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Volumn 403, Issue 1-2, 1998, Pages 35-43

Atypical background somatic mutant frequencies at the HPRT locus in children and adults with down syndrome

Author keywords

Down syndrome; Hypoxanthine guanine phosphoribosyl transferase (HPRT); Mutant frequency

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0032540912     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00024-4     Document Type: Article
Times cited : (6)

References (38)
  • 1
    • 0028019398 scopus 로고
    • Microsatellite instability: Marker of a mutator phenotype in cancer
    • [1] L.A. Loeb, Microsatellite instability: marker of a mutator phenotype in cancer, Cancer Res. 54 (1994) 5059-5063.
    • (1994) Cancer Res. , vol.54 , pp. 5059-5063
    • Loeb, L.A.1
  • 2
    • 0027401607 scopus 로고
    • The multistep nature of cancer
    • [2] B. Vogelstein, K.W. Kinzler, The multistep nature of cancer, Trends Genet. 9 (4) (1993) 138-141.
    • (1993) Trends Genet. , vol.9 , Issue.4 , pp. 138-141
    • Vogelstein, B.1    Kinzler, K.W.2
  • 3
    • 0021179588 scopus 로고
    • Down syndrome and acute leukemia in children: A 10-year retrospective survey from children's cancer study group
    • [3] L.L. Robison, M.J. Nesbit, H.N. Sather, C. Level, N. Shahidi, A. Kennedy, D. Hammond, Down syndrome and acute leukemia in children: a 10-year retrospective survey from children's cancer study group, J. Pediatr. 105 (2) (1984) 235-242.
    • (1984) J. Pediatr. , vol.105 , Issue.2 , pp. 235-242
    • Robison, L.L.1    Nesbit, M.J.2    Sather, H.N.3    Level, C.4    Shahidi, N.5    Kennedy, A.6    Hammond, D.7
  • 4
    • 0027420675 scopus 로고
    • Trisomy 21 in childhood acute lymphoblastic leukemia: A pediatric oncology group study (8602)
    • [4] M. Watson, A. Carroll, J. Shuster, R.C. Steube, F. Borowitz, F. Behm, D. Pullen, V. Land, Trisomy 21 in childhood acute lymphoblastic leukemia: a pediatric oncology group study (8602), Blood 82 (1993) 3098-3102.
    • (1993) Blood , vol.82 , pp. 3098-3102
    • Watson, M.1    Carroll, A.2    Shuster, J.3    Steube, R.C.4    Borowitz, F.5    Behm, F.6    Pullen, D.7    Land, V.8
  • 5
    • 0028144303 scopus 로고
    • Defective G2 repair in Down syndrome: Effect of caffeine, adenosine and niacinamide in control and X-ray irradiated lymphocytes
    • [5] J. Pincheira, M. Rodriguez, M. Bravo, M.H. Navarette, J.F. Lopez-Saez, Defective G2 repair in Down syndrome: effect of caffeine, adenosine and niacinamide in control and X-ray irradiated lymphocytes, Clin. Genet. 45 (1994) 25-31.
    • (1994) Clin. Genet. , vol.45 , pp. 25-31
    • Pincheira, J.1    Rodriguez, M.2    Bravo, M.3    Navarette, M.H.4    Lopez-Saez, J.F.5
  • 6
    • 0342412296 scopus 로고
    • T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood
    • [6] R.J. Albertini, K.L. Castle, W.R. Borcherding, T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood, Proc. Natl. Acad. Sci. U.S.A. 79 (1982) 6617-6621.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 6617-6621
    • Albertini, R.J.1    Castle, K.L.2    Borcherding, W.R.3
  • 9
    • 0027255852 scopus 로고
    • Analysis of mutations occurring at the human HPRT locus
    • [9] N.F. Cariello, T.R. Skopek, Analysis of mutations occurring at the human HPRT locus, J. Mol. Biol. 231 (1993) 41-57.
    • (1993) J. Mol. Biol. , vol.231 , pp. 41-57
    • Cariello, N.F.1    Skopek, T.R.2
  • 10
    • 0027176421 scopus 로고
    • In vivo mutation at the human HPRT locus
    • [10] N.F. Cariello, T.R. Skopek, In vivo mutation at the human HPRT locus, Trends Genet. 9 (9) (1993) 322-326.
