메뉴 건너뛰기




Volumn 781, Issue 1-2, 1998, Pages 212-217

Effect of nicardipine, a Ca2+ channel blocker, on pyruvate dehydrogenase activity and energy metabolites during cerebral ischemia and reperfusion in gerbil brain

Author keywords

Ca2+ channel blocker; Cerebral ischemia; Energy metabolites; Nicardipine; PDH activity

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL BLOCKING AGENT; CREATINE PHOSPHATE; LACTIC ACID; NICARDIPINE; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 0032545530     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01246-8     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 0023905674 scopus 로고
    • Comparative protective effects of nicardipine, flunarizine, lidoflazine, and nimodipine against ischemic injury in the hippocampus of the Mongolian gerbil
    • Alps B.J., Calder C., Haas W.K., Wilson A.D. Comparative protective effects of nicardipine, flunarizine, lidoflazine, and nimodipine against ischemic injury in the hippocampus of the Mongolian gerbil. Br. J. Pharmacol. 93:1988;877-883.
    • (1988) Br. J. Pharmacol. , vol.93 , pp. 877-883
    • Alps, B.J.1    Calder, C.2    Haas, W.K.3    Wilson, A.D.4
  • 2
    • 0001105925 scopus 로고
    • Nicardipine and phenytoin prevention of cerebral ischemic cell change in a new rat survival model of brief four vessel occlusion
    • Suppl.
    • Alps B.J., Haas W.K. Nicardipine and phenytoin prevention of cerebral ischemic cell change in a new rat survival model of brief four vessel occlusion. Neurology. 35:1985;141. Suppl.
    • (1985) Neurology , vol.35 , pp. 141
    • Alps, B.J.1    Haas, W.K.2
  • 3
    • 0020629581 scopus 로고
    • The dissociative anaesthetics, ketamine and phenycyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate
    • Anis N.A., Berry S.C., Burton N.R., Lodge D. The dissociative anaesthetics, ketamine and phenycyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br. J. Pharmacol. 79:1983;565-575.
    • (1983) Br. J. Pharmacol. , vol.79 , pp. 565-575
    • Anis, N.A.1    Berry, S.C.2    Burton, N.R.3    Lodge, D.4
  • 4
    • 0024581875 scopus 로고
    • Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats
    • Berger L., Hakim A.M. Nimodipine prevents hyperglycemia-induced cerebral acidosis in middle cerebral artery occluded rats. J. Cereb. Blood Flow Metab. 9:1989;58-64.
    • (1989) J. Cereb. Blood Flow Metab. , vol.9 , pp. 58-64
    • Berger, L.1    Hakim, A.M.2
  • 5
    • 0023595269 scopus 로고
    • Effects of cerebroprotective agents on cerebral blood flow and on post ischemic energy metabolism in the rat brain
    • Bielenberg G.W., Beck T., Sauer D., Burniol M., Krieglstein J. Effects of cerebroprotective agents on cerebral blood flow and on post ischemic energy metabolism in the rat brain. J. Cereb. Blood Flow Metab. 7:1987;480-488.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 480-488
    • Bielenberg, G.W.1    Beck, T.2    Sauer, D.3    Burniol, M.4    Krieglstein, J.5
  • 6
    • 0023555492 scopus 로고
    • Effects of calcium entry blocker emopamil on postischemic energy metabolism of the isolated perfused rat brain
    • Bielenberg G.W., Haubruck H., Krieglstein J. Effects of calcium entry blocker emopamil on postischemic energy metabolism of the isolated perfused rat brain. J. Cereb. Blood Flow Metab. 7:1987;489-496.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 489-496
    • Bielenberg, G.W.1    Haubruck, H.2    Krieglstein, J.3
  • 7
    • 0022154565 scopus 로고
    • The calcium signal
    • Carafoli E., Penniston J.T. The calcium signal. Sci. Am. 253(11):1985;50-58.
    • (1985) Sci. Am. , vol.253 , Issue.11 , pp. 50-58
    • Carafoli, E.1    Penniston, J.T.2
  • 8
    • 0024409241 scopus 로고
    • Pyruvate dehydrogenase activity in the rat cerebral cortex following cerebral ischemia
    • Cardell M., Koide T., Wieloch T. Pyruvate dehydrogenase activity in the rat cerebral cortex following cerebral ischemia. J. Cereb. Blood Flow Metab. 9:1989;350-357.
    • (1989) J. Cereb. Blood Flow Metab. , vol.9 , pp. 350-357
    • Cardell, M.1    Koide, T.2    Wieloch, T.3
  • 10
    • 0020950844 scopus 로고
    • Involvement of mitochondria in ischemic cell injury and in regulation of intracellular calcium
    • Fiscum G. Involvement of mitochondria in ischemic cell injury and in regulation of intracellular calcium. Am. J. Emerg. Med. 1:1983;147-152.
