Tick bites and lyme disease in an endemic: Setting problematic use of serologic testing and prophylactic antibiotic therapy

JAMA

Volumn 279, Issue 3, 1998, Pages 206-210

  Fix, Alan D ^a   Strickland, G Thomas ^a   Grant, John ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Kent County Health Department   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CEFADROXIL; CIPROFLOXACIN; CLARITHROMYCIN; CLAVULANIC ACID; DOXYCYCLINE;

ANTIBIOTIC THERAPY; ARTICLE; COUNSELING; DRUG EFFICACY; ENDEMIC DISEASE; HUMAN; LYME DISEASE; PRIORITY JOURNAL; PROPHYLAXIS; SEROCONVERSION; SEROLOGY; TICK BITE;

EID: 0032554140     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.279.3.206     Document Type: Article

References (36)

1. Lyme disease - United States, 1991-1992. MMWR Morb Mortal Wkly Rep. 1993;42:345-348.
2. Costello CM, Steere AC, Pinkerton RE, Feder HM Jr. A prospective study of tick bites in an endemic area for Lyme disease. J Infect Dis. 1989;159: 136-139.
3. Shapiro ED, Gerber MA, Holabird NB, et al. A controlled trial of antimicrobial prophylaxis for Lyme disease after deer-tick bites. N Engl J Med. 1992;327:1769-1773.
4. Agre F, Schwartz R. The value of early treatment of deer tick bites for the prevention of Lyme disease. AJDC. 1993;147:945-947.
5. Warshafsky S, Nowakowski J, Nadelman RB, Kamer RS, Peterson SJ, Wormser GP. Efficacy of antibiotic prophylaxis for prevention of Lyme disease. J Gen Intern Med. 1996;11:329-333.
6. Eppes SC, Klein JD, Caputo GM, Rose CD. Physician beliefs, attitudes, and approaches toward Lyme disease in an endemic area. Clin Pediatr. 1994; 33:130-134.
7. Coyle BS, Strickland GT, Liang YY, Pena C, McCarter R, Israel E. The public health impact of Lyme disease in Maryland. J Infect Dis. 1996;173: 1260-1262.
8. Ziska MH, Donta ST, Demarest FC. Physician preferences in the diagnosis and treatment of Lyme disease in the United States. Infection. 1996;4:182-186.
9. Bakken LL, Case KL, Callister SM, Bourdeau NJ, Schell RF. Performance of 45 laboratories participating in a proficiency testing program for Lyme disease serology. JAMA. 1992;268:891-895.
10. Gerber MA, Bieluch V, Levitz RE, Parry MF, Sabetta J, Schleiter G. Appropriateness of serologic tests and parenteral antibiotic therapy for patients with presumed Lyme disease. Conn Med. 1995;59: 195-196.
11. Craven RB, Quan TJ, Bailey RE, et al. Improved serodiagnostic testing for Lyme disease: results of a multicenter serologic evaluation. Emerg Infect Dis. 1996;2:136-140.
12. Ley C, Le C, Olshen EM, Reingold AL. The use of serologic tests for Lyme disease in a prepaid health plan in California. JAMA 1994;271:460-463.
13. Nachamkin I, Riddle DL, Feldman M, Edelstein PH. Utilization of tests for Lyme disease antibody at a university hospital. Clin Diagn Lab Immunol. 1996;3:287-289.
14. Steinberg SH, Strickland GT, Pena C, Israel E. Lyme disease surveillance in Maryland, 1992. Ann Epidemiol. 1996;6:24-29.
15. Maryland Dept of Health and Mental Hygiene, Epidemiology and Disease Control Program. Selected communicable diseases in Maryland in 1995. Md Med J. 1996;45:715-718.
16. Dean AG, Dean JA, Coulombier D, et al. Epi Info, Version 6: A Word Processing, Database, and Statistics Program for Public Health on IBM-Compatible Microcomputers. Atlanta, Ga: Centers for Disease Control and Prevention; 1994.
