Structural and kinetic characterization of an acyl transferase ribozyme

Journal of the American Chemical Society

Volumn 120, Issue 6, 1998, Pages 1151-1156

  Suga, Hiroaki ^a   Lohse, Peter A ^b   Szostak, Jack W ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c Phylos Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; MUTANT PROTEIN; RIBOZYME;

ARTICLE; BINDING KINETICS; CATALYSIS; COMPETITIVE INHIBITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; METAL BINDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS;

ACYLTRANSFERASES; BASE COMPOSITION; BASE SEQUENCE; BIOTINYLATION; DIRECTED MOLECULAR EVOLUTION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION; RNA, CATALYTIC; SEQUENCE ANALYSIS; TEMPLATES, GENETIC;

EID: 0032542574     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja972472s     Document Type: Article

References (2)

1. Hager, A. J.; Pollard, J. D.; Szostak, J. W. Chem. Biol. 1996, 3, 717-725.
2. Lorsch, J. R.; Szostak, J. W. Acc. Chem. Res 1996, 29, 103-110.