A bis(crown-ether) analogue of Troger's base: Recognition of achiral and chiral primary bisammonium salts

Tetrahedron Letters

Volumn 39, Issue 25, 1998, Pages 4565-4568

  Hansson, Anna P ^a   Norrby, Per Ola ^b   Wärnmark, Kenneth ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM DERIVATIVE; CROWN ETHER DERIVATIVE;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; MOLECULAR RECOGNITION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0032543485     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00807-7     Document Type: Article

References (35)

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34. 3 (1:1) at 25 °C. For each such pair of total concentrations, the expected concentrations of all species were calculated from a postulated set of association constants (eqs 1-3), whereupon the regression between the concentrations calculated and the shifts observed was calculated. The regression was optimized by varying the association constants. In direct measurements, 2.5-25 mM of 2 was combined with 2-100 mM of methylammonium chloride, yielding 75 shift differences. In the indirect measurements, 2.5-25 mM of 2 and 2.5-25 mM of bisammonium salt were buffered with methylammonium chloride to a constant chloride concentration of 74 mM, yielding ca. 100 measured shift differences in each case. The regression was optimized by varying the bisammonium association constant. Variations of the postulated constants by 10% led to a significantly diminished regression.
35. 20