Effect of temazepam on oxygen saturation and sleep quality at high altitude: Randomised placebo controlled crossover trial

British Medical Journal

Volumn 316, Issue 7131, 1998, Pages 587-589

  Dubowitz, Gerald ^a,b  

^a British Mount Everest Medical Expedition   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR STIMULATING AGENT; TEMAZEPAM;

ADULT; ALTITUDE; ARTERIAL OXYGEN SATURATION; ARTICLE; BREATHING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CROSSOVER PROCEDURE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP;

EID: 0032554308     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.316.7131.587     Document Type: Article

References (14)

1. Barcroft J. The respiratory function of die blood, part 2. Lessons from high altitude. Cambridge: Cambridge University Press, 1923.
2. Ravcnhill TU. Some experiences of mountain sickness in the Andes, J Trop Med Hyg 1913;16:313-20.
3. Anholm JD, Powles AC, Downey R, Houston CS, Sutton JR. Bonnet MH, et al. Operation Everest. II. Arterial oxygen saturation during sleep at extreme altitude. Am Rev Respir Dis 1992:145:817-26.
4. Weil JV. Sleep at high altitude, din Chest Med 19S5;G:615-21.
5. Reite M, Jackson D, Cahoon RI, Weil JV. Sleep physiology at high altitude. Electroenerphalogr Clin Xeuophjdol 1975;38:463-71.
6. West JB, Peters RM, Aksnes C, Marek KH, MillJS, Shoene RB. Nocturnal periodic breathing at altitudes of 6300 m and 8050 m. J Appl Physiol 1986;61:280-7.
7. Goldenberg F, Richalet JP, Onnen I, Antezana AM. Sleep apneas and high altitude newcomers. IntJ Sports Med 1992;13:S34-G.
8. Bonnet MH, DexterJR, Arand DL. The effect of triazolani on arousal and respiration in central sleep apnoea patients. Sleep 1990;13:31-41.
9. Bonnet MH. Performance and sleepiness follouing moderate sleep disruption and slow wave sleep deprivation. Plystol Behav 19SG;37:915-8.
10. Xicholson AN, Smith PA, Stone BM, BradwcII AR, CooteJH. Altitude insomnia: studies during an expedition to the Himalaya. Slffp 1988;11354-61.
11. Laserre E. Insomnies d'altitude: efficacité du fluritrazepam. [High altitude insomnia: efficacy of fluritrazepam.] t\onv Presse Med 1979;8:2577-8.
12. Goldenberg F, Richalet JP.Jouhandin M, Gisquet A, Keromes A, Larmignat P. Respiration periodique pendant le sommeil en altitude. Effets d'une benzodiazepine hypnotique, le loprazolam. [Periodic respiration during sleep at high altitude. Effect of a benzodiazepine hypnotic, loprazolam.] Presse Med 1988;17:1-4.
13. Sutton JR, Gray GW, Houston CS, Powles ACP. Effects of acclimatization on sleep hypoxaemia at altitude. In: West JB, Lahiri S, eds. High altitude and man. Washington, DC: American Physiological Society, 1983.
14. Powles SCP, Sutton JR. Sleep at Altitude. Setnin Resp Med 19S3;5:175-80.