Aoki T., Kodama A., Yamakawa H. Chemical structure, Physico- chemical properties and stability of Omoconazole nitrate. Iyakuhin Kenkyu. 28(4):1997;251-263.
15. Niwano Y., Kuzuhara N., Kanai K., Hamaguchi H. In vitro antifungal activity of Lanoconazole, a topical antifungal agent. Clinical Report. 30(1):1996;123-130.
16. 14C]Bifonazole in man. Arzneim.-Forsch. Drug Res. 33(1):1983;745-750.
17. Sasaki H., Takahashi T., Mori Y., Nakamura J., Shibasaki J. Transdermal delivery of 5-fluorouracil and its alkylcarbamoyl derivatives. Int. J. Pharm. 60:1990;1-9.
18. Schaefer H., Stüttgen G. Absolute concentrations of an antimycotic agent, Econazole, in the human skin after local application. Arzneim.-Forsch. Drug Res. 26:1976;432-435.
19. Stüttgen G. Promoting penetration of locally applied substances by urea. Hautarzt. 40(9):1989;27-31.
20. Takahashi H. Some aspects of topical antifungal agents. Jpn. J. Dermatol. 82:1972;421-437.
21. Takahashi H. Some problems in topical antifungals. Biomed. Ther. 20:1988;435-439.
22. Takahashi H. Problems with the topical antimycotics. Jpn. J. Med. Mycol. 35:1994;331-334.
23. Takahashi Y., Tamura H., Shioyama C., Funaba T., Hayashi T. Physico-chemical properties and stability of Bifonazole (BAYh 4502). Iyakuhin Kenkyu. 15:1984;438-447.
24. Tomura A., Takahashi S. Experimental study on pharmacodynamic action of topical antifungal agents in the human stratum corneum. Jpn. J. Med. Mycol. 36:1995;149-156.
25. Uchida K., Yamaguchi H. Studies on the affinity of Terbinafine with keratin. Jpn. J. Med. Mycol. 34:1993;207-212.
26. Vickers C.F.H. Existence of reservoir in the stratum corneum. Arch. Dermatol. 88:1963;72-75.
27. Walter K., Kurz H. Binding of drugs to human skin: influencing factors and the role of tissue lipids. J. Pharm. Pharmacol. 40:1988;689-693.
28. Zirngibl L., Fischer J., Jahn U., Thiele K. Structure-activity relationships of 2-(1H-imidazol-1-y1)vinyl esters. Ann. New York Acad. Sci. 544:1988;63-73.