An efficient synthesis of enantiomerically pure 2-[(2R)-arylmorpholin- 2-yl]ethanols, key intermediates of tachykinin receptor antagonist

Tetrahedron Asymmetry

Volumn 9, Issue 18, 1998, Pages 3251-3262

  Nishi, Takahide ^a   Ishibashi, Koki ^a   Nakajima, Katsuyoshi ^a   Iio, Yukiko ^a   Fukazawa, Tetsuya ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [(3,4 DICHLOROPHENYL)MORPHOLIN 2 YL]ETHANOL; 2 [(3,4 DIFLUOROPHENYL)MORPHOLIN 2 YL]ETHANOL; 2 [(4 CHLOROPHENYL)MORPHOLIN 2 YL]ETHANOL; 2 [(4 FLUOROPHENYL)MORPHOLIN 2 YL]ETHANOL; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; RECEPTOR AFFINITY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 0032544801     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(98)00336-X     Document Type: Article

References (14)

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