    • (1993) Trends Genet. , vol.9 , Issue.9 , pp. 322-326
    • Cariello, N.F.1    Skopek, T.R.2
  • 13
    • 0030908438 scopus 로고    scopus 로고
    • The effects of maternal cigarette smoke exposure on somatic mutant frequencies at the HPRT locus in healthy newborns
    • [13] B.A. Finette, T. Poseno, P.M. Vacek, R.J. Albertini, The effects of maternal cigarette smoke exposure on somatic mutant frequencies at the HPRT locus in healthy newborns, Mutat. Res. 377 (1997) 115-123.
    • (1997) Mutat. Res. , vol.377 , pp. 115-123
    • Finette, B.A.1    Poseno, T.2    Vacek, P.M.3    Albertini, R.J.4
  • 14
    • 0025017202 scopus 로고
    • In vivo HPRT mutant frequencies in T-cells of normal human newborns
    • [14] M.J. McGinniss, M.T. Falta, L.S. Sullivan, R.J. Albertini, In vivo HPRT mutant frequencies in T-cells of normal human newborns, Mutat. Res. 240 (1990) 117-126.
    • (1990) Mutat. Res. , vol.240 , pp. 117-126
    • McGinniss, M.J.1    Falta, M.T.2    Sullivan, L.S.3    Albertini, R.J.4
  • 15
    • 0028147748 scopus 로고
    • Determination of HPRT mutant frequencies in T-lymphocytes from a healthy pediatric population: Statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age
    • [15] B.A. Finette, L.M. Sullivan, J.P. O'Neil, J.A. Nicklas, P.M. Vacek, R.J. Albertini, Determination of HPRT mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age, Mutat. Res. 308 (1994) 223-231.
    • (1994) Mutat. Res. , vol.308 , pp. 223-231
    • Finette, B.A.1    Sullivan, L.M.2    O'Neil, J.P.3    Nicklas, J.A.4    Vacek, P.M.5    Albertini, R.J.6
  • 17
    • 0023131909 scopus 로고
    • Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans
    • [17] J.P. O'Neill, M.J. McGinniss, J.K. Berman, L.M. Sullivan, J.A. Nicklas, R.J. Albertini, Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans, Mutagenesis, 1987, pp. 87-92.
    • (1987) Mutagenesis , pp. 87-92
    • O'Neill, J.P.1    McGinniss, M.J.2    Berman, J.K.3    Sullivan, L.M.4    Nicklas, J.A.5    Albertini, R.J.6
  • 18
    • 0022548615 scopus 로고
    • Detection of somatic mutations in man: Evaluation of the microtiter cloning assay for T-lymphocytes
    • [18] L. Henderson, J. Cole, H. Cole, S.E. James, M. Green, Detection of somatic mutations in man: evaluation of the microtiter cloning assay for T-lymphocytes, Mutagenesis 1 (1986) 195-200.
    • (1986) Mutagenesis , vol.1 , pp. 195-200
    • Henderson, L.1    Cole, J.2    Cole, H.3    James, S.E.4    Green, M.5
  • 19
    • 0028047414 scopus 로고
    • Elevated frequencies of HPRT mutant lymphocytes in cigarette-smoking mothers and their newborns
    • [19] M.M. Ammenheuser, A.B. Berenson, N.J. Stiglich, E.B. Whorton, J.B. Ward, Elevated frequencies of HPRT mutant lymphocytes in cigarette-smoking mothers and their newborns, Mutat. Res. 304 (1994) 285-294.
    • (1994) Mutat. Res. , vol.304 , pp. 285-294
    • Ammenheuser, M.M.1    Berenson, A.B.2    Stiglich, N.J.3    Whorton, E.B.4    Ward, J.B.5
  • 20
    • 0010527756 scopus 로고
    • Defective in vitro hematopoiesis in patients with Down Syndrome
    • Abstract
    • [20] A.C. Homans, J.L. Cohen, E.M. Mazur, Defective in vitro hematopoiesis in patients with Down Syndrome, Pediatr. Res. 25 (125A) (1989) Abstract.
