Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: In vitro degradation and identification of residues required for proteolysis

Genes and Development

Volumn 12, Issue 24, 1998, Pages 3889-3899

  Gonzalez, Martín ^a   Frank, Ekaterina G ^a   Levine, Arthur S ^a   Woodgate, Roger ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

ATP dependent protease; Degradation signal; SOS mutagenesis; UmuD'

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; BACTERIAL PROTEIN; ENDOPEPTIDASE LA; PROTEIN UMUD; PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; ESCHERICHIA COLI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032535038     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.24.3889     Document Type: Article

References (10)

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8. Frank, E.G., J. Hauser, A.S. Levine, and R. Woodgate. 1993. Targeting of the UmuD, UmuD′ and MucA′ mutagenesis proteins to DNA by RecA protein. Pioc. Natl. Acad. Sci. 90: 8169-8173.
9. Frank, E.G., D.G. Ennis, M. Gonzalez, A.S. Levine, and R. Woodgate. 1996a. Regulation of SOS mutagenesis by proteolysis. Proc. Natl. Acad. Sci. 93: 10291-10296.
10. Frank, E.G., M. Gonzalez, D.G. Ennis, A.S. Levine, and R. Woodgate. 1996b. In vivo stability of the Umu mutagenesis proteins: A major role for RecA. J. Bacteriol. 178: 3550-3556.