LDA-induced metalation of isoindolinones. An efficient route to 3- substituted isoindoline derivatives

Tetrahedron Letters

Volumn 39, Issue 16, 1998, Pages 2319-2320

  Couture, Axel ^a   Deniau, Eric ^a   Ionescu, Dumitru ^a   Grandclaudon, Pierre ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONAL GROUP; HETEROCYCLIC COMPOUND; ISOINDOLE DERIVATIVE; LITHIUM DERIVATIVE; METAL; TETRAHYDROFURAN;

ARTICLE; CHEMICAL REACTION; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0032537204     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00136-1     Document Type: Article

References (11)

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3. 3. Lenoir, J-Y.; Ribereau, P.; Quéguiner, G. Tetrahedron Lett. 1994, 34, 6283-6286.
4. 4. Clark, R. D.; Jahangir, A. Org. React. 1995, 47, 1-314.
5. 5. Kraus, G. A.; Sugimoto, H.; Tetrahedron Lett. 1978, 26, 2263-2266.
6. 6. Majundar, G; Pal, R.; Murty, K. N. S. N. J. Chem. Soc., Perkin Trans I 1994, 309-316.
7. 7. Anderson, P. S.; Christy, M. E.; Dylion Colton, C.; Halczenko, W.; Ponticello, G S.; Shepard, K. L. J. Org. Chem. 1979, 44, 1519-1533.
8. 8. Snieckus, V. Chem. Rev. 1990, 90, 879-973.
9. 13C NMR (DMSO-d6, 75 MHz) δ: 33.5, 72.0, 76.0, 127.4, 128.6, 131.5, 132.3, 132.9, 133.0, 135.5, 138.3, 146.0, 147.5, 173.0.
10. 10. Campbell, J. B.; Dedinas, R. F.; Trumbower-Walsh, S. A. J. Org. Chem. 1996, 61, 6205-6211.
11. 3, 75 MHz) δ: 55.3, 58.3, 60.0, 73.9, 75.9, 113.9, 122.5, 123.1, 126.0, 126.9, 127.0, 127.3, 127.7, 128.4, 128.5, 130.0, 158.8.