L-tryptophan urea amides as NK1/NK2 Dual antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 16, 1998, Pages 2259-2262

  Qi, Hongbo ^b   Shah, Shrenik K ^b   Cascieri, Margaret A ^a   Sadowski, Sharon J ^a   MaCcoss, Malcolm ^b  

^a Dept of Molec Pharmacol and B ^*  (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ A; SAREDUTANT; SUBSTANCE P; TACHYKININ RECEPTOR; TRYPTOPHAN; UREA DERIVATIVE;

AIRWAY CONSTRICTION; ARTICLE; ASTHMA; BINDING AFFINITY; BRONCHOSPASM; DRUG SYNTHESIS; MUCUS SECRETION; NEUROTRANSMITTER RELEASE; NONHUMAN; RECEPTOR AFFINITY;

AMIDES; DRUG DESIGN; HUMANS; INDICATORS AND REAGENTS; KINETICS; MOLECULAR STRUCTURE; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-2; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 0032544140     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00395-3     Document Type: Article

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