Quantification of pyrazinamide and its metabolites in plasma by ionic-pair high-performance liquid chromatography. Implications for the separation mechanism

Journal of Chromatography B: Biomedical Applications

Volumn 706, Issue 2, 1998, Pages 319-328

  Kraemer, Hans Joachim ^a   Feltkamp, Ulrich ^a   Breithaupt, Henning ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

5 Hydroxypyrazinamide; 5 Hydroxypyrazinoic acid; Pyrazinamide; Pyrazinoic acid

Indexed keywords

5 HYDROXYPYRAZINAMIDE; 5 HYDROXYPYRAZINOIC ACID; ALLOPURINOL; DRUG METABOLITE; ISONIAZID; OXIPURINOL; PURINE DERIVATIVE; PYRAZINAMIDE; PYRAZINOIC ACID; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; URIC ACID DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; ION PAIR CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SOLID PHASE EXTRACTION; TECHNIQUE; TUBERCULOSIS;

ADMINISTRATION, ORAL; ANTITUBERCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCADIAN RHYTHM; DRUG STABILITY; HUMANS; PYRAZINAMIDE; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 0032549614     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(97)00519-7     Document Type: Article

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