An enzymatically active chimeric HIV-1 reverse transcriptase (RT) with the RNase-H domain of murine leukemia virus RT exists as a monomer

Journal of Biological Chemistry

Volumn 273, Issue 16, 1998, Pages 9785-9789

  Misra, Hari S ^a   Pandey, Pradeep K ^a   Pandey, Virendra N ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; RIBONUCLEASE; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MOLONEY MURINE LEUKEMIA VIRUS; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE H, CALF THYMUS; RNA-DIRECTED DNA POLYMERASE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032540238     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.16.9785     Document Type: Article

References (24)

1. Di Marzo Veronese, F., Copeland, T. D., DeVico, A. L., Rahman, R., Oroszlan, Gallo, R. C., and Sarangadharan, M. G. (1986) Science 231, 1289-1291
2. Wondrak, E. M., Lower, J., and Kurth, R. J. (1986) Gen. Virol. 67, 2791-2797
3. Lightfoote, M. M., Coligan, J. E., Folks, T. M., Fauci, A. S., Martin, M. A., and Venkatesan, S. (1986) J. Virol. 60, 771-775
4. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., and Steitz, T. A. (1992) Science 256, 1783-1790
5. Wang, J., Smerdon, S. J., Jager, J., Kohlstaedt, L. A., Rice, P. A., Friedman, J. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7242-7246
6. Maxam, A., and Gilbert, W. (1980) Methods Enzymol. 65, 499-560
7. Pandey, V. N., Kaushik, N., Rege, N., Sarafianos, S. G., Yadav, P. N. S., and Modak, M. J. (1996) Biochemistry 35, 2168-2179
8. Kaushik, N., Rege, N., Sarafianos, S. G., Yadav, P. N. S., Modak, M. J., and Pandey, V. N. (1996) Biochemistry 35, 11536-11546
9. Kaushik, N., Harris, D., Rege, N., Modak, M. J., Yadav, P. N. S., and Pandey, V. N. (1997) Biochemistry 36, 14430-14438
10. Chowdhury, K., Kaushik, N., Pandey, V. N., and Modak. M. J. (1996) Biochemistry 35, 16610-16620
11. Lee, R., Kaushik, N., Modak, M. J., Vinayak, R., and Pandey, V. N. (1998) Biochemistry 37, 900-910
12. Kaushik, N., Pandey, V. N., and Modak, M. J. (1966) Biochemistry 35, 7256-7266
13. Saiki, R. K., Scharf, S. J., Faloona, Mullis, K. B., Horn, G. T., Ehrlich, H. A., and Arnheim, N. (1985) Science 230, 1350-1354
14. Sarafianos, S. G., Pandey, V. N., Kaushik, N., and Modak, M. J. (1995) Biochemistry 34, 7207-7216
15. Sarafianos, S. G., Pandey, V. N., Kaushik, N., and Modak, M. J. (1995) J. Biol. Chem. 270, 19729-19735
16. Richter. N. J., Howard, K. J., Cirino. N. M., Wohrl, B. M., and Le Grice, S. F. J. (1992) J. Biol. Chem. 267, 15952-15957
17. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
18. Modak, M. J., and Marcus, S. L. (1977) J. Biol. Chem. 252, 11-19
19. Wöhrl, B. M., Krebs, R., Thrall, S. H., Le Grice, S. F. J., Scheidig, A. J., and Goody, R. S. (1997) J. Biol. Chem. 28, 17581-17587
20. Telesnitsky, A., and Goff, S. P. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1276-1280
21. Hizi, A., Hughes, S. H., and Shaharabany, M. (1990) Virology 175, 575-580
22. Post, K., Guo, J., Kalman, E. Ucchida, T., Crouch, R. J., Levin, J. G. (1993) Biochemistry 32, 5508-5517
23. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H., and Arnold, E. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6320-6324
24. Jonckheere, H. Taymans, J. M., Balzarini, J., Velazquez, S., Camarasa, M. J., Desmyter, J., De Clercq, E., and Anne, J. (1994) J. Biol. Chem. 269, 25255-25258