O-(Fluoresceinylmethyl)hydroxylamine (OFMHA): A fluorescent reagent for detection of damaged nucleic acids

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 24, 1998, Pages 3599-3602

  Adamczyk, Maciej ^a   Mattingly, Phillip G ^a   Moore, Jeffrey A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (FLUORESCEINYLMETHYL)HYDROXYLAMINE; FLUORESCEIN; NUCLEIC ACID; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL BINDING; DIAGNOSTIC VALUE; DNA DAMAGE; FLUORESCENCE; NUCLEIC ACID ANALYSIS; REACTION ANALYSIS;

ANIMALS; CATTLE; DNA DAMAGE; FLUORESCEINS; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; SPECTROMETRY, FLUORESCENCE;

EID: 0032535593     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00658-1     Document Type: Article

References (10)

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7. 7. After our work on OFMHA was completed compound 6 and its use in labeling abasic sites on DNA were reported: Makrigiorgos, G. M.; Chakrabarti, S.; Mahmood, A. Int. J. Radiat. Biol. 1998, 74, 99. (formula presented)
8. 18; 30:65:5 AcCN/water/1% aq TFA] retention time 3.46 min, 96%.
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