    • (1989) Pediatr. Res. , vol.25 , Issue.125 A
    • Homans, A.C.1    Cohen, J.L.2    Mazur, E.M.3
  • 21
    • 0022572635 scopus 로고
    • Abnormalities of the in vitro cellular and humoral responses to tetanus and influenza antigens with concomitant numerical alterations in lymphocyte subsets in Down syndrome (trisomy 21)
    • [21] P. Ramila, A.C. Berger, N.H. McManus, N.H. Warner, M.A. Peacock, L.B. Epstein, Abnormalities of the in vitro cellular and humoral responses to tetanus and influenza antigens with concomitant numerical alterations in lymphocyte subsets in Down syndrome (trisomy 21), J. Immunol. 136 (5) (1986) 1661-1667.
    • (1986) J. Immunol. , vol.136 , Issue.5 , pp. 1661-1667
    • Ramila, P.1    Berger, A.C.2    McManus, N.H.3    Warner, N.H.4    Peacock, M.A.5    Epstein, L.B.6
  • 22
    • 0018838493 scopus 로고
    • T-lymphocyte function and sensitivity to interferon in trisomy 21
    • [22] L.B. Epstein, C.J. Epstein, T-lymphocyte function and sensitivity to interferon in trisomy 21, Cell. Immunol. 51 (1980) 303.
    • (1980) Cell. Immunol. , vol.51 , pp. 303
    • Epstein, L.B.1    Epstein, C.J.2
  • 23
    • 0016804731 scopus 로고
    • Derangements of immunoglobulin levels, phytohemagglutinin responsiveness and T and B cell markers in Down's syndrome at different ages
    • [23] G.R. Burgio, A.G. Ugazio, L. Nespoli, A.F. Marcioni, A.M. Bottelli, F. Pasquali, Derangements of immunoglobulin levels, phytohemagglutinin responsiveness and T and B cell markers in Down's syndrome at different ages, Eur. J. Immunol. 5 (1975) 600-603.
    • (1975) Eur. J. Immunol. , vol.5 , pp. 600-603
    • Burgio, G.R.1    Ugazio, A.G.2    Nespoli, L.3    Marcioni, A.F.4    Bottelli, A.M.5    Pasquali, F.6
  • 27
    • 0028839912 scopus 로고
    • Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: Implications for Down syndrome
    • [27] M. Peled-Kamar, J. Lotem, E. Okon, L. Sachs, Y. Groner, Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome, EMBO J. 14 (20) (1995) 4985-4993.
    • (1995) EMBO J. , vol.14 , Issue.20 , pp. 4985-4993
    • Peled-Kamar, M.1    Lotem, J.2    Okon, E.3    Sachs, L.4    Groner, Y.5
  • 28
    • 0029417023 scopus 로고
    • Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
    • [28] J. Busciglio, B.A. Yankner, Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro, Nature 378 (1995) 776-779.
    • (1995) Nature , vol.378 , pp. 776-779
    • Busciglio, J.1    Yankner, B.A.2
  • 30
    • 0019972481 scopus 로고
    • Bleomycin-induced chromosomal aberrations in Down's syndrome lymphocytes
    • [30] Vijayalaxmi, H.J. Evans, Bleomycin-induced chromosomal aberrations in Down's syndrome lymphocytes, Mutat. Res. 105 (1982) 107-113.
    • (1982) Mutat. Res. , vol.105 , pp. 107-113
    • Vijayalaxmi1    Evans, H.J.2
  • 31
    • 0014917356 scopus 로고
    • Chromosome constitution and its bearing on the chromosomal radiosensitivity in man
    • [31] M.S. Sasaki, A. Tonomura, S. Matsubara, Chromosome constitution and its bearing on the chromosomal radiosensitivity in man, Mutat. Res. 10 (1970) 617-633.
