Single amino acid substitutions disrupt tetramer formation in the dihydroneopterin aldolase enzyme of Pneumocystis carinii

Biochemistry

Volumn 37, Issue 33, 1998, Pages 11629-11636

  Thomas, M Carmen ^a   Ballantine, Stuart P ^a   Bethell, Susanne S ^a   Bains, Satty ^a   Kellam, Paul ^a,b   Delves, Chris J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; FOLIC ACID; FRUCTOSE BISPHOSPHATE ALDOLASE; MUTANT PROTEIN; NEOPTERIN; RECOMBINANT ENZYME;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; NONHUMAN; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ALDEHYDE-LYASES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ASPARTIC ACID; CHROMATOGRAPHY, GEL; CROSS-LINKING REAGENTS; ESCHERICHIA COLI; FUNGAL PROTEINS; METHIONINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PNEUMOCYSTIS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; ULTRACENTRIFUGATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; PNEUMOCYSTIS CARINII;

EID: 0032544213     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980540x     Document Type: Article

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