Restriction of 480/270-kD ankyrin(G) to axon proximal segments requires multiple ankyrin(G)-specific domains

Journal of Cell Biology

Volumn 142, Issue 6, 1998, Pages 1571-1581

  Zhang, Xu ^a   Bennett, Vann ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Ankyrin; Axon initial segment; Cell polarity; Membrane dynamics; Spectrin

Indexed keywords

ANKYRIN; SPECTRIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL POLARITY; DORSAL ROOT; IMMUNOFLUORESCENCE; KNOCKOUT MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; ANKYRINS; AXONS; BINDING SITES; CELL ADHESION MOLECULES; CELL MEMBRANE; CELLS, CULTURED; CHICKENS; GANGLIA, SPINAL; HUMANS; NERVE GROWTH FACTORS; NEURONS; RABBITS; RATS; SERINE; SPECTRIN;

EID: 0032555941     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.6.1571     Document Type: Article

References (41)

1. Bennett, V. 1978. Purification of an active proteolytic fragment of the membrane attachment site for human erythrocyte spectrin. J. Biol. Chem. 253: 2292-2299.
2. Bennett, V. 1990. Spectrin-based membrane skeleton: a multipotential adaptor between plasma membrane and cytoplasm. Physiol. Rev. 70:1029-1065.
3. Bennett, V., and J. Davis. 1981. Erythrocyte ankyrin: immunoreactive analogues are associated with mitotic structures in cultured cells and with microtubules in brain. Proc. Natl. Acad. Sci. USA. 78:7550-7554.
4. Bennett, V., and D.M. Gilligan. 1993. The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane. Annu. Rev. Cell Biol. 9:27-66.
5. Bennett, V., S. Lambert, J.Q. Davis, and X. Zhang. 1997. Molecular architecture of the specialized axonal membrane at the node of Ranvier. Soc. Gen. Physiol. Ser. 52:107-120.
6. Chan, W., E. Kordeli, and V. Bennett. 1993. 440-kD ankyrin-B: structure of the major developmentally regulated domain and selective localization in unmyelinated axons. J. Cell Biol. 123:1463-1473.
7. Davis, J.Q., and V. Bennett. 1983. Brain spectrin. Isolation of subunits and formation of hybrids with erythrocyte spectrin subunits. J. Biol. Chem. 258: 7757-7766.
8. r spectrin-binding domain. J. Biol. Chem. 259:1874-1881.
9. Davis, J.Q., and V. Bennett. 1984b. Brain ankyrin. A membrane-associated protein with binding sites for spectrin, tubulin, and the cytoplasmic domain of the erythrocyte anion channel. J. Biol. Chem. 259:13550-13559.
10. Davis, J.Q., and V. Bennett. 1990. The anion exchanger and Na+K(+)-ATPase interact with distinct sites on ankyrin in in vitro assays. J. Biol. Chem. 265: 17252-17256.
11. Davis, J.Q., T. McLaughlin, and V. Bennett. 1993. Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. J. Cell Biol. 232:121-133.
12. Davis, J.O., and V. Bennett. 1994. Ankyrin-binding activity shared by the neurofascin/L1/NrCam family of nervous system cell adhesion molecules. J. Biol. Chem. 269:27163-27166.
13. Davis, J., S. Lambert, and V. Bennett. 1996. Molecular composition of the node of Ranvier: Identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAm at nodal axon segments. J. Cell Biol. 135:1355-1367.
14. Deerinck, T.J., S.R. Levinson, G.V. Bennett, and M.H. Ellisman. 1997. Clustering of voltage-sensitive sodium channels on axons is independent of direct Schwann cell contact in the dystrophic mouse. J. Neurosci. 17:5080-5088.
15. Dugandzija-Novakovic, S., A.G. Koszowski, S.R. Levinson, and P. Shrager. 1995. Clustering of Na+ channels and node of Ranvier formation in remyelinating axons. J. Neurosci. 15:492-503.
16. Flucher, B., and M. Daniels. 1989. Membrane proteins in the neuromuscular junction. Distribution of Na channels and ankyrin is complementary to acetylcholine receptors and the 43-kD protein. Neuron. 3:163-175.
17. Garver, T., J. Davis, Q. Ren, S. Tuvia, and V. Bennett. 1997. Tyrosin phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J. Cell Biol. 137:703-714.
