Enzymatic resolution of (±)-threo-methylphenidate

Tetrahedron Asymmetry

Volumn 9, Issue 12, 1998, Pages 2133-2136

  Prashad, Mahavir ^a   Har, Denis ^a   Repic, Oljan ^a   Blacklock, Thomas J ^a   Giannousis, Peter ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN A; METHYLPHENIDATE; SUBTILISIN;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0032547127     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00220-1     Document Type: Article

References (7)

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2. Maxwell, R. A.; Chaplin, E.; Eckhardt, S. B.; Soares, J. R.; Hite, G. J. Pharmacol. Exp. Ther. 1970, 173, 158-165.
3. Patrick, K. S.; Caldwell, R. W.; Ferris, R. M.; Breese, G. R. J. Pharmacol. Exp. Ther. 1987, 241, 152-158.
4. Harris, M. C. J.; Zavareh, H. S. World Patent application WO 97/27176, July 31, 1997.
5. Zavareh, H. S. World Patent application WO 97/32851, September 12, 1997.
6. Soloshonok, V. A. Biocatalytic entry to enantiomerically pure β-amino acids in Enantioselective Synthesis of β-Amino Acids, Juaristi, E.; Eds. Wiley-VCH: New York, 1997, 443-464.
7. Chenevert, R.; Rhlid, R. B.; Letourneau, M.; Gagnon, R.; D'Astous, L. Tetrahedron: Asymmetry 1993, 4, 1137-1140.