A new and novel amide bond cleavage of N-methoxymethylpyrrolo[2,1- c][1,4]benzodiazepine-5,11-diones by hydride reduction via 3-aza-Grob fragmentation

Tetrahedron

Volumn 54, Issue 43, 1998, Pages 13149-13154

  Wang, Jeh Jeng ^a   Hu, Wan Ping ^a   Chung, Hung Wei ^a   Wang, Li Fang ^a   Hsu, Mei Hui ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE;

ARTICLE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REDUCTION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

EID: 0032558627     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)00795-9     Document Type: Article

References (20)

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12. max = 50.1°. 1446 reflections measured, 932 observed reflections (I>3.00σ(I)), residuals: R = 0.058, Rw = 0.031. The unit-cell parameters were determined by a least-aquares refinement on diffractometer angles for 24 (17.52-27.00°) automatically centred reflections. The crystal structure was solved by directed methods. Atomic parameters, bond lengths, bonds angles and torsion angles have been deposited at the Cambridge Crystallographic Data Center.
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