Efficient transduction of hemopoietic CD34+ progenitors of human origin using an original retroviral vector derived from Fr-MuLV-FB29: In vitro assessment

Human Gene Therapy

Volumn 9, Issue 2, 1998, Pages 207-216

  Cohen Haguenauer, Odile ^a   Restrepo, Luz Marina ^a   Masset, Michel ^a   Bayer, Jan ^a   Dal Cortivo, Liliane ^a   Marolleau, Jean Pierre ^a   Benbunan, Marc ^a   Boiron, Michel ^a   Marty, Michel ^a  

^a SAINT LOUIS HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; VIRUS VECTOR;

ARTICLE; BONE MARROW; COLONY FORMING UNIT GM; FRIEND LEUKEMIA VIRUS; GENETIC ENGINEERING; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; RETROVIRUS; UMBILICAL CORD BLOOD; VIRUS INFECTIVITY;

FRIEND MURINE LEUKEMIA VIRUS; MURINAE; MURINE LEUKEMIA VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0032548403     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.2-207     Document Type: Article

References (4)

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2. + enriched cord blood and Gaucher bone marrow cells by retroviral vector carrying the glucocerebrosidase gene. Gene Ther. 1, 176-184.
3. BIENZLE, D., ABRAMS-OGG, A.C., KRUTH, S.A., ACKLANDSNOW, J., CARTER, R.F., DICK, J., JACOBS, R.M., KAMELREID, S., and DUBE, I.D. (1994). Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation. Proc. Natl. Acad. Sci. USA 91, 350-354.
4. BLAESE, R.M., CULVER, K.W., MILLER, D.A., CARTER, C.S., FLEISHER, T., CLERICI, M., SHEARER, G., CHANG, L., CHIANG, Y., TOLTOSHEV, P., GREENBLATT, J.J., ROSENBERG, S.A., KLEIN, H., BERGER, M., MULLEN, C.A., RAMSEY, W.J., MORGAN, R.A., and ANDERSON, F.W. (1995). T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after 4 years. Science 270, 475-480.