Microglial activation induced by factor(s) contained in sera from Alzheimer-related ApoE genotypes

Journal of Neuroscience Research

Volumn 54, Issue 4, 1998, Pages 539-553

  Lombardi, Valter R M ^a   Garcia M ^a   Cacabelos, R ^a  

^a Centro de Investigacion Biomedica EuroEspes   (Spain)

Author keywords

AD; IL 1 ; MHC class I; MHC class II; Microglia

Indexed keywords

APOLIPOPROTEIN E; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADULT; AGED; AGING; ALLELE; ALZHEIMER DISEASE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FAMILY HISTORY; GENDER; GENETIC SUSCEPTIBILITY; GENOTYPE; HEAD INJURY; HUMAN; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; RAT; SCREENING TEST;

AGED; ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEINS E; CELL COUNT; CELL SIZE; CELLS, CULTURED; FLOW CYTOMETRY; GENOTYPE; HIPPOCAMPUS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MICROGLIA; MIDDLE AGED; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0032533730     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19981115)54:4<539::AID-JNR11>3.0.CO;2-Q     Document Type: Article

References (79)

1. Abdelbasset E, Fedoroff S (1995): Effect of bacterial wall lipopolysaccharide (LPS) on morphology, motility, and cytoskeletal organization of microglia in cultures. J Neurosci Res 41:222-237.
2. Akiyama H (1994): Inflammatory response in Alzheimer's disease. Tohoku J Exp Med 174:295-303.
3. Aihara N, Hall JJ, Pitts LH, Fakude K, Noble LJ (1995): Altered immunoexpression of microglia and macrophages after mild head injury. J Neurotrauma 12:53-63.
4. Angelov DN, Gunkel A, Stennert E, Neiss WF (1995): Phagocytic microglia during delayed neuronal loss in the facial nucleus of the rat: Time course of the neuronofugal migration of brain macrophages. Glia 13:113-129.
5. Araujo DM, Cotman CW (1992): Beta-amyloid stimulates glial cells in vitro to produce growth factor that accumulate in senile plaques in Alzheimer's disease. Brain Res 569:141-145.
6. Araujo DM, Lapchak PA (1994): Induction of immune system mediators in the hippocampal formation in Alzheimer's and Parkinson's diseases: Selective effects on specific interleukins and interleukin receptors. Neuroscience 61:745-754.
7. Argall KG, Armati PJ, Pollard JD (1994): A method for the isolation and culture of rat peripheral nerve vascular endothelial cells. Mol Cell Neurosci 5:413-417.
8. Arvin B, Neville LF, Barone FC, Feuerstein GZ (1995): Brain injury and inflammation. A putative role for TNF alfa. Ann NY Acad Sci 765:62-71.
9. 2+ i trasients and changes the organization of actin in microglia. Glia 11:336-344.
10. Banati RB, Graeber MB (1994): Surveillance, intervention and cytotoxicity: is there a protective role of microglia? Dev Neurosci 16:114-127.
11. Baszler TV, Zachary JF (1991): Murine retroviral neurovirulence correlates with an enhanced ability of virus to infect selectively, replicate in, and activate resident microglial cells. Am J Pathol 138:655-671.
12. Beal MF (1995): Aging, energy and oxidative stress in neurodegenerative diseases. Ann Neurol 38:357-366.
13. Benjamin R, Leake A, Edwardson JA, McKeith IG, Ince PG, Perry RH, Morris CM (1994):Protective effect of apoE ∈2 in Alzheimer's disease. Lancet 343:1565.
14. Bennett C (1995): Evidence that the ApoE locus influences rate of disease progression in late onset familial Alzheimer's disease but is not causative. Am J Med Genet 60:1-6.
15. Bhat NR, Zhang P (1996): Activation of mitogen-activated protein kinases in oligodendrocytes. J Neurochem 66:1986-1994.
16. Boller F, Saxton J (1990): Comparison of criteria for diagnosing Alzheimer's disease in the United States and Europe. Adv Neurol 51:1-5.
17. Boyle EA, McGeer PL (1990): Cellular immune response in multiple sclerosis plaques. Am J Pathobiol 137:575-584.
18. Bowman CL, Swann WS, Severin CM, Romanowski MR (1992): Co-cultures of microglia and astrocytes from kainic acid-lesioned adult rat hippocampus: Effects of glutamate. Glia 5:285-289.
19. Brewer GJ, Ashford JW (1992): Human serum stimulates Alzheimer markers in cultured hippocampal neuron. J Neurosci Res 33:355-369.
20. Browning PJ (1994): Apolipoprotein E, a novel heparin-binding protein inhibits the development of Kaposi's sarcoma-like lesions in BALB/c nu/nu mice. J Exp Med 180:1949-1954.
21. Cacabelos R (1991) "Alzheimer's Disease." Barcelona, Spain: Prous Science Publishers.
22. Cacabelos R (1996): Diagnosis of Alzheimer's disease: Defining genetic profiles genotype vs phenotype. Acta Neurol Scand 165:72-84.
23. Cacabelos R, Lao JI, Beyer K, Álvarez XA, Franco-Maside A (1996): A Genetic testing in Alzheimer's disease: ApoE genotyping and ethiopathogenic factors. Meth Find Exp Clin Pharmacol 18(suppl. A):161-179.