17. Falco RC, Fish D. Ticks parasitizing humans in a Lyme disease endemic area of southern New York State. Am J Epidemiol. 1988;128:1146-1152.
18. Dressier F, Yoshinari NH, Steere AC. The T-cell proliferative assay in the diagnosis of Lyme disease. Ann Intern Med. 1991;115:533-539.
19. Dattwyler RJ, Volkman DJ, Luft BJ, Halperin JJ, Thomas J, Golightly MG. Seronegative Lyme disease: dissociation of spècific T- and B-lymphocyte responses to Borrelia burgdorferi. N Engl J Med. 1988;319:1441-1446.
20. Feder HM Jr, Gerber MA, Luger SW, Ryan RW. Persistence of serum antibodies to Borrelia burgdorferi in patients treated for Lyme disease. Clin Infect Dis. 1992;15:788-793.
21. Aguero-Rosenfeld ME, Nowakowki J, Bittker S, Cooper D, Nadelman RB, Wormser GP. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J Clin Microbiol. 1996;34:1-9.
22. Steere AC, Hutchinson GJ, Rahn DW, et al. Treatment of the early manifestations of Lyme disease. Ann Intern Med. 1983;99:22-26.
23. Dattwyler RJ, Volkman DJ, Conaty SM, Platkin SP, Luft BJ. Amoxycillin plus probenecid versus doxycycline for erythema migrans borreliosis. Lancet. 1990;336:1404-1406.
24. Gerber MA, Shapiro ED, Burke GS, Parcells VJ, Bell GL. Lyme disease in children in southeastern Connecticut: Pediatric Lyme Disease Study Group. N Engl J Med. 1996;335:1270-1274.
25. Nadelman RD, Nowakowski J, Wormser GP. Can Lyme borreliosis be prevented after tick bite? Lancet. 1993;342:1052.
26. Antibiotic prophylaxis of Lyme disease following recognized bite: Bacterial Zoonoses Branch, Division of Vector-Borne Diseases National Center for Infectious Diseases, Centers for Disease Control. Conn Med. 1991;55:691-693.
27. Wormser GP. Lyme disease: insights into the use of antimicrobials for prevention and treatment in the context of experience with other spirochetal infections Mt Sinai J Med. 1995;62:188-195.
28. Magid D, Schwartz B, Craft J, Schwartz JS. Prevention of Lyme disease after tick bites: a cost-effectiveness analysis. N Engl J Med. 1992;327:534-541.
29. Sood SK, Salzman MB, Johnson BJ, et al. Duration of tick attachment as a predictor of the risk of Lyme disease in an area in which Lyme disease is endemic. J Infect Dis. 1997;175:996-999.
30. Steere AC, Taylor E, Wilson ML, Levine JF, Spielman A. Longitudinal assessment of the clinical and epidemiological features of Lyme disease in a defined population. J Infect Dis. 1986;154:295-300.
31. Bingham PM, Galetta SL, Athreya B, Sladky J. Neurologic manifestations in children with Lyme disease. Pediatrics. 1995;96:1053-1056.
32. Nocton JJ, Steere AC. Lyme disease. Adv Intern Med. 1995;40:69-117.
33. Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb Mortal Wkly Rep. 1995;44:590-591.
34. Dressler F, Whalen JA, Reinhardt BN, Steere AC. Western blotting in the serodiagnosis of Lyme disease. J Infect Dis. 1993;167:392-400.
35. Johnson BJB, Robbins KE, Bailey RE, et al. Serodiagnosis of Lyme disease: accuracy of a two-step approach using a flagella-based ELISA and immunoblotting. J Infect Dis. 1996;174:346-353.
36. Ettestad PJ, Campbell GL, Welbel SF, et al. Biliary complications in the treatment of unsubstantiated Lyme disease. J Infect Dis. 1995;171:356-361.