Synthesis and cytotoxicity of 2-methyl-4,9-dihydro-1-substituted-1H- imidazo[4,5-g]quinoxaline-4,9-diones and 2,3-disubstituted-5,10-pyrazino[2,3- g]quinoxalinediones

Journal of Medicinal Chemistry

Volumn 41, Issue 24, 1998, Pages 4716-4722

  Yoo, Hee Won ^a,b   Suh, Myung Eun ^a   Park, Sang Woo ^b,c  

^a Ewha Womans University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Sang Woo Park ^*

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 4,9 DIHYDRO 1 (4 BROMOPHENYL) 1H IMIDAZOL[4,5 G]QUINOXALINE 4,9 DIONE; 2 METHYL 4,9 DIHYDRO 1H IMIDAZO[4,5 G]QUINOXALINE 4,9 DIONE DERIVATIVE; 2,3 DIETHYL 5,10 PYRAZINO[2,3 G]QUINOXALINEDIONE; 5,10 PYRAZINO[2,3 G]QUINOXALINEDIONE DERIVATIVE; 5,7 DICHLORO 5,8 QUINOXALINEDIONE; ANTINEOPLASTIC AGENT; CISPLATIN; DNA; DOXORUBICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON ADENOCARCINOMA; COMPUTER GRAPHICS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; INTERCALATION COMPLEX; LUNG ADENOCARCINOMA; MOLECULAR MODEL; STOMACH ADENOCARCINOMA;

ANTINEOPLASTIC AGENTS; DINUCLEOSIDE PHOSPHATES; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IMIDAZOLES; INTERCALATING AGENTS; MODELS, MOLECULAR; QUINOXALINES; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0032548012     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970695n     Document Type: Article

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