Deracemization of compounds possessing a sec-alcohol or -amino group through a cyclic oxidation-reduction sequence: A kinetic treatment

Tetrahedron Asymmetry

Volumn 9, Issue 16, 1998, Pages 2901-2913

  Kroutil, Wolfgang ^a   Faber, Kurt ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; AMINE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CHIRALITY; COMPUTER ANALYSIS; COMPUTER PROGRAM; COMPUTER SIMULATION; ENANTIOMER; MATHEMATICAL COMPUTING; OXIDATION REDUCTION REACTION; PARAMETER; PRIORITY JOURNAL; RACEMIC MIXTURE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0032555561     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00306-1     Document Type: Article

References (52)

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30. This can be conveniently explained by different paths of various gradient leading to a hilltop, the gradient determines the length of each path to reach the top.
31. The term 'theoretical turnover' indicates the theoretical equivalents of reagents needed if oxidation and reduction are considered as 'ideal' reactions. In practice, however, the amounts required will be larger because excess reagent(s) may be needed in order to drive the reaction towards completion and/or due to decomposition of reagents during undesired side reactions.
32. Alternatively, the Poe-scale can be used. The Poe-value corresponding to a time-value can be easily calculated through the e.e. at a given point of the reaction.
33. Kroutil, W.; Faber, K. (© 1998). 'Cyclo' is a free shareware program run through Windows. The program is available via the Internet at http://www-orgc.tu-graz.ac.at or directly from the authors. A description of how to use the program is given in the help-file which accompanies the program.
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38. 2+ or non-heme iron are involved.
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