    • (1983) Am. J. Emerg. Med. , vol.1 , pp. 147-152
    • Fiscum, G.1
  • 12
    • 0018966630 scopus 로고
    • Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat: I. Local cerebral blood flow and glucose utilization
    • Ginsberg M.D., Welsh F.A., Budd W.W. Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat: I. Local cerebral blood flow and glucose utilization. Stroke. 11:1980;347-354.
    • (1980) Stroke , vol.11 , pp. 347-354
    • Ginsberg, M.D.1    Welsh, F.A.2    Budd, W.W.3
  • 14
    • 0022920059 scopus 로고
    • Cerebral acidosis in focal ischemia: II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat
    • Hakim A.M. Cerebral acidosis in focal ischemia: II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 6:1986;676-683.
    • (1986) J. Cereb. Blood Flow Metab. , vol.6 , pp. 676-683
    • Hakim, A.M.1
  • 15
    • 0016668681 scopus 로고
    • Experimental cerebral vasospasm in cats: Modification by a new synthetic vasodilator YC-93
    • Handa J., Yoneda S., Koyama T., Matsuda M., Handa H. Experimental cerebral vasospasm in cats: modification by a new synthetic vasodilator YC-93. Surg. Neurol. 3:1975;195-199.
    • (1975) Surg. Neurol. , vol.3 , pp. 195-199
    • Handa, J.1    Yoneda, S.2    Koyama, T.3    Matsuda, M.4    Handa, H.5
  • 16
    • 0019846592 scopus 로고
    • Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex
    • Hansen A.J., Zeuthen T. Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta. Physiol. Scand. 113:1981;437-445.
    • (1981) Acta. Physiol. Scand. , vol.113 , pp. 437-445
    • Hansen, A.J.1    Zeuthen, T.2
  • 17
    • 0021180170 scopus 로고
    • Extracellular pH, potassium and calcium activities in progressive ischemia of rat cortex
    • Harris R., Symon L. Extracellular pH, potassium and calcium activities in progressive ischemia of rat cortex. J. Cereb. Blood Flow Metab. 4:1984;178-186.
    • (1984) J. Cereb. Blood Flow Metab. , vol.4 , pp. 178-186
    • Harris, R.1    Symon, L.2
  • 18
    • 0022358421 scopus 로고
    • Effect of nimodipine on cerebral metabolism during ischemia and recirculation in the Mongolian gerbil
    • Heffez D.S., Passonneau J.V. Effect of nimodipine on cerebral metabolism during ischemia and recirculation in the Mongolian gerbil. J. Cereb. Blood Flow Metab. 5:1985;523-528.
    • (1985) J. Cereb. Blood Flow Metab. , vol.5 , pp. 523-528
    • Heffez, D.S.1    Passonneau, J.V.2
  • 19
    • 0019827971 scopus 로고
    • An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates
    • Hinman L.M., Blass J.P. An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates. J. Biol. Chem. 256:1981;6583-6586.
    • (1981) J. Biol. Chem. , vol.256 , pp. 6583-6586
    • Hinman, L.M.1    Blass, J.P.2
  • 20
    • 0017229988 scopus 로고
    • The regulation of pyruvate dehydrogenase in brain in vivo
    • Jope R., Blass J.P. The regulation of pyruvate dehydrogenase in brain in vivo. J. Neurochem. 26:1976;709-714.
    • (1976) J. Neurochem. , vol.26 , pp. 709-714
    • Jope, R.1    Blass, J.P.2
  • 21
    • 0031019321 scopus 로고    scopus 로고
    • Ischemic tolerance phenomenon from an approach of energy metabolism and the mitochondrial enzyme activity of pyruvate dehydrogenase in gerbils
    • Katayama Y., Muramatsu H., Kamiya T., McKee A., Terashi A. Ischemic tolerance phenomenon from an approach of energy metabolism and the mitochondrial enzyme activity of pyruvate dehydrogenase in gerbils. Brain Res. 746:1997;126-132.
    • (1997) Brain Res. , vol.746 , pp. 126-132
    • Katayama, Y.1    Muramatsu, H.2    Kamiya, T.3    McKee, A.4    Terashi, A.5
  • 22
    • 0024314677 scopus 로고
    • Effect of dichloroacetate on regional energy metabolites and pyruvate dehydrogenase activity during ischemia and reperfusion in gerbil brain
    • Katayama Y., Welsh F.A. Effect of dichloroacetate on regional energy metabolites and pyruvate dehydrogenase activity during ischemia and reperfusion in gerbil brain. J. Neurochem. 52:1989;1817-1822.
    • (1989) J. Neurochem. , vol.52 , pp. 1817-1822
    • Katayama, Y.1    Welsh, F.A.2
  • 25
    • 0023104271 scopus 로고
    • Multiple calcium channels and neuronal function
    • Miller R.J. Multiple calcium channels and neuronal function. Science. 235:1987;46-52.
