Vehicle-dependent in situ modification of membrane-controlled drug release

Journal of Controlled Release

Volumn 51, Issue 1, 1998, Pages 23-34

  Imanidis, G ^a   Helbing Strausak, S ^a   Imboden, R ^a   Leuenberger, H ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Membrane controlled release; Membrane vehicle interaction; Polypropylene membrane

Indexed keywords

DRUG CARRIER; DRUG VEHICLE; POLYPROPYLENE;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUTION; KINETICS; MEMBRANE; MEMBRANE TRANSPORT; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; VISCOSITY;

ANTI-INFLAMMATORY AGENTS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG DELIVERY SYSTEMS; KINETICS; MATHEMATICAL COMPUTING; MEMBRANES, ARTIFICIAL; MODELS, CHEMICAL; PERMEABILITY; POLYPROPYLENES; SALICYLIC ACID; SALICYLIC ACIDS; VEHICLES;

EID: 0032559305     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00125-9     Document Type: Article

References (16)

1. J. Heller, Use of polymers in controlled release of active agents, in: J.R. Robinson, V.H.L. Lee (Eds.), Controlled Drug Delivery-Fundamentals and Applications, Marcel Dekker, Inc., New York and Basel, 1987, pp. 179-212.
2. J.W. Dohner, Development of processes and equipment for rate-controlled transdermal therapeutic systems, in: Y.W. Chien (Ed.), Transdermal Controlled Systemic Medications, Marcel Dekker, Inc., New York and Basel, 1987, pp. 349-364.
3. Chen S.X., Lostritto R.T. Diffusion of benzocaine in poly(ethylene-vinyl acetate) membranes: Effects of vehicle ethanol concentration and membrane vinyl acetate content. J. Control. Release. 38:1996;185-191.
4. Pokharkar V.B., Sivaram S. Permeability studies across poly(alkylene carbonate) membranes. J. Control. Release. 41:1996;157-162.
5. G.C. Ritthidej, W. Leesajakul, Chitosan as rate-controlling membrane in isosorbide dinitrate transdermal patch, in: Proceedings of the 23rd International Symposium on Controlled Release Bioactive Materials, 1996, pp. 202-203.
6. Miyajima M., Okano T., Kim S.W., Higuchi W.I. Preformulation of an Ara-A transdermal delivery system: Membrane fabrication and characterization. J. Control. Release. 5:1987;179-186.
7. Comfort A.R., Shevchuk I., Otte J.H., Dinh S.M. In vitro characterization of a solvent-controlled nitroglycerin transdermal system. J. Control. Release. 34:1995;193-201.
8. A.C. Watkinson, H. Joubin, D.M. Green, K.R. Brain, J. Hadgraft, Vehicle/membrane interactions in permeability studies, in: Proceedings of the 22nd International Symposium on Controlled Release Bioactive Materials, 1995, pp. 642-643.
9. Merkle H.P., Knoch A., Gienger G. Release kinetics of polymeric laminates for transdermal delivery: Experimental evaluation and physical modeling. J. Control. Release. 2:1985;99-110.
10. ® microporous membranes. J. Membr. Sci. 15:1983;97-113.
11. Celgard® 2500 Data Sheet, Hoechst Celanese Corp.
12. J. Crank. The Mathematics of Diffusion. Oxford University Press, Oxford, 1975, pp. 35-37.
13. Paul D.R., McSpadden S.K. Diffusional release of a solute from a polymer matrix. J. Membr. Sci. 1:1976;33-48.
14. J. Crank. The Mathematics of Diffusion. Oxford University Press, Oxford, 1975, pp. 60-61.
15. Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspension. J. Pharm. Sci. 50:1961;874-875.
16. Roseman T.J., Higuchi W.I. Release of medroxyprogesterone acetate from a silicone polymer. J. Pharm. Sci. 59:1970;353-357.