Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines

Chemico-Biological Interactions

Volumn 109, Issue 1-3, 1998, Pages 237-248

  Ozawa, Shogo ^a,e   Tang, Yong Ming ^a   Yamazoe, Yasushi ^b   Kato, Ryuichi ^c   Lang, Nicholas P ^d   Kadlubar, Fred F ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^e NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Aromatic amine carcinogens; Human; Liver; Pharmacogenetics; Phenol sulfotransferase; Reverse transcriptase polymerase chain reaction

Indexed keywords

4 NITROPHENOL; ARGININE; AROMATIC AMINE; ARYL SULFOTRANSFERASE; CARCINOGEN; COMPLEMENTARY DNA; DOPAMINE; HETEROCYCLIC AMINE; HISTIDINE; LIVER ENZYME; MESSENGER RNA; METHIONINE; SULFOTRANSFERASE; VALINE;

ADULT; AGED; BIOTRANSFORMATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENETIC POLYMORPHISM; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN TISSUE; MALE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SULFATION; THERMOSTABILITY;

AMINES; ARYLSULFOTRANSFERASE; BIOTRANSFORMATION; CARCINOGENS; GENOTYPE; HETEROCYCLIC COMPOUNDS; HUMANS; ISOENZYMES; LIVER; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0032548972     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(97)00135-X     Document Type: Conference Paper

References (32)

1. Jakoby W.B., Ziegler D.M. The enzymes of detoxication. J. Biol. Chem. 265:1990;20715-20718.
2. Kadlubar F.F., Miller E.C., Miller J.A. Hepatic metabolism of N-hydroxy-N-methyl-4-aminoazobenzene and other N-hydroxy arylamines to reactive sulfuric acid esters. Cancer Res. 36:1976;2350-2359.
3. Kato R., Yamazoe Y. Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates. Jpn. J. Cancer Res. 78:1987;297-311.
4. Abu-Zeid M., Yamazoe Y., Kato R. Sulfotransferase-mediated DNA binding of N-hydroxyarylamines(amides) in liver cytosols from human and experimental animals. Carcinogenesis. 13:1992;1307-1314.
5. Gilissen R.A.H.J., Bamforth K.J., Stavenuiter J.F.C., Coughtrie M.W.H., Meerman J.H.N. Sulfation of aromatic hydroxamic acids and hydroxylamines by multiple forms of human liver sulfotransferases. Carcinogenesis. 15:1994;39-45.
6. Chou H.-C., Lang N.P., Kadlubar F.F. Metabolic activation of the N-hydroxy derivatives of the carcinogen 4-aminobiphenyl by human tissue sulfotransferase. Carcinogenesis. 16:1995;413-417.
7. Falany C.N. Molecular enzymology of human liver cytosolic sulfotransferases. Trends Pharmacol. Sci. 12:1991;255-259.
8. Forbes-Bamforth K.J., Coughtrie M.W.H. Identification of a new adult human liver sulfotransferase with specificity for endogenous and xenobiotic estrogens. Biochem. Biophys. Res. Commun. 198:1994;707-711.
9. Wilborn T.W., Comer K.A., Dooley T.P., Reardon I.M., Heinrikson R.T., Falany C.N. Sequence analysis and expression of the cDNA for the phenol-sulfating form of human liver phenol sulfotransferase. Mol. Pharmacol. 43:1993;70-77.
10. Zhu X., Veronese M.E., Sansom L.N., McManus M.E. Molecular characterization of a human aryl sulfotransferase cDNA. Biochem. Biophys. Res. Commun. 192:1993;671-676.
11. Yamazoe Y., Nagata K., Ozawa S., Kato R. Structural similarity and diversity of sulfotransferases. Chem.-Biol. Interact. 92:1994;107-117.
12. Ozawa S., Nagata K., Shimada M. et al. Primary structures and properties of two related forms of aryl sulfotransferases in human liver. Pharmacogenetics. 5:1995;S135-S140.
13. Zhu X., Veronese M.E., Iocco P., McManus M.E. cDNA cloning and expression of a new form of human aryl sulfotransferase. Int. J. Biochem. Cell Biol. 28:1996;565-571.
14. Wood T.C., Aksoy I.A., Aksoy S., Weinshilboum R.M. Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization. Biochem. Biophys. Res. Commun. 198:1994;1119-1127.
15. Her C., Raftogianis R., Weinshilboum R.M. Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization and chromosomal localization. Genomics. 33:1996;409-420.
16. Bernier F., Soucy P., Luu-The V. Human phenol sulfotransferase gene contains two alternative promoters: structure and expression of the gene. DNA Cell Biol. 15:1996;367-375.
17. Aksoy I.A., Weinshilboum R.M. Human thermolabile phenol sulfotransferase gene (STM): molecular cloning and structural characterization. Biochem. Biophys. Res. Commun. 208:1995;786-795.
18. Dooley T.P., Huang Z. Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16. Biochem. Biophys. Res. Commun. 228:1996;134-140.
19. Chou H.-C., Lang N.P., Kadlubar F.F. Metabolic activation of the N-hydroxy arylamines and N-hydroxy heterocyclic amines by human sulfotransferase(s). Cancer Res. 55:1995;525-529.
20. Ozawa S., Chou H.-C., Kadlubar F.F., Nagata K., Yamazoe Y., Kato R. Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo- [4,5-b]pyridine by cDNA-expressed human and rat arylsulfotransferases. Jpn. J. Cancer Res. 85:1994;1220-1228.
21. Pacifici G.M., Temellini A., Castiglioni M., D'Alessandro C., Ducci A., Giuliani L. Interindividual variability of the human hepatic sulphotransferases. Chem.-Biol. Interact. 92:1994;219-231.
22. Weinshilboum R., Aksoy I. Sulfation pharmacogenetics in humans. Chem.-Biol. Interact. 92:1994;233-246.
23. Coughtrie M.W.H. Sulphation catalysed by the human cytosolic sulphotransferases-chemical defence or molecular terrorism? Hum. Exp. Toxicol. 15:1996;547-555.
24. Rappolee D.A., Mark D., Banda M.J., Werb Z. Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping. Science. 241:1988;708-712.
25. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
26. Foldes A., Meek J.L. Rat brain phenolsulfotransferase-partial purification and some properties. Biochim. Biophys. Acta. 327:1973;365-374.
27. Campbell N.R.C., Van Loon J.A., Weinshilboum R.M. Human liver phenol sulfotransferase: assay conditions, biochemical properties and partial purification of isozymes of the thermostable form. Biochem. Pharmacol. 36:1987;1435-1446.
28. Veronese M.E., Burgess W., Zhu X., McManus M.E. Functional characterization of two human sulphotransferase cDNAs that encode monoamine- and phenol-sulphating forms of phenol sulphotransferase: substrate kinetics, thermal-stability and inhibitor-sensitivity studies. Biochem. J. 302:1994;497-502.
29. Gilliland G., Perrin S., Blanchard K., Bunn H.F. Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction. Proc. Natl. Acad. Sci. USA. 87:1990;2725-2729.
30. Shapiro S.S., Wilk M.B. An analysis of variance test for normality (complete samples). Biometrika. 52:1965;591-611.
31. Falany C.N., Krasnykh V., Falany J.L. Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase. J. Steroid Biochem. Mol. Biol. 52:1995;529-539.
32. Van Loon J., Weinshilboum R. Human platelet phenol sulfotransferase: familial variation in thermal stability of the TS form. Biochem. Genet. 22:1984;997-1014.