    • (1987) Science , vol.235 , pp. 46-52
    • Miller, R.J.1
  • 26
    • 0027336413 scopus 로고
    • 2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils
    • 2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils. Brain Res. 613:1993;181-192.
    • (1993) Brain Res. , vol.613 , pp. 181-192
    • Nakamura, K.1    Hatakeyama, T.2    Furuta, S.3    Sakaki, S.4
  • 28
    • 0019377622 scopus 로고
    • Phosphorylation-dephosphorylation cycles and the regulation of fuel selection in mammals
    • W.R. Estabrook, P. Srere (Eds.) Academic Press, New York
    • P.J. Randle, Phosphorylation-dephosphorylation cycles and the regulation of fuel selection in mammals, in: W.R. Estabrook, P. Srere (Eds.), Current Topics in Cellular Regulation, Vol. 18, Academic Press, New York, 1981, pp. 107-129.
    • (1981) Current Topics in Cellular Regulation , vol.18 , pp. 107-129
    • Randle, P.J.1
  • 29
    • 0023258842 scopus 로고
    • Regional brain calcium changes in the rat middle cerebral artery occlusion model of ischemia
    • Rappaport Z.H., Young W., Flamm E. Regional brain calcium changes in the rat middle cerebral artery occlusion model of ischemia. Stroke. 18:1987;760-764.
    • (1987) Stroke , vol.18 , pp. 760-764
    • Rappaport, Z.H.1    Young, W.2    Flamm, E.3
  • 30
    • 0019348939 scopus 로고
    • Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle
    • W.R. Estabrook, P. Srere (Eds.) Academic Press, New York
    • L.J. Reed, Regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle, in: W.R. Estabrook, P. Srere (Eds.), Current Topics in Cellular Regulation, Vol. 18, Academic Press, New York, 1981, pp. 95-106.
    • (1981) Current Topics in Cellular Regulation , vol.18 , pp. 95-106
    • Reed, L.J.1
  • 31
    • 77956938088 scopus 로고
    • Pyruvate dehydrogenase
    • P.D. Boyer, E.G. Krebs (Eds.) Academic Press, New York
    • L. Reed, S.J. Yeaman, Pyruvate dehydrogenase, in: P.D. Boyer, E.G. Krebs (Eds.), The Enzymes, Vol. 18, Academic Press, New York, 1987, pp. 77-95.
    • (1987) The Enzymes , vol.18 , pp. 77-95
    • Reed, L.1    Yeaman, S.J.2
  • 32
    • 0019256564 scopus 로고
    • Excessive cellular acidosis: An important mechanism of neuronal damage in the brain?
    • Rehncrona S., Rosén I., Siesjö B.K. Excessive cellular acidosis: an important mechanism of neuronal damage in the brain? Acta Physiol. Scand. 110:1980;435-437.
    • (1980) Acta Physiol. Scand. , vol.110 , pp. 435-437
    • Rehncrona, S.1    Rosén, I.2    Siesjö, B.K.3
  • 33
    • 0019815904 scopus 로고
    • Brain lactic acidosis and ischemic cell damage: I. Biochemistry and neurophysiology
    • Rehncrona S., Rosén I., Siesjö B.K. Brain lactic acidosis and ischemic cell damage: I. Biochemistry and neurophysiology. J. Cereb. Blood Flow Metab. 1:1981;297-311.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 297-311
    • Rehncrona, S.1    Rosén, I.2    Siesjö, B.K.3
  • 34
    • 0019411915 scopus 로고
    • Brain extracellular ion composition and EEG activity following 10 minutes ischemia in normo- and hyperglycemic rats
    • Siemkowicz E., Hansen A.J. Brain extracellular ion composition and EEG activity following 10 minutes ischemia in normo- and hyperglycemic rats. Stroke. 12:1981;236-240.
    • (1981) Stroke , vol.12 , pp. 236-240
    • Siemkowicz, E.1    Hansen, A.J.2
  • 35
    • 0020631336 scopus 로고
    • Pyruvate dehydrogenase phosphate (PDHb) phosphatase in brain: Activity, properties, and subcellular localization
    • Sheu K.-F.R., Lai J.C.K., Blass J.P. Pyruvate dehydrogenase phosphate (PDHb) phosphatase in brain: activity, properties, and subcellular localization. J. Neurochem. 40:1983;1366-1372.
    • (1983) J. Neurochem. , vol.40 , pp. 1366-1372
    • Sheu, K.-F.R.1    Lai, J.C.K.2    Blass, J.P.3
  • 36
    • 0021366413 scopus 로고
    • Properties and regional distribution of pyruvate dehydrogenase kinase in rat brain
    • Sheu K.-F.R., Lai J.C.K., Blass J.P. Properties and regional distribution of pyruvate dehydrogenase kinase in rat brain. J. Neurochem. 42:1984;230-236.
