-
1
-
-
0039234462
-
Subtilisins: Primary structure, chemical and physical properties
-
Academic Press, New York.
-
Markland, F. S. & Smith, E. L. (1971) Subtilisins: primary structure, chemical and physical properties, in The enzymes (Boyer, R. D., ed.), 3rd edn vol. 3, pp. 561-608, Academic Press, New York.
-
(1971)
In the Enzymes (Boyer, R. D., Ed.), 3rd Edn Vol. 3
, pp. 561-608
-
-
Markland, F.S.1
Smith, E.L.2
-
2
-
-
0025998717
-
-
Siezen, R. J., DeVos, W. M., Leunissen, J. A. M. & Dijkstra, B. W. (1991) Homology modelling and protein engineering strategy of subtilases, the family of subtilisin like serine proteinases, Protein Eng. 4, 719-737.
-
(1991)
Homology Modelling and Protein Engineering Strategy of Subtilases, the Family of Subtilisin like Serine Proteinases, Protein Eng.
, vol.4
, pp. 719-737
-
-
Siezen, R.J.1
Devos, W.M.2
Leunissen, J.A.M.3
Dijkstra, B.W.4
-
3
-
-
0023660015
-
Electrostatic effects on modification of charged groups in the active site cleft of subtilisin by protein engineering, J
-
Russell, A. J., Thomas, P. G. & Fersht, A. R. (1987) Electrostatic effects on modification of charged groups in the active site cleft of subtilisin by protein engineering, J. Mol. Biol. 193, 803-813.
-
(1987)
Mol. Biol.
, vol.193
, pp. 803-813
-
-
Russell, A.J.1
Thomas, P.G.2
Fersht, A.R.3
-
4
-
-
0023661636
-
-
Pantoliano, M. W., Ladner, R. C., Bryan, P. N., Rollence, M. L., Wood, J. F. & Poulos, T. L. (1987) Protein engineering of subtilisin BPN': enhanced stabilization through the introduction of two cysteins to form a disulphide bond, Biochemistry 26, 2077-2082.
-
(1987)
Protein Engineering of Subtilisin BPN': Enhanced Stabilization through the Introduction of Two Cysteins to Form a Disulphide Bond, Biochemistry
, vol.26
, pp. 2077-2082
-
-
Pantoliano, M.W.1
Ladner, R.C.2
Bryan, P.N.3
Rollence, M.L.4
Wood, J.F.5
Poulos, T.L.6
-
5
-
-
0023691688
-
-
Pantoliano, M. W., Whitlow, M., Wood, J. F., Rollence, M. L., Finzel, B. C., Gilliland, G. L., Poulos, T. L. & Bryan, P. N. (1988) The engineering of binding affinity at metal ion binding sites for stabilization of proteins: subtilisin as a test case, Biochemistry 27, 8311-8317.
-
(1988)
The Engineering of Binding Affinity at Metal Ion Binding Sites for Stabilization of Proteins: Subtilisin as a Test Case, Biochemistry
, vol.27
, pp. 8311-8317
-
-
Pantoliano, M.W.1
Whitlow, M.2
Wood, J.F.3
Rollence, M.L.4
Finzel, B.C.5
Gilliland, G.L.6
Poulos, T.L.7
Bryan, P.N.8
-
6
-
-
0023783073
-
Subtilisin, an enzyme designed to be engineered, Trends Biochem
-
Wells, J. A. & Esteli, D. A. (1988) Subtilisin, an enzyme designed to be engineered, Trends Biochem. Sei. 13, 291-297.
-
(1988)
Sei.
, vol.13
, pp. 291-297
-
-
Wells, J.A.1
Esteli, D.A.2
-
7
-
-
0024814207
-
-
Carter, P., Nilsson, B., Bumier, J. P., Burdick, D. & Wells, J. A. (1989) Engineering subtilisin BPN' for site-specific proteolysis, Proteins 6, 240-248.
-
(1989)
Engineering Subtilisin BPN' for Site-specific Proteolysis, Proteins
, vol.6
, pp. 240-248
-
-
Carter, P.1
Nilsson, B.2
Bumier, J.P.3
Burdick, D.4
Wells, J.A.5
-
8
-
-
0028168463
-
Cavity mutants of Savinase™ - Crystal structures and differential scanning calorimetry experiments give hints of the function of the buried water molecules in subtilisins, J
-
Pedersen, J. T., OIsen, O. H., Betzel, Gh., Eschenburg, S., Branner, S. & Hastrup, S. (1994) Cavity mutants of Savinase™ - crystal structures and differential scanning calorimetry experiments give hints of the function of the buried water molecules in subtilisins, J. Mol. Biol. 242, 93-202.
-
(1994)
Mol. Biol.