24. Chao CC (1994): Transforming growth factor-beta protects human neurons against beta-amyloid induced injury. Mol Chem Neuropathol 23:159-178.
25. Dahlström A, McRae A, Polinsky R, Nee L, Sadasivan B, Ling EA (1994): Alzheimer's disease cerebrospinal fluid antibodies display selectivity for microglia. Investigations with cell cultures and human cortices biopsies. Mol Neurobiol 9:41-54.
26. Davis ES, Foster TD, Thomas WE (1994): Cellular forms and functions of brain microglia. Brain Res Bull 34:73-78.
27. Dickson DW, Mattiace LA, Kure K, Hutchins K, Lyman WD, Brosnan CF (1991): Biology of disease. Microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab Invest 64:135-155.
28. Dickson DW, Lee SS, Mattiace LA, Yen SC, Brosnan C (1993): Microglia and cytokines in Neurological disease, with special references to AIDS and Alzheimer's disease. Glia 7:75-83.
29. DSM-IV (1994): "Diagnostic and Statistical Manual of Mental Disorders." Fourth Edition.Washington, DC: American Psychiatric Association.
30. Eikelenboom P, Zhan SS, van Gool WA, Allsop D (1994): Inflammatory mechanisms in Alzheimer's disease. Trends Pharm Sci 15:447-450.
31. Finsen BR, Jorgensen MB, Diemer NH, Zimmer J (1993): Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus. Glia 7:41-49.
32. Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J (1991). Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349:704-706.
33. Griffin WS, Sheng JG, Roberts GW, Mrak RE (1995): Interleukin-1 expression in different plaque type in Alzheimer's disease: Significance in plaque evolution. J Neuropathol Exp Neurol 54:276-281.
34. Guo C, Marynen P, Cassimann JJ (1993): A rapid semiautomated method for apolipoprotein E genotyping. PCR methods and applications. Cold Spring Harbor Laboratory 2:348-350.
35. Hauke C, Korr H (1993): RCA-I lectin histochemistry after trypsinisation enables the identification of microglial cells in thin paraffin sections of the mouse brain. J Neurosci Methods 50:273-277.
36. Hixson JE, Vernier DT (1990): Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha I. J Lipid Res 31:545-549.
37. Huell M, Strauss S, Volk B, Berger M, Bauer J (1995): Interleukin 6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol 89:544-551.
38. Kaur C, Wu CM, Wen CY, Ling EA (1994): The effects of subcutaneous injections of glucocorticoids on amoeboid microglia in postnatal rats. Arch Histol Cytol 57:449-459.
39. Korematsu K, Goto S, Nagahiro S, Ushio Y (1994): Microglial response to transient focal cerebral ischemia: an immunocytochemical study on the rat cerebral cortex using antiphosphotyrosine antibody. J Cereb Blood Flow Metab 14:825-830.
40. Korotzer A, Pike CJ, Cotman CW (1993): B-amyloid peptides induce degeneration of cultured rat microglia. Brain Res 624:121-125.
41. Lawson LJ, Perry VH, Dri P, Gordon S (1990): Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39:151-170.
42. Leach J, Levy R (1994): Reflections on the NINCDS/ADRDA criteria for the diagnosis of Alzheimer's disease. Int J Geriatr Psychiatry 9:173-179.
43. Lee GJ (1993): The possible contribution of microglia and macrophages to delayed neuronal death after ischemia. J Neurol Sci 114:119-122.
44. Lee SC, Liu W, Brosnan CF, Dickson DW (1992): Characterization of primary human fetal dissociated central mervous system cultures with an emphasis on microglia. Lab Invest 67:465-475.
45. Lehtimaki T (1995): Apolipoprotein E polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease. Hum Genet 95:39-42.
46. Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu C, Jondro PD, Schmidt SD, Wang K, Crowley AC, Fu YH, Guenette SY, Galas D, Nemens E, Wijsman EM, Bird TD, Schellemberg GD, Tanzi RE (1995): Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269:973-977.
47. Ling EA, Kaur C, Wong WC (1991): Expression of major histocompatibility complex and leukocyte common antigens in amoeboid microglia in postnatal rats. J Anat 177:117-126.
48. Ling EA, Dahlström A, Polinsky RJ, Nee LE, McRae A (1992): Studies of activated microglial cells and macrophages using Alzheimer's disease cerebrospinal fluid in adult rats with experimentally induced lesions. Neuroscience 5:815-825
49. Mackanzie IR, Hao C, Munoz DG (1995): Role of microglia in senile plaque formation. Neurobiol Aging 16:797-804.
50. McCarthy KD, De Vellis J (1980): Preparation of separate astroglial and oligodendroglial cultures from rat cerebral tissue. J Cell Biol 85:890-892.
51. McGeer PL, Itagaki S, Boyes BE, McGeer EG (1988): Reactive microglia are positive for HLA-DR in the substancia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38:1285-1291.
52. McGeer PL, Klegeris A, Walker DG, Yasuhara O, McGeer EG (1994): Pathological proteins in senile plaques. Tohoku J Exp Med 174:269-277.
