A new type of cytokine receptor antagonist directly targeting gp130

Journal of Biological Chemistry

Volumn 273, Issue 42, 1998, Pages 27213-27219

  Renné, Christoph ^b   Kallen, Karl Josef ^b   Müllberg, Jürgen ^b   Jostock, Thomas ^b   Grötzinger, Joachim ^a,b   Rose John, Stefan ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOTROPHIN 1; CILIARY NEUROTROPHIC FACTOR; GLYCOPROTEIN GP 130; INTERLEUKIN 11; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; INTERLEUKIN 6 RECEPTOR; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR; ONCOSTATIN M; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; BINDING SITE; CONCENTRATION RESPONSE; CYTOKINE RELEASE; DISEASE ASSOCIATION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; MULTIPLE MYELOMA; POINT MUTATION; PRIORITY JOURNAL; PROTEIN TARGETING; RECEPTOR BINDING; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

ANTIGENS, CD; CILIARY NEUROTROPHIC FACTOR; CYTOKINE RECEPTOR GP130; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH INHIBITORS; HUMANS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LYMPHOKINES; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; ONCOSTATIN M; PEPTIDES; POINT MUTATION; PROTEIN BINDING; RECEPTORS, INTERLEUKIN-6; RECOMBINANT FUSION PROTEINS;

EID: 0032538553     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.42.27213     Document Type: Article

References (43)

