"Symmetry" in the synthesis of the A-ring of a vitamin D hybrid analogue with significant transactivation activity: A combinatorial sequence of regioselective propiolate-ene, catalytic enantioselective epoxidation and carbonyl-ene cyclization reactions

Tetrahedron Letters

Volumn 39, Issue 21, 1998, Pages 3359-3362

  Mikami, Koichi ^a   Osawa, Ayako ^a   Isaka, Akira ^a   Sawa, Eiji ^a   Shimizu, Masaki ^a   Terada, Masahiro ^a   Kubodera, Noboru ^b   Nakagawa, Kimie ^c   Tsugawa, Naoko ^c   Okano, Toshio ^c  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D DERIVATIVE;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; ENANTIOMER; EPOXIDATION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

EID: 0032555010     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00272-X     Document Type: Article

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