ATP-dependent activation of the atrial acetylcholine-induced K+ channel does not require nucleoside diphosphate kinase activity

Circulation Research

Volumn 82, Issue 9, 1998, Pages 971-979

  Sorota, Steve ^a   Chlenov, Michael ^b   Du, Xiao Yi ^a   Kagan, Michael ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b PFIZER INC   (United States)

Author keywords

Acetylcholine induced K+ channel; Adenylylimidodiphosphate; ATP; Atrial myocyte; Nucleoside diphosphate kinase

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; NUCLEOSIDE DIPHOSPHATE KINASE;

ANIMAL CELL; ARTICLE; BINDING SITE; DOG; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM MUSCLE; HEART CONDUCTION; HEART MUSCLE CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY;

EID: 0032543281     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.9.971     Document Type: Article

References (26)

1. Soejima M, Noma A. Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in atrial cells. Pflugers Arch. 1984;400:424-431.
2. Sorota S, Tsuji Y, Tajima T, Pappano AJ. Pertussis toxin treatment blocks hyperpolarization by muscarinic agonists in chick atrium. Circ Res. 1985; 57:748-758.
3. k. Science. 1987;235:207-211.
4. Cerbai E, Klöckner U, Isenberg G. The α subunit of the GTP binding protein activates muscarinic potassium channels of the atrium. Science. 1988;240:1782-1783.
5. + channel in heart. Nature. 1987;325:321-326.
6. Nair LA, Inglese J, Stoffel R, Koch WJ, Lefkowitz RJ, Kwatra MM, Grant AO. Cardiac muscarinic potassium channel activity is attenuated by inhibitors of Gββ Circ Res. 1995;76:832-838.
7. Wickman KD, Iñiguez-Lluhl JA, Davenport PA, Taussig R, Krapivinsky GB, Linder ME, Gilman AG, Clapham DE. Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel. Nature. 1994;368:255-257.
8. Slesinger PA, Reuveny E, Jan YN, Jan LY. Identification of structural elements involved in G protein gating of the GIRK1 potassium channel. Neuron. 1995;15:1145-1156.
9. + channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins. Pflugers Arch. 1986;407:264-274.
10. + channel activation as revealed by hydrolysis-resistant GTP analogues. J Gen Physiol. 1988;91:469-493.
11. Gilman AG. G proteins: transducers of receptor-generated signals. Annu Rev Biochem. 1987;56:615-649.
12. + channels in the absence of agonists and G-nucleotides. Pflugers Arch. 1990;416:213-215.
13. + channels in rabbit atrium. J Physiol (Lond). 1991;433:589-613.
14. + channel activity in guinea-pig atrial cells is supported by nucleoside diphosphate kinase. Pflugers Arch. 1993;422:316-324.
15. Otero AS, Breitwieser GE, Szabo G. Activation of muscarinic potassium currents by ATP-γS in atrial cells. Science. 1988;242:443-445.
16. Heidbüchel H, Callewaert G, Vereecke J, Carmeliet E. Membrane-bound nucleoside diphosphate kinase activity in atrial cells of frog, guinea pig, and human. Circ Res. 1992;71:808-820.
17. t, and RAS) are not activated directly by nucleoside diphosphate kinase. J Biol Chem. 1992;267:18182-18189.
18. + channel activation does not involve GTP formation. J Biol Chem. 1996;271:21120-21125.
19. Sorota S, Huffman BF. Role of G-proteins in the ACh-induced potassium current of canine atrial cells. Am J Physiol. 1989;257:H1516-H1522.
20. Harmill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391:85-100.
21. Fabiato A. Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol. 1988;157:378-417.
22. Du X-Y, Sorota S. Cardiac swelling-induced chloride current depolarizes canine atrial myocytes. Am J Physiol. 1997;272:H1904-H1916.
23. + channels in rabbit atrial myocytes. J Biol Chem. 1995;270:9289-9294.
24. + channel by a G-protein-independent mechanism. J Gen Physiol. 1996;108:381-391.
25. Clark RB. Adenylylimidodiphosphate: effect of contaminants on adenylate cyclase activity. J Cyclic Nucleotide Res. 1978;4:259-270.
26. + channel (GIRK1/GIRK4) expressed in oocytes. Am J Physiol. 1997;272:H195-H206.