Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: A new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 14, 1998, Pages 1913-1918

  Ogawa, Akira ^a   Shuto, Satoshi ^a   Inanami, Osamu ^b   Kuwabara, Mikinori ^b   Tanaka, Motohiro ^c   Sasaki, Takuma ^c   Matsuda, Akira ^a  

^a Grad Sch Pharmaceutical Sci   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

Antiproliferative Agent; DNA; Nucleosides

Indexed keywords

2' DEOXY 2' HYDROXYLAMINOCYTIDINE; 2' DEOXY 2' HYDROXYLAMINOURIDINE; HYDROXYLAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG DESIGN; DRUG SYNTHESIS; MOUSE; NONHUMAN; PHOSPHORYLATION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; DEOXYCYTIDINE; DEOXYURIDINE; DNA REPLICATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROXYLAMINES; MICE; PHOSPHORYLATION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032555110     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00336-9     Document Type: Article

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