Porcine recombinant dihydropyrimidine dehydrogenase: Comparison of the spectroscopic and catalytic properties of the wild-type and C671A mutant enzymes

Biochemistry

Volumn 37, Issue 50, 1998, Pages 17598-17609

  Rosenbaum, Katrin ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE;

ARTICLE; BINDING SITE; CATALYSIS; ENZYME ACTIVITY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PYRIMIDINE METABOLISM; SPECTROMETRY; SWINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SUIDAE; SUS SCROFA;

EID: 0032534879     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9815997     Document Type: Article

References (15)

1. Wasternack, C. (1980) Pharmacol. Ther. 8, 629-665.
2. Shiotani, T., and Weber, G. (1981) J. Biol. Chem. 256, 219-224.
3. Podschun, B., Wahler, G., and Schnackerz, K. D. (1989) Eur. J. Biochem. 185, 219-224.
4. Porter, D. J. T., Chestnut, W. G., Taylor, L. C. E., Merill, B. M., and Spector, T. (1991) J. Biol. Chem. 266, 19988-19994.
5. Lu, Z. H., Zhang, R., and Diasio, R. (1992) J. Biol. Chem. 267, 17102-17109.
6. Schmitt, U., Jahnke, K., Rosenbaum, K., Cook, P. F., and Schnackerz, K. D. (1996) Arch. Biochem. Biophys. 332, 175-182.
7. Yokota, H., Fernandez-Salguerno, P., Furuya, H., Lin, K., McBride, O. W., Podschun, B., Schnackerz, K. D., and Gonzalez, F. J. (1994) J. Biol. Chem. 269, 23192-23196.
8. Hull, W. E., Port, R. E., Hermann, R., Britsch, B., and Kunz, W. (1988) Cancer Res. 48, 1680-1688.
9. Okeda, R., Shibutani, M., Matsuo, T., Kuroiwa, T., Shimokawa, R., and Tajima, T. (1990) Acta Neuropathol. 81, 66-73.
10. Bakkeren, J. A. J. M., De Abreu, R. A., Sengers, R. C. A., Gabreels, F. J. M., Mass, J. M., and Renier, W. O. (1984) Clin. Chim. Acta 140, 247-256.
11. Vreken, P., van Kuilenburg, A. B. P., and Meinsma, R. (1996) J. Inherited Metab. Dis. 19, 645-646.
12. Vreken, P., van Kuilenburg, A. B. P., Meinsma, R., and van Gennip, A. H. (1997) J. Inherited Metab. Dis. 20, 335-338.
13. Tuchman, M., Stoeckeler, J. S., Kiang, D. T., O'Dea, R. F., Rammaraine, M. L., and Mirkin, B. L. (1985) N. Engl. J. Med. 313, 245-249.
14. Berger, R., Stoker-de Vries, S. A., Wadman, S. K., Duran, M., Beemer, F. A., de Bree, P. K., Weits-Binnerts, J. J., Penders, T. J., and van der Woude, J. K. (1984) Clin. Chim. Acta 141, 227-234.
15. Podschun, B., Cook, P. F., and Schnackerz, K. D. (1990) J. Biol. Chem. 265, 12966-12972.