SCID mice containing muscle with human mitochondrial DNA mutations. An animal model for mitochondrial DNA defects

Journal of Clinical Investigation

Volumn 102, Issue 12, 1998, Pages 2090-2095

  Clark, Kim M ^a   Watt, Diana J ^b   Lightowlers, Robert N ^a   Johnson, Margaret A ^a   Relvas, João B ^b   Taanman, Jan Willem ^c   Turnbull, Douglass M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Cultured cells; Heterologous transplantation; Mitochondria; Muscle fibers; Muscular diseases

Indexed keywords

MITOCHONDRIAL DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; GENE MUTATION; INFECTION RISK; MOUSE; MUSCLE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 0032535088     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI944     Document Type: Article

References (1)

1. Zillikens, D., P.A. Rose, S.D. Balding, Z. Liu, M. Olague-Marchan, L.A. Diaz, and G.J. Giudice. 1997. Tight clustering of extracellular BP180 epitopes recognized by bullous pemphigoid autoantibodies. J. Invest. Dermatol. 109:573-579.