A convenient and mild procedure for the reduction of amino acids using amberlyst 15 - NaBH4 - LiCl

Tetrahedron Letters

Volumn 39, Issue 8, 1998, Pages 917-918

  Anand, Ramesh C ^a   Vimal, ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMBERLYST 15; AMINO ACID; AMINOALCOHOL; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG INDUSTRY; NONHUMAN; PEPTIDE SYNTHESIS; REDUCTION;

EID: 0032546069     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10691-8     Document Type: Article

References (13)

1. 1. (a) Bolm, C. Angew. Chem., Int. Ed. Engl. 1991, 30, 542.
2. (b) Rossiter, B.E; Swingle N.M. Chem. Rev. 1992, 92, 771 and references cited therein.
3. 2. McKennon, M.J.; Meyers, A.I.; Drauz, K.; Schwarm, M. J. Org. Chem. 1993, 58, 3568 and references cited therein.
4. 3. Wu, S. ; Takeya, R.; Eto, M.; Tomizawa, C. J.Pestic.Sci. 1987, 12, 221
5. 4. (a) Anand, R.C.; Singh, V. Tetrahedron 1993, 49, 6515.
6. (b) Anand, R.C.; Selvapalam, N. J. Chem, Res. (S) and (M) (in press).
7. 5. Abiko, A.; Masamune, S. Tetrahedron Lett. 1992, 33, 5517 and references cited therein.
8. 6. Anand R.C.; Vimal Synth. Commun. (Submitted).
9. 2.
10. 8. For specific rotation comparison, it was transformed into hydroiodide.
11. 9. After completion of reaction, it was worked up by treatment with triethylamine, removal of excess of amine and THF and then isolating the product by chromatography on silical gel.
12. 10. Financial support from CSIR, New Delhi through project no. 1(1343)95-EMR-II is gratefully acknowledged.
13. 11. Sudharshan, M.; Hultin, P.G. Synlelt. 1997, 171.