53. McRae A, Ling EA, Polinsky R, Gottfries CG, Dahlström A (1991): Antibodies in the cerebrospinal fluid of some Alzheimer's disease patients recognize amoeboid microglial cells in the developing central nervous system. Neuroscience 41:739-752.
54. McRae A, Dahlström A, Polinsky R, Ling EA (1993): Cerebrospinal fluid microglial antibodies: Potential diagnostic markers for immune mechanisms in Alzheimer's disease. Behav Brain Res 57:225-234.
55. Meda L, Cassatella MA, Szendrei GI, Otvos L, Baron P, Villalba M, Ferrari D, Rossi F (1995): Activation of microglia cells by beta amyloid protein and interferon-gamma. Nature 374:647-650.
56. Morioka T, Baba T, Black KL, Streit WJ (1992a): Immunophenotypic analysis of infiltrating leukocytes and microglia in an experimental rat glioma. Acta Neuropathol 83:590-597.
57. Morioka T, Kalehua AN, Streit WJ (1992b): Progressive expression of immunomolecules on microglial cells in rat dorsal hippocampus following transient forebrain ischemia. Acta Neuropathol 83:149-157.
58. Palmen MJ, Dijkstra CD, van der Ende MB, Peña AS, van Rees EP (1995): Anti-CD11b/CD18 antibodies reduce inflammation in acute colitis rats. Clin Exp Immunol 101:351-356.
59. Pardridge WH, Buciak JL, Yang J, Miller BL, Vinters HV (1991): Measurement of amyloid peptide precursor of Alzheimer disease in human blood by double antibody immunoradiometric assay. Alzheimer Dis Assoc Disord 5:12-24.
60. Petite D, Calvet MC (1995): Cryopreserved neuronal cells in long-term cultures of dissociated rat cerebral cortex: Survival and morphometric characteristics as revealed by immunocytochemistry. Brain Res 669:263-274.
61. Popovich PG, Streit WJ, Stokes BT (1993): Differential expression of MHC class II antigen in the contused rat spinal cord. J Neurotrauma 10:37-46.
62. Rinaman L, Card JP, Enquit LW (1993): Spatiotemporal response of astrocytes, ramified and brain macrophages to central neuronal infection with pseudorabies virus. J Neurosci 13:685-702.
63. Ripoll C, Rebillard G (1997): A simple technique to efficiently dissociate primary neurons from 5 day-old rat cochleas. J Neurosci Methods 73:123-128.
64. Roses AD (1994): Apolipoprotein E affects the rate of Alzheimer diseases expression: Beta amyloid burden is a secondary consequence dependent on ApoE genotype and duration of disease. J Neuropathol Exp Neurol 53:429-437.
65. Russell DW, Berger MS, Miller AD (1994): The effects of human serum and cerebrospinal fluid on retroviral vectors and packaging cell lines. Hum Gene Ther 6:635-641.
66. Shaw JAG, Perry VH, Mellanby J (1994): MHC class II expression by microglia in tetanus toxin-induced experimental epilepsy in the rat. Neuropathol Appl Neurobiol 20:392-398.
67. Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HAR, Haines JL, Pericak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St.George-Hyslop PH (1995): Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375:754-760.
68. Smith M E (1993): Phagocytosis of myelin by microglia in vitro. J Neurosci Res 35:480-487.
69. Smith AD (1994): Protective effect of ApoE epsilon 2 in Alzheimer's disease. Lancet 344:473-474.
70. Stevens A, Bähr M (1993): Origin of macrophages in central nervous tissue. A study using intraperitoneal transplants contained in Millipore diffusion chambers. J Neurol Sci 118:117-122.
71. Streit WJ (1996): The role of microglia in brain injury. Neurotoxicology 17:671-678.
72. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD (1993): Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease. Proc Natl Acad Sci USA 90:1977-1981.
73. Talbot C, Lendon C, Craddock N, Shears S, Morris JC, Goate A (1994): Protection against Alzheimer's disease with ApoE epsilon 2. Lancet 343:1432-1433.
74. Tiret L (1994): ApoE polymorphism and predisposition to coronary heart disease in youths of different European populations. The EARS study. Arterioscler and Thromb 14:1617-1624.
75. Vass K, Lassmann H (1990): Intrathecal application of interferon gamma: Progressive appearance of MHC antigens within the nervous system. Am J Pathol 137:789-800.
76. Walker DG, Kim SU, McGeer PL (1995): Complement and cytokine gene expression in cultures microglia derived from postmortem human brains. J Neurosci Res 40:478-493.
77. Whittemore ER, Korotzer AR, Etebari A, Cotman CW (1993): Carbachol increases intracellular free calcium in cultured rat microglia. Brain Res 621:59-64.
78. Wisniewski T, Castano E, Ghiso J, Frangione B (1993): Cerebrospinal fluid inhibits Alzheimer beta amyloid fibril formation in vitro. Ann Neurol 34:631-633.
79. Yamasaki Y (1995): Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26:676-680.