Tachykinins mediate changes in ion transport in porcine jejunum through release of prostaglandins and neurotransmitters

Regulatory Peptides

Volumn 77, Issue 1-3, 1998, Pages 105-111

  Thorbøll, Jens E ^a   Bindslev, Niels ^b   Tindholdt, Tyge T ^a   Schmidt, Peter ^b   Christensen, Poul ^b   Skadhauge, Erik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

NKA; Short circuit current; SP; Ussing chamber

Indexed keywords

NEUROKININ A; NEUROTRANSMITTER; PIROXICAM; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; SUBSTANCE P; TACHYKININ; TETRODOTOXIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; ION CURRENT; ION TRANSPORT; JEJUNUM; MALE; MEDIATOR; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; SWINE;

ANIMALS; DINOPROSTONE; ELECTROPHYSIOLOGY; FEMALE; ION TRANSPORT; JEJUNUM; MALE; NEUROKININ A; NEUROTRANSMITTER AGENTS; PIROXICAM; PROSTAGLANDINS; SUBSTANCE P; SWINE; TACHYKININS; TETRODOTOXIN; VASOACTIVE INTESTINAL PEPTIDE;

SUIDAE;

EID: 0032538324     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(98)00106-2     Document Type: Article

References (37)

1. [1] Cooke HJ, Carey HV. Neural Regulation of intestinal ion transport. In: Lebenthal E, Duffey M, editors. Textbook of Secretory Diarrhea. New York: Raven Press, 1990:1-14.
2. [2] Timmermans JP, Scheuermann DW, Stach W, Adriaensen D, De Groodt Lasseel MH. Distinct distribution of CGRP-, enkephalin-, galanin-, neuromedin U-, neuropeptide Y-, somatostatin-, substance P-, VIP-and serotonin-containing neurons in the two submucosal ganglionic neural networks of the porcine small intestine. Cell Tissue Res 1990;260:367-79.
3. [3] Schmidt P, Poulsen SS, Rasmussen TN, Bersani M, Holst JJ. Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract. Peptides 1991;12:963-73.
4. [4] Otsuka M, Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol Rev 1993;73:229-308.
5. [5] Parsons AM, Seybold VS, Chandan R, Vogt J, Larson AA, Murray CR, Soldani G, Brown DR. Neurokinin receptors and mucosal ion transport in porcine jejunum. J Pharmacol Exp Ther 1992;261:1213-21.
6. [6] Miller ER, Ullrey DE. The pig as a model for human nutrition. Ann Rev Nutr 1987;7:361-82.
7. [7] Clauss W, Dantzer V, Skadhauge E. A low-salt diet facilitates Cl secretion in hen lower intestine. J Membr Biol 1988;102:83-96.
8. 2 using antibody with high specificity and Sephadex LH-20 micro-column for the separation of prostaglandins. Prostaglandins 1976;11:399-420.
9. [9] Fahrenkrug J, Schaffalitzky de Muckadell OB. Radioimmunoassay of vasoactive intestinal polypeptide (VIP) in plasma. J Lab Clin Med 1977;89:1379-88.
10. [10] Kiyohara T, Okuno M, Nakanishi T, Shinomura Y, Matsuzawa Y. Effect of endothelin 1 on ion transport in isolated rat colon. Gastroenterology 1993;104:1328-36.
11. [11] Robberecht P, Gourlet P, De Neef P, Woussen-Colle MC, Vandermeers-Piret MC, Vandermeers A, Christophe J. Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes: discovery of PACAP(6-38) as a potent antagonist. Eur J Biochem 1992;207:239-46.
12. [12] Gozes I, Meltzer E, Rubinrout S, Brenneman DE, Fridkin M. Vasoactive intestinal peptide potentiates sexual behavior: inhibition by novel antagonist. Endocrinology 1989;125:2945-9.
13. [13] Brown DR, Parsons AN, O'Grady SM. Substance P produces sodium and bicarbonate secretion in porcine jejunal mucosa through an action on enteric neurons. J Pharmacol Exp Ther 1992;261:1206-12.
14. [14] Thorbøll JE, Hansen MB, Skadhauge E. Functional characterisation of tachykinin receptors mediating ion transport in porcine jejunum. Gastroenterology 1995;108:A700.
15. [15] Leduc LE, Needleman P. Regional localization of prostacyclin and thromboxane synthesis in dog stomach and intestinal tract. J Pharmacol Exp Ther 1079;211:181-8.
16. [16] Lawson LD, Powell DW. Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components. Am J Physiol 1987;252:G783-90.