    • (1984) J. Neurochem. , vol.42 , pp. 230-236
    • Sheu, K.-F.R.1    Lai, J.C.K.2    Blass, J.P.3
  • 37
    • 0023774654 scopus 로고
    • Mechanisms of ischemic brain damage
    • Siesjö B.K. Mechanisms of ischemic brain damage. Crit. Care Med. 16:1988;954-963.
    • (1988) Crit. Care Med. , vol.16 , pp. 954-963
    • Siesjö, B.K.1
  • 38
    • 0010588765 scopus 로고
    • Brain ischemia and cellular calcium homeostasis
    • T. Godfraindt (Ed.) Raven Press, New York
    • B.K. Siesjö, T. Wieloch, Brain ischemia and cellular calcium homeostasis, in: T. Godfraindt (Ed.), Calcium Entry Blockers and Tissue Protection, Raven Press, New York, 1985, pp. 139-149.
    • (1985) Calcium Entry Blockers and Tissue Protection , pp. 139-149
    • Siesjö, B.K.1    Wieloch, T.2
  • 39
    • 0026672262 scopus 로고
    • + in the hippocampus during recovery from short-term, transient ischemia
    • + in the hippocampus during recovery from short-term, transient ischemia. J. Cereb. Blood Flow Metab. 12:1992;759-772.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 759-772
    • Silver, I.A.1    Erecinska, M.2
  • 41
    • 0018419269 scopus 로고
    • Cerebrovascular effects of YC-93, a new vasodilator, in dogs, monkeys, and human patients
    • Takenaka T., Handa J. Cerebrovascular effects of YC-93, a new vasodilator, in dogs, monkeys, and human patients. Int. J. Clin. Pharmacol. Biophys. 17:1979;1-11.
    • (1979) Int. J. Clin. Pharmacol. Biophys. , vol.17 , pp. 1-11
    • Takenaka, T.1    Handa, J.2
  • 42
    • 0017089637 scopus 로고
    • Vasodilator profile of a new 1,4-dihydropyridine derivative, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)] ethyl ester 5-methyl ester hydrochloride (YC-93)
    • Takenaka T., Usuda S., Nomura T., Maeno H., Sado T. Vasodilator profile of a new 1,4-dihydropyridine derivative, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)] ethyl ester 5-methyl ester hydrochloride (YC-93). Arzeneim.-Forsch. 26:1976;2172-2178.
    • (1976) Arzeneim.-Forsch. , vol.26 , pp. 2172-2178
    • Takenaka, T.1    Usuda, S.2    Nomura, T.3    Maeno, H.4    Sado, T.5
  • 43
    • 0022888314 scopus 로고
    • Widespread distribution of dihydropyridine-sensitive calcium channels in the central nervous system
    • Thayer S.A., Murphy S.N., Miller R.J. Widespread distribution of dihydropyridine-sensitive calcium channels in the central nervous system. Mol. Pharmacol. 30:1986;505-509.
    • (1986) Mol. Pharmacol. , vol.30 , pp. 505-509
    • Thayer, S.A.1    Murphy, S.N.2    Miller, R.J.3
  • 44
    • 0021991451 scopus 로고
    • An N-methyl aspartate receptor-mediated synapse in rat cerebral cortex: A site of action of ketamine?
    • Thompson A.M., West D.C., Lodge D. An N-methyl aspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature. 313:1985;479-481.
    • (1985) Nature , vol.313 , pp. 479-481
    • Thompson, A.M.1    West, D.C.2    Lodge, D.3
  • 45
    • 0026022884 scopus 로고
    • Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage
    • Uematsu D., Araki N., Greenberg J.H., Sladky J., Reivich M. Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage. Neurology. 41:1991;88-94.
    • (1991) Neurology , vol.41 , pp. 88-94
    • Uematsu, D.1    Araki, N.2    Greenberg, J.H.3    Sladky, J.4    Reivich, M.5
  • 46
    • 0018976263 scopus 로고
    • Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat: II. Regional metabolic levels
    • Welsh F.A., Ginsberg M.D., Rieder W., Budd W.W. Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat: II. Regional metabolic levels. Stroke. 11:1980;355-363.
    • (1980) Stroke , vol.11 , pp. 355-363
    • Welsh, F.A.1    Ginsberg, M.D.2    Rieder, W.3    Budd, W.W.4
  • 48
    • 0028090533 scopus 로고
    • The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat
    • Zaidan E., Sims N.R. The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat. J. Neurochem. 63:1994;1812-1819.
    • (1994) J. Neurochem. , vol.63 , pp. 1812-1819
    • Zaidan, E.1    Sims, N.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.