    • (1970) Mutat. Res. , vol.10 , pp. 617-633
    • Sasaki, M.S.1    Tonomura, A.2    Matsubara, S.3
  • 32
    • 0026556179 scopus 로고
    • The effect of aging on cell-cycle kinetics and X-ray induced chromosome aberrations in cultured lymphocytes from patients with Down syndrome
    • [32] T. Takeshita, C. Ariizumi-Shibusawa, H.H.K. Shimizu, S.I.Z. Yamagata, A. Asaka, M. Higurashi, The effect of aging on cell-cycle kinetics and X-ray induced chromosome aberrations in cultured lymphocytes from patients with Down syndrome, Mutat. Res. 275 (1992) 21-29.
    • (1992) Mutat. Res. , vol.275 , pp. 21-29
    • Takeshita, T.1    Ariizumi-Shibusawa, C.2    Shimizu, H.H.K.3    Yamagata, S.I.Z.4    Asaka, A.5    Higurashi, M.6
  • 33
    • 0023950507 scopus 로고
    • Effects of bleomycin on Down's syndrome lymphocytes in culture
    • [33] P. Gadhia, M. Gadhia, H. Zankl, Effects of bleomycin on Down's syndrome lymphocytes in culture, Mutat. Res. 207 (1988) 153-158.
    • (1988) Mutat. Res. , vol.207 , pp. 153-158
    • Gadhia, P.1    Gadhia, M.2    Zankl, H.3
  • 34
    • 0021322006 scopus 로고
    • Bleomycin-induced chromosomal aberrations and sister chromatid exchanges in Down lymphocyte cultures
    • [34] K. Iilima, K. Morimoto, A. Koizumi, M. Higurashi, M. Hirayama, Bleomycin-induced chromosomal aberrations and sister chromatid exchanges in Down lymphocyte cultures, Hum. Genet. 66 (1984) 57-61.
    • (1984) Hum. Genet. , vol.66 , pp. 57-61
    • Iilima, K.1    Morimoto, K.2    Koizumi, A.3    Higurashi, M.4    Hirayama, M.5
  • 35
    • 0023864368 scopus 로고
    • Chromosomal radiosensitivity of Down syndrome lymphocytes at different stages of the cell cycle
    • [35] H.M. Shafik, W.W. Au, M.S. Legator, Chromosomal radiosensitivity of Down syndrome lymphocytes at different stages of the cell cycle, Hum. Genet. 78 (1988) 71-75.
    • (1988) Hum. Genet. , vol.78 , pp. 71-75
    • Shafik, H.M.1    Au, W.W.2    Legator, M.S.3
  • 36
    • 0027477644 scopus 로고
    • Chromosomal breakpoints in irradiated and ethyl methane sulphonate-treated leukocytes of patients with Down syndrome
    • [36] T.C. Reeja, N. Chandra, K.M. Marimuthu, Chromosomal breakpoints in irradiated and ethyl methane sulphonate-treated leukocytes of patients with Down syndrome, Indian J. Exp. Biol. 31 (1993) 201-205.
    • (1993) Indian J. Exp. Biol. , vol.31 , pp. 201-205
    • Reeja, T.C.1    Chandra, N.2    Marimuthu, K.M.3
  • 37
    • 0028068517 scopus 로고
    • Adaptive response to ionizing radiation in norma and aneuploid human lymphocytes
    • [37] I. Kalina, H. Knonecna, G. Nemethova, N. Racekova, Adaptive response to ionizing radiation in norma and aneuploid human lymphocytes, Folia Biol. 40 (3) (1994) 119-123.
    • (1994) Folia Biol. , vol.40 , Issue.3 , pp. 119-123
    • Kalina, I.1    Knonecna, H.2    Nemethova, G.3    Racekova, N.4
  • 38
    • 0029923508 scopus 로고    scopus 로고
    • V(D)J recombinase-mediated HPRT mutations in peripheral blood lymphocytes of normal children
    • [38] B.A. Finette, T. Poseno, R.J. Albertini, V(D)J recombinase-mediated HPRT mutations in peripheral blood lymphocytes of normal children, Cancer Res. 56 (1996) 1405-1412.
    • (1996) Cancer Res. , vol.56 , pp. 1405-1412
    • Finette, B.A.1    Poseno, T.2    Albertini, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.