Macrocyclic bisindolylmaleimides: Synthesis by inter- and intramolecular alkylation

Journal of Organic Chemistry

Volumn 63, Issue 6, 1998, Pages 1961-1973

  Faul, Margaret M ^a   Winneroski, Leonard L ^a   Krumrich, Christine A ^a   Sullivan, Kevin A ^a   Gillig, James R ^b   Neel, David A ^b   Rito, Christopher J ^b   Jirousek, Michael R ^b  

^a ELI LILLY AND COMPANY   (United States)

^b Neuroscience Discovery Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISINDOLYLMALEIMIDE; PROTEIN KINASE C INHIBITOR;

ALKYLATION; ARTICLE; CRYSTALLIZATION; DIABETES MELLITUS; DIABETIC RETINOPATHY; DRUG SYNTHESIS; STEREOCHEMISTRY;

EID: 0032549529     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971980h     Document Type: Article

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50. -1, indicating that no cyclic imide was present.
51. R = 8.0 min.
52. R = 19.9 min.
53. R = 22.7 min.