1. Bazan, J. F. (1990) Immunol. Today 11, 350-354
2. Taga, T., and Kishimoto, T. (1997) Annu. Rev. Immunol. 15, 797-819
3. Mosley, B., De Imus, C., Friend, D., Boiani, N., Thoma, B., Park, L. S., and Cosman, D. (1996) J. Biol. Chem. 271, 32635-32643
4. Ichihara, M., Hara, T., Kim, H., Murate, T., and Miyajima, A. (1997) Blood 90, 165-173
5. Akira, S., Taga, T., and Kishimoto, T. (1993) Adv. Immunol. 54, 1-78
6. Kallen, K.-J., Meyer zum Büschenfelde, K. H., and Rose-John, S. (1997) Exp. Opin. Invest. Drugs 6, 237-266
7. Klein, B., Wijdenes, J., Zhang, X. G., Jourdan, M., Boiron, J. M., Brochier, J., Liautard, J., Merlin, M., Clement, C., Morel Fournier, B., Liu, Z. Y., Mannoni, P., Sany, J., and Bataille, R. (1991) Blood 78, 1198-1204
8. Wendling, D., Racadot, E., and Wijdenes, J. (1993) J. Rheumatol. 20, 259-262
9. Castell, J., Klapproth, J., Gross, V., Walter, E., Andus, T., Snyers, L., Content, J., and Heinrich, P. C. (1990) Eur. J. Biochem. 189, 113-118
10. Brakenhoff, J. P., de Hon, F. D., Fontaine, V., ten Boekel, E., Schooltink, H., Rose-John, S., Heinrich, P. C., Content, J., and Aarden, L. A. (1994) J. Biol. Chem. 269, 86-93
11. Ehlers, M., Grötzinger, J., de Hon, F. D., Müllberg, J., Brakenhoff, J. P., Liu, J., Wollmer, A., and Rose-John, S. (1994) J. Immunol. 153, 1744-1753
12. Savino, R., Lahm, A., Salvati, A. L., Ciapponi, L., Sporeno, E., Altamura, S., Paonessa, G., Toniatti, C., and Ciliberto, G. (1994) EMBO J. 13, 1357-1367
13. de Hon, F. D., Ehlers, M., Rose-John, S., Ebeling, S. B., Bos, H. K., Aarden, L. A, and Brakenhoff, J. P. (1994) J. Exp. Med. 180, 2395-2400
14. Savino, R., Ciapponi, L., Lahm, A., Demartis, A., Cabibbo, A., Toniatti, C., Delmastro, P., Altamura, S., and Ciliberto, G. (1994) EMBO J. 13, 5863-5870
15. Ehlers, M., de Hon, F. D., Bos, H. K., Horsten, U., Kurapkat, G., van De Leur, H. S., Grötzinger, J., Wollmer, A., Brakenhoff, J. P., and Rose-John, S. (1995) J. Biol. Chem. 270, 8158-8163
16. Zhang, X. G., Gu, J. J., Lu, Z. Y., Yasukawa, K., Yancopoulos, G. D., Turner, K., Shoyab, M., Taga, T., Kishimoto, T., Bataille, R., and Klein B. (1994) J. Exp. Med. 179, 1337-1342
17. Sporeno, E., Savino, R., Ciapponi, L., Paonessa, G., Cabibbo, A., Lahm, A., Pulkki, K., Sun, R. X., Toniatti, C., Klein, B., and Ciliberto, G. (1996)Blood 87, 4510-4519
18. Davis, S., Aldrich, T. H., Ip, N. Y, Stahl, N., Scherer, S., Farruggella, T., DiStefano, P. S., Curtis, R., Panayotatos, N., Gascan, H., Chevalier, S., and Yancopoulos, G. D. (1993) Science 259, 1736-1739
19. Müllberg, J., Schooltink, H., Stoyan, T., Gunther, M., Graeve, L., Buse, G., Mackiewicz, A., Heinrich, P. C., and Rose-John, S. (1993) Eur. J. Immunol. 23, 473-480
20. Baumann, H., Wang, Y., Morella, K. K., Lai, C. F., Dams, H., Hilton, D. J., Hawley, R. G., and Mackiewicz, A. (1996) J. Immunol. 157, 284-290
21. Pennica, D., Arce, V., Swanson, T. A., Vejsada, R., Pollock, R. A., Armanini, M., Dudley, K., Phillips, H. S., Rosenthal, A., Kato, A. C., and Henderson, C. E. (1996) Neuron 17, 63-74
22. Rose-John, S., and Heinrich, P. C. (1994) Biochem. J. 300, 281-290
23. Peters, M., Schirmacher, P., Goldschmitt, J., Odenthal, M., Peschel, C., Dienes, H. P., Fattori, E., Ciliberto, G., Meyer zum Büschenfelde, K. H., and Rose-John, S. (1997) J. Exp. Med. 185, 755-766
24. Romano, M., Sironi, M., Toniatti, C., Polentarutti, N., Fruscella, P., Ghezzi, P., Faggioni, R., Luini, W., van Hinsbergh, V., Sozzani, S., Bussolino, F., Poli, V., Ciliberto, G., and Mantovani, A. (1997) Immunity 6, 315-325
25. Udagawa, N., Takahashi, N., Katagiri, T., Tamura, T., Wada, S., Findlay, D. M., Martin, T. J., Hirota, H., Taga, T., Kishimoto, T., and Suda, T. (1995) J. Exp. Med. 182, 1461-1468
26. März, P., Cheng, J.-C., Gadient, R. A., Patterson, P., Stoyan, T., Otten, U., and Rose-John, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3251-3256
27. Fischer, M., Goldschmitt, J., Peschel, C., Kallen, K. J., Brakenhoff, J. P. J., Wollmer, A., Grötzinger, J., and Rose-John, S. (1997) Nat. Biotechnol. 15, 142-145
28. Hirata, Y., Taga, T., Hibi, M., Nakano, N., Hirano, T., and Kishimoto, T. (1989) J. Immunol. 143, 2900-2906
29. Brakenhoff, J. F., Hart, M., De Groot, E. R., Di Padova, F., and Aarden, L. A. (1990) J. Immunol 145, 561-568
30. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
31. Ali, S. A., and Steinkasserer, A. (1995) BioTechniques 18, 746-750
32. Lopata, M. A., Cleveland, D. W., and Sollner-Webb, B. (1984) Nucleic Acids Res. 12, 5707-5717
33. Oppmann, B., Stoyan, T., Fischer, M., Voltz, N., März, P., and Rose-John, S. (1996) J. Immunol. Methods 195, 153-159
34. Ehlers, M., Grötzinger, J., Fischer, M., Bos, H. K., Brakenhoff, J. P. J., and Rose-John, S. (1996) J. Interferon Cytokine Res. 16, 569-576
35. Gauldie, J., Richards, C., Harnish, D., Lansdorp, P., and Baumann, H. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 7251-7255
36. Mackiewicz, A., Schooltink, H., Heinrich, P. C., and Rose-John, S. (1992) J. Immunol. 149, 2021-2027
37. Ciapponi, L., Graziani, R., Paonessa, G., Lahm, A., Ciliberto, G., and Savino, R. (1995) J. Biol. Chem. 270, 31249-31254
38. Deleted in proof
39. Debets, R., and Savelkoul, H. F. (1994) Immunol. Today 15, 455-458
40. Krebs, B., Griffin, H., Winter, G., and Rose-John, S. (1998) J. Biol. Chem. 273, 2858-2865
41. Peters, M., Jacobs, S., Ehlers, M., Vollmer, P., Müllberg, J., Wolf, E., Brem, G., Meyer zum Büschenfelde, K. H., and Rose-John, S. (1996) J. Exp. Med. 183, 1399-1406
42. Vernalis, A. B., Hudson, K. R., and Heath, J. K. (1997) J. Biol. Chem. 272, 26947-26952
43. Xu, G. Y., Yu, H. A., Hong, J., Stahl, M., McDonagh, T., Kay, L. E., and Cumming, D. A. (1997) J. Mol. Biol. 268, 468-481