Lysophosphatidylcholine potentiates vascular contractile responses by enhancing vasoconstrictor-induced increase in cytosolic free Ca2+ in rat aorta

European Journal of Pharmacology

Volumn 361, Issue 2-3, 1998, Pages 217-226

  Suenaga, Hiroshi ^a   Kamata, Katsuo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Adrenoceptor agonist; Aorta, rat; Ca2+ channel, voltage dependent; Ca2+ level, cytosolic; Lysophosphatidylcholine; Protein kinase C

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; BRIMONIDINE; CALCIUM; LYSOPHOSPHATIDYLCHOLINE; NICARDIPINE; NORADRENALIN; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHLORIDE; PROTEIN KINASE C;

ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENDOTHELIUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY;

ANIMALS; AORTA; CALCIUM; CYTOSOL; ENZYME INHIBITORS; LYSOPHOSPHATIDYLCHOLINES; MALE; NAPHTHALENES; NICARDIPINE; NOREPINEPHRINE; POTASSIUM CHLORIDE; PROTEIN KINASE C; QUINOXALINES; RATS; RATS, WISTAR; TETRADECANOYLPHORBOL ACETATE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0032553620     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00715-8     Document Type: Article

References (35)

1. Baraban J.M., Gould R.J., Peroutka S.J., Snyder S.H. Phorbol ester effects on neurotransmission: Interaction with neurotransmitters and calcium in smooth muscle. Proc. Natl. Acad. Sci. USA. 82:1985;604-607.
2. Beckeringh J.J., Thoolen M.J.M.C., De Jonge A., Wilffert B., Timmermans P.B.M.W.M., Van Zwieten P.A. Differential effects of the calcium entry blocker D600 on contractions of rat and guinea-pig aortas, elicited by various alpha-1 adrenoceptor agonists. J. Pharmacol. Exp. Ther. 229:1984;515-521.
3. 2+ influx, enhanced DNA synthesis and cytotoxicity in cultured vascular smooth muscle cells. Atherosclerosis. 112:1995;69-76.
4. Daugherty A., Zweifel B.S., Sobel B.E., Schonfeld G. Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits. Arteriosclerosis. 8:1988;768-777.
5. Encabo A., Ferrer M., Conde M.V., Porres A., Gomez-Gerique J.A., Marin J., Balfagon G. Involvement of protein kinase C in the supersensitivity to 5-HT caused by oxidized low-density lipoproteins. Life Sci. 61:1997;1331-1339.
6. Flavahan N.A. Atherosclerosis of lipoprotein-induced endothelial dysfunction: potential mechanisms underlying reduction in EDRF/nitric oxide activity. Circulation. 85:1992;1927-1938.
7. Flavahan N.A. Lysophosphatidylcholine modifies G protein-dependent signaling in porcine endothelial cells. Am. J. Physiol. 264:1993;H722-H727.
8. Galle J., Bassenge E., Busse R. Oxidized low density lipoproteins potentiate vasoconstrictions to various agonists by direct interaction with vascular smooth muscle. Circ. Res. 66:1990;1287-1293.
9. 45Ca influxes in the rat isolated aorta Br. J. Pharmacol. 77:1982;597-604.
10. Godfraind T., Miller R.C., Wibo M. Calcium antagonism and calcium entry blockade. Pharmacol. Rev. 38:1986;321-416.
11. Goldstein J.L., Brown M.S. The low density lipoprotein pathway and its relation to atherosclerosis. Annu. Rev. Biochem. 46:1977;897-930.
12. Henriksen T., Mahoney E.M., Steinberg D. Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: Recognition by receptor for acetylated low density lipoproteins. Proc. Natl. Acad. Sci. USA. 78:1981;6499-6503.
13. 2-adrenoceptor mediated vasoconstrictor responses in perfused tail arteries of spontaneously hypertensive rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 328:1985;388-395.
