Synthesis and structure-activity relationships of 7-(2- aminoalkyl)morpholinoquinolones as anti-helicobacter pylori agents

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 16, 1998, Pages 2185-2190

  Sakurai, Nobuhiro ^a   Sano, Mitsuharu ^a   Hirayama, Fumihiro ^a   Kuroda, Tsuyoshi ^a   Uemori, Satoru ^a   Moriguchi, Akihiko ^a   Yamamoto, Katsuhiro ^a   Ikeda, Yoshifumi ^a   Kawakita, Takeshi ^a  

^a Research Laboratories   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 CYCLOPROPYL 7 [2 (DIMETHYLAMINOMETHYL)MORPHOLINO] 6 FLUORO 1,4 DIHYDRO 8 METHOXY 4 OXO QUINOLINE 3 CARBOXYLIC ACID; 7 (2 AMINOALKYL)MORPHOLINOQUINOLONE DERIVATIVE; 7 (2 AMINOMETHYL 4 MORPHOLINYL) 1 CYCLOPROPYL 6,8 DIFLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; AMOXICILLIN; ANTIINFECTIVE AGENT; CLARITHROMYCIN; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TOSUFLOXACIN; UNCLASSIFIED DRUG; Y 34867;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STABILITY; DRUG SYNTHESIS; GERBIL; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION;

4-QUINOLONES; ANIMALS; ANTI-INFECTIVE AGENTS; DRUG STABILITY; FLUOROQUINOLONES; GERBILLINAE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; INDICATORS AND REAGENTS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NAPHTHYRIDINES; OFLOXACIN; QUINOLONES; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

ANIMALIA; GERBILLINAE; HELICOBACTER PYLORI; MERIONES UNGUICULATUS; NEGIBACTERIA;

EID: 0032544163     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00390-4     Document Type: Article

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