Spontaneous cAMP-dependent derepression of gene expression in stationary phase plays a role in recombinant expression instability

Gene

Volumn 209, Issue 1-2, 1998, Pages 95-103

  Grossman, Trudy H ^a   Kawasaki, Ernest S ^a   Punreddy, Sandhya R ^a   Osburne, Marcia S ^a  

^a Procept Inc   (United States)

Author keywords

lac operon regulation; Leaky gene expression; T7 expression vectors

Indexed keywords

ACETIC ACID; CYCLIC AMP; RNA POLYMERASE;

ARTICLE; BACTERIOPHAGE T7; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC STABILITY; LACTOSE OPERON; NONHUMAN; PLASMID; PRIORITY JOURNAL; RECOMBINANT GENE;

BACTERIOPHAGE T7; BETA-GALACTOSIDASE; CHROMOSOMES, BACTERIAL; CLONING, MOLECULAR; CYCLIC AMP; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; KINETICS; LAC OPERON; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; VIRAL PROTEINS;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0032536841     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00020-1     Document Type: Article

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