Neurochemical characterization and distribution of enteric GABAergic neurons and nerve fibres in the human colon

Journal of the Autonomic Nervous System

Volumn 68, Issue 1-2, 1998, Pages 33-42

  Krantis, Anthony ^a   Nichols, Kim ^a   Staines, William ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Enkephalin; GABA transaminase (GABA T) human colon; GABAergic; Immunohistochemistry; NADPH diaphorase; Nitric oxide (NO); NO synthase; Somatostatin

Indexed keywords

4 AMINOBUTANEPHOSPHONIC ACID; ENKEPHALIN; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ARTICLE; CELLULAR DISTRIBUTION; HUMAN; HUMAN TISSUE; INTESTINE INNERVATION; INTESTINE MOTILITY; NERVE CELL NETWORK; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; PERISTALSIS; PRIORITY JOURNAL;

EID: 0032545622     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(97)00113-6     Document Type: Article

References (54)

1. Alho H., Ferrarese C., Vicini S., Vaccarino F. Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides. Brain Res. 467(2):1988;193-204.
2. Aoki C., Pickel V.M. Neuropeptide Y in cortex and striatum. Ultrastructural distribution and coexistence with classical neurotransmitters and neuropeptides. Ann. N. Y. Acad. Sci. 611:1990;186-205. review.
3. Calignano A., Whittle B.J.R., Di Rosa M., Moncada S. Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo. Eur. J. Pharmacol. 229:1992;273-276.
4. Cherubini E., North R.A. γ-Aminobutyric acid actions on neurons of guinea-pig myenteric plexus. Br. J. Pharmacol. 82:1984;93-100.
5. Cherubini E., North R.A. Inhibition of calcium spikes and transmitter release by γ-aminobutyric acid in the guinea-pig myenteric plexus. Br. J. Pharmacol. 82:1984;101-106.
6. M. Costa, S.J.H. Brookes, S. Waterman, R. Mayo, Enteric neuronal circuitry and transmitters controlling intestinal motor function, in: G.E. Holle, J.D. Wood (Eds.), Advances in the Innervation of the Gastrointestinal Tract, Elsevier Science Publishers, Amsterdam, 1992, pp. 115-121.
7. Costa M., Furness J.B., Gibbins I.L. Chemical coding of enteric neurons. Prog. Brain Res. 68:1986;217-239.
8. Costa M., Furness J.B., Llewellyn-Smith J., Davies B., Oliver J. An immunohistochemical study of the projections of somatostatin-containing neurons in the guinea-pig intestine. Neuroscience. 5:1980;841-852.
9. E.E. Daniel, S.M. Collins, J.-A. Fox, J. Huizinga, Pharmacology of drugs acting on gastrointestinal motility, in: Handbook of Physiology, sec. 6, vol. 1, The Gastrointestinal System, 1989, pp. 715-758.
10. Davanger S., Hjelle O.P., Babaie E., Larsson L.-I., Hougaard D., Storm-Mathisen J., Ottersen O.P. Colocalization of γ-aminobutyrate and gastrin in the rat antrum: An immunocytochemical and in situ hybridization study. Gastroenterology. 107:1994;137-148.
11. Erdo S.L. Peripheral GABAergic mechanisms. Trends Neurosci. 7:1985;205-208.
12. S.L. Erdo, N.G. Bowery, GABAergic Mechanisms in Mammalian Periphery, Raven, New York, 1986.
13. Ferri G.-L., Adrian T.E., Ghatei M.A., O'Shaughnessy D.J., Probert L., Lee Y.C., Buchan A.M.J., Polak J.M., Bloom S.R. Tissue localisation and relative distribution of regulatory peptides in separated layers from the human bowel. Gastroenterology. 84:1983;777-786.
14. Gilon P., Mallefet J., De Vriendt C., Pauwels S., Geffard M., Campistron G., Remacle C. Immunocytochemical and autoradiographic studies of the endocrine cells interacting with GABA in the rat stomach. Histochemistry. 93:1990;645-654.
