Development and biochemical characterization of a 2'-C-cyano-2'-deoxy-1-β-D-arabino-pentofuranosylcytosine (CNDAC)-resistant variant of the human fibrosarcoma cell line HT-1080

Cancer Letters

Volumn 123, Issue 1, 1998, Pages 53-61

  Obata, Tohru ^a   Endo, Yoshio ^a   Tanaka, Motohiro ^a   Matsuda, Akira ^b   Sasaki, Takuma ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

2' C cyano 2' deoxy 1 D arabino pentofuranosylcytosine; Deoxycytidine kinase; DNA synthesis inhibitor; Resistant cell

Indexed keywords

2' C CYANO 2' DEOXY 1 BETA D ARABINOPENTOFURANOSYLCYTOSINE; ANTINEOPLASTIC AGENT; CELL DNA; DEOXYCYTIDINE; DEOXYCYTIDINE KINASE; DRUG METABOLIZING ENZYME; MUTANT PROTEIN; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DNA INTERACTION; DRUG UPTAKE; ENZYME ACTIVITY; FIBROSARCOMA; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTIMETABOLITES, ANTINEOPLASTIC; CYTARABINE; DEOXYCYTIDINE KINASE; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; FIBROSARCOMA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES; HUMANS; RNA, NEOPLASM; TUMOR CELLS, CULTURED;

EID: 0032536185     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00402-3     Document Type: Article

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