Evaluation of a GPIIb/IIIa antagonist YM337 in a primate model of middle cerebral artery thrombosis

European Journal of Pharmacology

Volumn 345, Issue 2, 1998, Pages 185-192

  Kaku, Seiji ^a   Umemura, Kazuo ^a   Mizuno, Atsuhiro ^a   Yano, Shinya ^b   Suzuki, Ken Ichi ^b   Kawasaki, Tomihisa ^b   Nakashima, Mitsuyoshi ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Inst for Drug Discovery Research   (Japan)

Author keywords

Antibody; Cerebral; Humanized; Monkey; Platelet GPIIb IIIa; Thrombosis

Indexed keywords

ADENOSINE DIPHOSPHATE; FIBRINOGEN; FIBRINOGEN RECEPTOR ANTAGONIST; IMMUNOGLOBULIN F(AB) FRAGMENT; OZAGREL; ROSE BENGAL; THROMBOXANE B2; THROMBOXANE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; YM 337;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE CEREBRAL ARTERY OCCLUSION; MONKEY; NEUROLOGIC DISEASE; NONHUMAN; PHOTOCHEMOTHERAPY; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE COUNT; THROMBOSIS;

ANIMALS; ENZYME INHIBITORS; IMMUNOGLOBULIN FAB FRAGMENTS; INTRACRANIAL EMBOLISM AND THROMBOSIS; METHACRYLATES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SAIMIRI; THROMBOXANE-A SYNTHASE;

EID: 0032546271     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00005-3     Document Type: Article

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