X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 6, 1998, Pages 653-658

  Quéré, Luc ^a,c   Longfils, Géraldine ^a   Boigegrain, Robert ^b   Labeeuw, Bernard ^b   Gully, Danielle ^b   Durant, François ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b SANOFI   (France)

^c UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 (2,6 DIMETHOXYPHENYL) 1 [4 [N (3 DIMETHYLAMINOPROPYL) N METHYLCARBAMOYL] 2 ISOPROPYLPHENYL] 1H PYRAZOL 3 YLCARBONYLAMINO]ADAMANTANE 2 CARBOXYLIC ACID; 2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; LEVOCABASTINE; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CONFORMATIONAL TRANSITION; DRUG STRUCTURE; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; MICE; MODELS, MOLECULAR; PIPERIDINES; PROTEIN CONFORMATION; PYRAZOLES; QUINOLINES; RATS; RECEPTORS, NEUROTENSIN;

EID: 0032539790     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00087-0     Document Type: Article

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