15. Gilon P., Reusens-Billen B., Remacle C., Janssens de Varebeke Ph., Pauwels G., Hoett J.J. Localization of high-affinity GABA uptake and GABA content in the rat duodenum during development. Cell Tissue Res. 249:1987;593-600.
16. Grider J.R. Interplay of somatostatin, opioid and GABA neurons in the regulation of the peristaltic reflex. Am. J. Physiol. (Gastrointest. Liver Physiol.). 267(30):1994;G696-G701.
17. Grider J.R. Identification of neurotransmitters regulating intestinal peristaltic reflex in humans. Gastroenterology. 97:1989;1414-1419.
18. Grider J.R. Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis. Am. J. Physiol. (Gastrointest. Liver Physiol.). 264(27):1993;G334-G340.
19. Grider J.R., Arimura A., Makhlouf G.M. Role of somatostatin neurons in intestinal peristalsis: Facilitatory interneurons in descending pathways. Am. J. Physiol. (Gastrointest. Liver Physiol.). 253(16):1987;G434-G438.
20. Grider J.R., Makhlouf G.M. Regulation of the peristaltic reflex by peptides of the myenteric plexus. Arch. Int. Pharmacodyn. Ther. 303:1990;232-251.
21. Guillemin R. Somatostatin inhibits the release of acetylcholine induced electrically in the myenteric plexus. Endocrinology. 99:1976;1653-1654.
22. Guo Y.-S., Thompson J.C., Singh P. Effect of γ-aminobutyric acid on bombesin-evoked release of somatostatin and gastrin from isolated rat stomach. Regul. Pept. 24:1989;179-186.
23. Gustafsson B.I., Delbro D.S. Tonic inhibition of small intestinal motility by nitric oxide. J. Auton. Nerv. Syst. 44:1993;179-187.
24. Gustafsson B.I., Delbro D.S. Neurogenic inhibition of duodenal and jejunal motility in the anaesthetized rat. Eur. J. Pharmacol. 257:1994;227-233.
25. Hardcastle J., Hardcastle P.T., Mathias W.J. The influence of the γ-amino butyric acid (GABA) antagonist bicuculline on transport processes in rat small intestine. J. Pharm. Pharmacol. 43:1991;128-130.
26. Harty R.F., Boharski M.G., Bochna G.S., Carr T.A., Eagan P.E., Rings M., Lassiter D.C., Pour M.P., Schafter D.F., Markin R.S. γ-Aminobutyric acid localization and function as modulator of cholinergic neurotransmission in rat antral mucosal/submucosal fragments. Gastroenterology. 101:1991;78-1186.
27. Harty R.F., Franklin P.A. GABA affects the release of gastrin and somatostatin from rat antral mucosa. Nature. 303:1983;623-624.
28. Hills J.M., Jessen K.R., Mirsky R. An immunohistochemical study of the distribution of enteric GABA-containing neurons in the rat and guinea-pig intestine. Neuroscience. 22:1987;301-312.
29. 3H -GABA uptake in mucosal epithelial cells of the rat stomach Gut. 29:1988;1549-1556.
30. Katayama Y., North R.A. The action of somatostatin on neurons of the myenteric plexus of the guinea pig ileum. J. Physiol. London. 303:1980;315-323.
31. D.I.B. Kerr, J. Ong, GABAergic mechanisms in the gut: Their role in the regulation of gut motility, in: S.L. Erdo, N.G. Bowery (Eds.), GABAergic Mechanisms in the Mammalian Periphery, Raven Press, New York, 1986, pp. 153-174.
32. Keast J.R., Furness J.B., Costa M. Somatostatin in human enteric nerves: Distribution and characterization. Cell Tissue Res. 237:1984;299-308.
33. 3H ]aminobutyric acid by neural elements and vascular nerves of the rat intestinal submucosa Neurosci. Lett. 109:1990;1-6.