14. Hoff H.F., Morton R.E. Lipoproteins containing apoB extracted from human aortas. Ann. New York Acad. Sci. 454:1985;183-194.
15. Hollander W., Colombo M., Paddock J. Lipoproteins in human atherosclerotic vessels. Exp. Mol. Pathol. 30:1979;172-189.
16. 2+ sensitivity in α-toxin-permeabilized small mesenteric artery from the rat. Br. J. Pharmacol. 117:1996;1238-1244.
17. Karaki H., Ozaki H., Hori M., Mitsui-Saito M., Amano K., Harada K., Miyamoto S., Nakazawa H., Won K.J., Sato K. Calcium movements, distribution, and functions in smooth muscle. Pharmacol. Rev. 49:1997;157-230.
18. Kugiyama K., Kerns S.A., Morrisett J.D., Roberts R., Henry P.D. Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature. 344:1990;160-162.
19. Kugiyama K., Ohgushi M., Sugiyama S., Murohara T., Fukunaga K., Miyamoto E., Yasue H. lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation. Circ. Res. 71:1992;1422-1428.
20. Locher R., Weisser B., Mengden T., Brunner C., Vetter W. Lysolecithin action on vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 183:1992;156-162.
21. Medgett I.C., Rajanayagam M.A.S. Effects of reduced calcium ion concentration and of diltiazem on vasoconstrictor responses to noradrenaline and sympathetic nerve stimulation in rat isolated tail artery. Br. J. Pharmacol. 83:1984;889-898.
22. 1-adrenoceptor subtypes, inositol phosphates and sources of cell calcium. Pharmacol. Rev. 40:1988;87-119.
23. Murohara T., Kugiyama K., Ohgushi M., Sugiyama S., Ohta Y., Yasue H. LPC in oxidized LDL elicits vasocontraction and inhibits endothelium-dependent relaxation. Am. J. Physiol. 267:1994;H2441-H2449.
24. Rajavashisth T.A., Andalibi A., Territo M.C., Berliner J.A., Navab M., Fogelman M.A., Lusis A.J. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature. 344:1990;254-257.
25. Rasmussen H., Forder J., Kojima I., Scriabine A. TPA-induced contraction of isolated rabbit vascular smooth muscle. Biochem. Biophys. Res. Commun. 122:1984;776-784.
26. Sato K., Ozaki H., Karaki H. Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator fura-2. J. Pharmacol. Exp. Ther. 246:1988;294-300.
27. Schfmann H.J., Lues I. Postjunctional α-adrenoceptors in the isolated saphenous vein of the rabbit: characterization and influence of angiotensin. Naunyn-Schmiedeberg's Arch. Pharmacol. 323:1983;328-334.
28. Steinberg D. Lipoproteins and atherosclerosis: A look back and a look ahead. Arteriosclerosis. 3:1983;283-301.
29. 2+ influx in vascular smooth muscle cells. Am. J. Physiol. 264:1993;C885-C893.
30. 2+ channel antagonist and activator actions in rat tail arteries from normotensive and hypertensive animals. Can. J. Physiol. Pharmacol. 64:1986;909-921.
31. Suenaga H., Kamata K., Kasuya Y. Phorbol ester (PMA)-induced biphasic contraction of the rat aorta and effects of sodium nitroprusside and forskolin on the contraction. Res. Commun. Chem. Pathol. Pharm. 79:1993;313-324.
32. Sugiyama S., Kugiyama K., Ohgushi M., Fujimoto K., Yasue H. Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries: Role of protein kinase C. Circ. Res. 74:1994;565-575.
33. Sybertz E.J., Desiderio D.M., Tetzloff G., Chiu P.J.S. Phorbol dibutyrate contractions in rabbit aorta: Calcium dependence and sensitivity to nitrovasodilators and 8-Br-cyclic GMP. J. Pharmacol. Exp. Ther. 239:1986;78-83.
34. 2+ on the modulation of α-adrenergic-induced contractions in rat aorta, 22, 365-369.
35. Witztum J.L., Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J. Clin. Invest. 88:1991;1785-1792.