18. Howe, C.L., L.M. Sacramone, M.S. Mooseker, and J.S. Morrow. 1985. Mechanisms of cytoskeletal regulation: modulation of membrane affinity in avian brush border and erythrocyte spectrins. J. Cell Biol. 101:1379-1385.
19. Hsieh, S.T., G.J. Kidd, T.O. Crawford, Z. Xu, W.M. Lin, B.D. Trapp, D.W. Cleveland, and J.W. Griffin. 1994. Regional modulation of neurofilament organization by myelination in normal axons. J. Neurosci. 14:6392-6401.
20. Hu, R.J., S. Moorthy, and V. Bennett. 1995. Expression of functional domains of beta G-spectrin disrupts epithelial morphology in cultured cells. J. Cell Biol. 128:1069-1080.
21. Jacobson, K., A. Ishihara, and R. Inman. 1987. Lateral diffusion of proteins in membrane. Annu. Rev. Physiol. 49:163-175.
22. Jacobson, K., E.D. Sheets, and R. Simson. 1995. Revisiting the fluid mosaic model of membranes. Science. 268:1441-1442.
23. Kaplan, M.R., A. Meyer-Franke, S. Lambert, V. Bennett, I.D. Duncan, S.R. Levinson, and B.A. Barres. 1997. Induction of sodium channel clustering by oligodendrocytes. Nature. 386:724-728.
24. Kleitman, N., P. Wood, and K.P. Bunge. 1991. Tissue culture methods for the study of myelination. In Culturing Nerve Cells. G. Banker and K. Goslin, editors. The MIT Press, Cambridge, MA. 337-377.
25. Kordeli, E., J. Davis, B. Trapp, and V. Bennett. 1990. An isoform of ankyrin is localized at nodes of Ranvier in myelinated axons of central and peripheral nerves. J. Cell Biol. 110:1341-1352.
26. G: a new ankyrin gene with neural-specific isoforms localized at the axonal proximal segment and node of Ranvier. J. Biol. Chem. 270:2352-2359.
27. Kusumi, A., Y. Sako, and M. Yamamoto. 1993. Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells. Biophys. J. 65:2021-2040.
28. Lambert, S., J.Q. Davis, and V. Bennett. 1997. Morphogenesis of the node of Ranvier: co-clusters of ankyrin and ankyrin-binding integral proteins define early developmental intermediates. J. Neurosci. 17:7025-7036.
29. Michaely, P., and V. Bennett. 1995a. The ANK repeats of erythrocyte ankyrin form two distinct but cooperative binding sites for the erythrocyte anion exchanger. J. Biol. Chem. 270:22050-22057.
30. 3 anion exchanger. J. Chem. 270:31298-31302.
31. Peters, L.L., K.M. John, F.M. Lu, E.M. Eicher, A. Higgins, M. Yialamas, L.C. Turtzo, A. Otsuka, and S.E. Lux. 1995. Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain. J. Cell Biol. 130:313-321.
32. Salzer, J.L. 1997. Clustering sodium channels at the node of Ranvier: close encounters of the axon-glia kind. Neuron. 18:843-846.
33. Srinivasan, Y., L. Elmer, J. Davis, V. Bennett, and K. Angelides. 1988. Ankyrin and spectrin associate with voltage-dependent sodium channels in brain. Nature. 333:177-180.
34. Vabnick, I., S.D. Novakovic, S.R. Levinson, M. Schachner, and P. Shrager. 1996. The clustering of axonal sodium channels during development of the peripheral nervous system. J. Neurosci. 16:4914-4922.
35. Vabnick, I., A. Messing, S.Y. Chiu, S.R. Levinson, M. Schachner, J. Roder, C. Li, S. Novakovic, and P. Shrager. 1997. Sodium channel distribution in axons of hypomyelinated and MAG null mutant mice. J. Neurosci. Res. 50:321-336.
36. Waxman, S.G. 1984. Nodelike membrane at extranodal sites: comparative morphology and physiology. In The Node of Ranvier. J.C. Zagoren and S. Fedoroff, editors. Academic Press, Inc. Orlando, FL. 311-351.
37. G at the adult rat neuromuscular junction. J. Cell Biol. 140:675-684.
38. Zhang, F., B. Crise, B. Su, Y. Hou, J.K. Rose, A. Bothwell, and K. Jacobson. 1991. Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins. J. Cell Biol. 115:75-84.
39. G isoforms targeted to nodes of Ranvier. J. Biol. Chem. 271:31391-31398.
40. G and its interaction with neurofascin. Ph.D. thesis. Duke University, Durham, NC. 132-162.
41. Zhang, X., J. Davis, S. Carpenter, and V. Bennett. 1998. Structural requirements for association of neurofascin with ankyrin. J. Biol. Chem. 273:In press.