Changes in intracellular Ca2+ concentrations related to PDT-induced apoptosis in photosensitized human cancer cells

Cancer Letters

Volumn 128, Issue 2, 1998, Pages 205-210

  Tajiri, Hisao ^a   Hayakawa, Akemi ^b   Matsumoto, Yoshinari ^b   Yokoyama, Itsuo ^b   Yoshida, Shigeaki ^a  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; DNA fragmentation; Intracellular Ca2+ concentration; Photodynamic therapy; Photofrin

Indexed keywords

CALCIUM ION; DNA FRAGMENT; PHOTOFRIN; ANTINEOPLASTIC AGENT; CALCIUM; DNA; PHOTOFRIN II; PHOTOSENSITIZING AGENT;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXCIMER LASER; HUMAN; HUMAN CELL; LASER MICROSCOPY; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; CELL CULTURE; DNA DAMAGE; DRUG EFFECT; METABOLISM; PATHOLOGY; PHOTOCHEMOTHERAPY; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CALCIUM; CARCINOMA, SQUAMOUS CELL; DIHEMATOPORPHYRIN ETHER; DNA DAMAGE; DNA, NEOPLASM; HUMANS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; TUMOR CELLS, CULTURED;

EID: 0032546653     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00066-4     Document Type: Article

References (21)

1. Agarwal M.L., Clay M.E., Harvay E.J. Photodynamic therapy induces rapid cell death by apoptosis in L5178 mouse lymphoma cells. Cancer Res. 51:1991;5993-5996.
2. He X.Y., Sikes R.A., Thomsen S., Chung L.W.K., Jacques S.L. Photodynamic therapy-induced programmed cell death in carcinoma cell line. SPIE Proc. 1881:1993;285-295.
3. Oleinick N.L., Agarwal M.L., Berger N.A. Signal transduction and metabolic changes during tumor cell apoptosis following phthalocyanine-sensitized photodynamic therapy. SPIE Proc. 1881:1993;252-261.
4. Laukka M.A., Wang K.K., Bonner J.A. Apoptosis occurs in lymphoma cells but not in hepatoma cells following ionizing radiation and photodynamic therapy. Dig. Dis. Sci. 39:1994;2467-2475.
5. Tajiri H., Shinomiya N., Hayakawa A., Mastsumoto Y., Yoshida S. Photodynamic therapy-induced rapid cell death by apoptosis in human pancreatic carcinoma transplanted into nude mice. J. Clin. Biochem. Nutr. 21:1996;29-37.
6. Canman C.E., Tang H., Normolle D.P., Lawrence T.S., Maybaum J. Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine: implications for mechanisms of resistance and cytotoxicity. Proc. Natl. Acad. Sci. USA. 89:1992;10474-10478.
7. Gomer C.J., Rucker N., Ferrario A., Wong S. Properties and applications of photodynamic therapy. Radiat. Res. 120:1989;1-18.
8. Henderson B.W., Dougherty T.J. How does photodynamic therapy work? Photochem. Photobiol. 55:1992;145-157.
9. Weishaupt K., Gomer C.J., Dougherty T.J. Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumor. Cancer Res. 36:1976;2326-2329.
10. Specht L.G., Rodgers M.A.J. Plasma membrane depolarization and calcium influx during cell injury by photodynamic action. Biochim. Biophys. Acta. 1070:1991;60-68.
11. Ben-Hur E., Freud A., Canfi A., Livne A. The role of glycolysis and univalent ions in phthalocyanine-sensitized photohaemolysis of human erythrocytes. Int. J. Radiat. Biol. 59:1991;797-806.
12. Ben-Hur E., Dubelman T.M.A.R., Van Stevenick J. Effect of fluoride on inhibition of plasma membrane functions in Chinese hamster ovary cells photosensitized by aluminum phthalocyanine. Radiat. Res. 131:1992;47-52.
13. Agarwal M.L., Larkin H.E., Zaidi S.I.A., Mukhtar H., Oleinick N.L. Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma. Cancer Res. 53:1993;5897-5902.
14. Dennis E.A., Rhee S.G., Billah M.M., Hannum Y.A. Role of phospholipases in generating lipid second messengers in signal transduction. FASEB J. 5:1991;2068-2077.
15. Berridge M.J., Irvine R.F. Inositol trisphosphate,a novel second messenger in cellular signal transduction. Nature. 312:1984;315-321.
16. Berridge M.J. Inositol triphosphate and diacylglycerol: two interacting second messengers. Ann. Rev. Biochem. 56:1987;159-193.
17. Exton J.H. Role of phosphoinositides in the regulation of liver function. Hepatology. 8:1988;152-166.
18. Cohen P. The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58:1989;453-508.
19. Rao A. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today. 15:1994;274-281.
20. Yokoyama I., Hayashi S., Sato E., Kobayashi T., Negita M., Uchida K., Takagi H. Enhancement of tumor proliferation by cyclosporine A in early phase of experimental hepatic metastasis. Jpn. J Cancer Res. 85:1994;704-709.
21. Fruman D.A., Mather P.A., Burakoff S.J., Bierer B.E. Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. Eur. J. Immunol. 22:1992;2513-2517.