17. 2 in the epithelial and sub-epithelial layers of the rat intestine. Biochim Biophys Acta 1982;713:684-7.
18. [18] Craven PA, DeRubertis FR. Patterns of prostaglandin synthesis and degradationin in isolated superficial and proliferative colonic epithelial cells compared to residual colon. Prostaglandins 1983;26:583-604.
19. [19] DuBois RN, Awad J, Morrow J, Roberts LJ, Bishop PR. Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. J Clin Invest 1994;93:493-8.
20. [20] Eistetter HR, Church DJ, Mills A, Godfrey PP, Capponi AM, Brewster R, Schultz MF, Kawashima E, Arkinstall SJ. Recombinant bovine neurokinin-2 receptor stably expressed in Chinese hamster ovary cells couples to multiple signal transduction pathways. Cell Regul 1991;2:767-79.
21. [21] Rangachari PK, Prior T, McWade D. Epithelial and mucosal preparations from canine colon: Responses to substance P. J Pharmacol Exp Ther 1990;254:1076-83.
22. [22] Reddix RA, Cooke HJ. Neurokinin 1 receptors mediate substance P-induced changes in ion transport in guinea-pig ileum. Regul Pept 1992;39:215-25.
23. [23] Cooke HJ, Reddix RA. Neural regulation of intestinal electrolyte transport. In: Johnson LR, editor. Physiology of the Gastrointestinal Tract. New York: Raven Press, 1994:2083-132.
24. [24] Cox HM, Cuthbert AW. Secretory actions of vasoactive intestinal polypeptide, peptide histidine isoleucine and helodermin in rat small intestine: the effects of putative VIP antagonists upon VIP-induced ion secretion. Regul Pept 1989;26:127-35.
25. [25] Messell T, Marling H, Poulsen SS, Bersani M, Holst JJ. Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused porcine ileum. Regul Pept 1992;38:179-98.
26. [26] Reddix RA, Kuwahara A, Wallace L, Cooke HJ. Vasoactive intestinal polypeptide: a transmitter in submucous neurons mediating secretion in guinea-pig distal colon. J Pharmacol Exp Ther 1994;269:1124-9.
27. [27] Burleigh DE, Kirkham SE. Lack of effect of three putative vasoactive intestinal peptide receptor antagonists on vasoactive intestinal peptide-induced secretory responses in rat colon. Eur J Pharmacol 1993;249:239-42.
28. [28] Moody TW, Zia F, Draoui M, Brenneman DE, Fridkin M, Davidson A, Gozes I. A vasoactive intestinal peptide antagonist inhibits non-small cell lung cancer growth. Proc Natl Acad Sci USA 1993;90:4345-9.
29. [29] Christophe J. Type I receptors for PACAP (a neuropeptide even more important than VIP?). Biochim Biophys Acta 1993;1154:183-99.
30. [30] Tornøe K, Hannibal J, Fahrenkrug J, Holst JJ. PACAP-(1-38) as neurotransmitter in pig pancreas: receptor activation revealed by the antagonist PACAP-(6-38). Am J Physiol 1997;273:G436-46.
31. [31] Tien XY, Wallace LJ, Kachur JF, Won Kim S, Gaginella TS. Neurokinin A increases short-circuit current across rat colonic mucosa: a role for vasoactive intestinal polypeptide. J Physiol Lond 1991;437:341-50.
32. [32] Chandan R, Hildebrand KR, Seybold VS, Soldani G, Brown DR. Cholinergic neurons and muscarinic receptors regulate anion secretioin pig distal jejunum. Eur J Pharmacol 1991;193:265-73.
33. [33] Eberhart CE, Dubois RN. Eicosanoids and the gastrointestinal tract. Gastroenterology 1995;109:285-301.
34. [34] Mantyh CR, Gates TS, Zimmerman RP, Welton ML, Passaro EP, Vigna SR, Maggio JE, Kruger L, Mantyh PW Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc Natl Acad Sci USA 1988;85:3235-9.
35. [35] Pothoulakis C, Castagliuolo I, LaMont JT, Jaffer A, O'Keane VJ, Snider RM, Leeman SE. CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci USA 1994;91:947-51.
36. [36] Keränen U, Kiviluoto T, Järvinen H, Bäck N, Kivilaakso E, Soinila S. Changes in substance P-immunoreactive innervation of human colon associated with ulcerative colitis. Dig Dis Sci 1995;40:2250-8.
37. [37] Mantyh CR, Maggio JE, Mantyh PW, Vigna SR, Pappas TN. Increased substance P receptor expression by blood vessels and lymphoid aggregates in Clostridium difficile-induced pseudomembranous colitis. Dig Dis Sci 1996;41:614-20.