Biological properties of synthetic glycoconjugate mimics of heparin comprising different molecular spacers

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 16, 1998, Pages 2081-2086

  Dreef Tromp, C M ^a   Basten, J E M ^a   Broekhoven, M A ^a   Van Dinther, T G ^a   Petitou, M ^b   Van Boeckel, C A A ^a  

^a NV ORGANON   (Netherlands)

^b SANOFI   (France)

Author keywords

Antithrombotics; Carbohydrates; Glycosidation

Indexed keywords

BLOOD CLOTTING FACTOR 10A; GLYCOCONJUGATE; HEPARIN; THROMBIN;

ARTICLE; BINDING AFFINITY; HEPARINIZATION; INHIBITION KINETICS; METHYLATION; MOLECULAR MODEL; PROTEIN DOMAIN; THROMBOSIS PREVENTION;

ANTICOAGULANTS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; FACTOR XA; GLYCOCONJUGATES; HEPARIN; HUMANS; MOLECULAR SEQUENCE DATA; PLATELET FACTOR 4; POLYETHYLENE GLYCOLS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 0032544141     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00382-5     Document Type: Article

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