34. 3H ]GABA-labelled nerve fibre networks in the rat intestinal mucosa J. Auton. Nerv. Syst. 34:1991;195-200.
35. Krantis A., Harding R.K. The distribution of GABA-transaminase in the myenteric plexus of rat small and large intestine: A histochemical analysis. Neurosci. Lett. 64:1986;85-90.
36. 3H ]γ-aminobutyrate-accumulating neural elements in guinea-pig intestine: Evidence for a transmitter function of γ-aminobutyrate Neuroscience. 17:1986;1243-1255.
37. 3H ]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon J. Auton. Nerv. Syst. 47:1994;225-232.
38. A receptor immunoreactivity in NO synthase positive myenteric neurons. J. Auton. Nerv. Syst. 53:1995;157-165.
39. MacNaughton W.K., Pineau B.C., Krantis A. γ-Aminobutyric acid stimulates electrolyte transport in the guinea-pig ileum in vitro. Gastroenterology. 110:1996;498-507.
40. Murthy K.S., Grider J.R., Jin J.G., Makhlouf G.M. Interplay of VIP and nitric oxide in the regulation of neuromuscular activity in the gut. Arch. Int. Pharmacodyn Ther. 329(1):1995;27-38.
41. Nagai T., McGeer P.L., McGeer E.G. Distribution of GABA-T-intensive neurons in the rat forebrain and midbrain. J. Comp. Neurol. 218:1983;220-238.
42. Nichols K., Staines W., Krantis A. Neural sites of the human colon colocalize nitric oxide synthase-related NADPH diaphorase activity and neuropeptide Y. Gastroenterology. 107:1994;968-975.
43. Nichols K., Staines W., Wu J.-Y., Krantis A. Immunopositive GABAergic neural sites display nitric oxide synthase-related NADPH diaphorase activity in the human colon. J. Auton. Nerv. Syst. 50:1995;253-262.
44. Spike R.C., Todd A.J., Johnston H.M. Coexistence of NADPH diaphorase with GABA, glycine and acetylcholine in rat spinal cord. J. Comp. Neurol. 335:1993;320-333.
45. Sanders K.M., Ward S.M. Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission. Am. J. Physiol. 262:1992;G379-G392.
46. Saito N., Tanaka C. Immunohistochemical demonstration of GABA-containing neurons in the guinea-pig ileum using purified GABA antiserum. Brain Res. 376:1986;78-84.
47. Staines W.A., Oertel W., Wu J.-Y., Hokfelt T. Immunohistochemistry of amino acid transmitter enzymes. Acta Neurol. Scand. 69:1984;306-312.
48. Tanaka C. γ-Aminobutyric acid in peripheral tissues. Life Sci. 37:1985;2221-2235.
49. Tanaka C., Taniyama K. Substance P provoked gamma-aminobutyric acid release from the myenteric plexus of the guinea-pig small intestine. J. Physiol. London. 362:1985;319-329.
50. Tsai L.H., Rsai W.H., Wu J.-Y. Action of myenteric GABAergic neurons in guinea-pig stomach. Neurochem. Int. 23:1993;187-193.
51. Vincent S.R., Kimura H., McGeer E.G. GABA-transaminase in the basal ganglia: A pharmacohistochemical study. Brain Res. 251:1982;93-104.
52. Wattchow D.A., Furness J.B., Costa M. Distribution and coexistence of peptides in nerve fibres of the external muscle of the human gastrointestinal tract. Gastroenterology. 95:1988;32-41.
53. Wiley J., Owyang C. Somatostatin inhibits cAMP-mediated cholinergic transmission in the myenteric plexus. Am. J. Physiol. (Gastro. Liver Physiol.). 253(16):1987;G607-G612.
54. Williamson S., Pompolo S., Furness J.B. GABA and nitric oxide synthase immunoreactivities are colocalized in a subset of inhibitory motor neurons of the guinea-pig small intestine. Cell Tissue Res. 284:1996;29-37.