, vol.242
, pp. 93-202
-
-
Pedersen, J.T.1
Oisen, O.H.2
Betzel, G.3
Eschenburg, S.4
Branner, S.5
Hastrup, S.6
-
10
-
-
0000869965
-
Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-c, Acta Cryst
-
Dauter, Z., Betzel, Ch., Genov, N., Pipon, N. & Wilson, K. S. (1991) Complex between the subtilisin from a mesophilic bacterium and the leech inhibitor eglin-c, Acta Cryst. B 47, 707-730.
-
(1991)
B
, vol.47
, pp. 707-730
-
-
Dauter, Z.1
Betzel, Ch.2
Genov, N.3
Pipon, N.4
Wilson, K.S.5
-
11
-
-
0026501813
-
Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 a resolution, J
-
Betzel, Ch., Klupsch, S., Papendorf, G., Hastrup, S., Branner, S. & Wilson, K. S. (1992) Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 A resolution, J. Mol. Biol. 223, 427-445.
-
(1992)
Mol. Biol.
, vol.223
, pp. 427-445
-
-
Betzel, Ch.1
Klupsch, S.2
Papendorf, G.3
Hastrup, S.4
Branner, S.5
Wilson, K.S.6
-
12
-
-
33847444259
-
-
Nedkov, P. T. (1992) Isolation, purification, characterization and application of the bacterial alkaline proteinase subtilisin DY (dissertation thesis), Institute of Organic Chemistry, Bulgarian Academy of Science, Sofia.
-
(1992)
Isolation, Purification, Characterization and Application of the Bacterial Alkaline Proteinase Subtilisin DY (Dissertation Thesis), Institute of Organic Chemistry, Bulgarian Academy of Science, Sofia.
-
-
Nedkov, P.T.1
-
13
-
-
0020445034
-
Chemical, photochemical and spectroscopic characterization of an alkaline proteinase from Bacillus subtilis variant DY, Biochem
-
Genov, N., Shopova, M., Boteva, R., Jori, G. & Ricchelli, F. (1982) Chemical, photochemical and spectroscopic characterization of an alkaline proteinase from Bacillus subtilis variant DY, Biochem. J. 207, 193-200.
-
(1982)
J.
, vol.207
, pp. 193-200
-
-
Genov, N.1
Shopova, M.2
Boteva, R.3
Jori, G.4
Ricchelli, F.5
-
14
-
-
0022040728
-
Determination of the complete amino acid sequence of subtilisin DY and its comparison with the primary structures of the subtilisins BPN′, Carlsberg and Amylosacchariticus, Biol
-
Nedkov, P. T., Oberthür, W. & Braunitzer, G. (1985) Determination of the complete amino acid sequence of subtilisin DY and its comparison with the primary structures of the subtilisins BPN′, Carlsberg and Amylosacchariticus, Biol. Cliem. Hoppe-Seyler 566,421-430.
-
(1985)
Cliem. Hoppe-Seyler
, pp. 421-430
-
-
Nedkov, P.T.1
Oberthür, W.2
Braunitzer, G.3
-
16
-
-
0028902191
-
Stability of subtilisins and related proteinases (subtilases), Int
-
Genov, N., Filippi, B., Dolashka, P., Wilson, K. S. & Betzel, Ch. (1994) Stability of subtilisins and related proteinases (subtilases), Int. J. Peptide Protein Res. 45, 391-400.
-
(1994)
J. Peptide Protein Res.
, vol.45
, pp. 391-400
-
-
Genov, N.1
Filippi, B.2
Dolashka, P.3
Wilson, K.S.4
Betzel, Ch.5
-
17
-
-
0027521836
-
Kinetic characterization of alkaline mesentericopeptidase
-
Dolaschka, P., Genov, N., Ermer, A., Peters, K. & Fittkau, S. (1993) Kinetic characterization of alkaline mesentericopeptidase. Com-parison with serine proteinases from different origins, Int. J. Peptide Protein Res. 42, 560-564.
-
(1993)
Com-parison with Serine Proteinases from Different Origins, Int. J. Peptide Protein Res.
, vol.42
, pp. 560-564
-
-
Dolaschka, P.1
Genov, N.2
Ermer, A.3
Peters, K.4
Fittkau, S.5
-
18
-
-
0024561189
-
Subtilisin DY -kinetic characterization and comparison with related proteinases, Citrr
-
Peters, K., Pauli, D., Helmer, H., Boteva, R. N., Genov, N. & Fittkau, S. (1989) Subtilisin DY -kinetic characterization and comparison with related proteinases, Citrr. Microbiol. 18, 171 -177.
-
(1989)
Microbiol.
, vol.18
, pp. 171-177
-
-
Peters, K.1
Pauli, D.2
Helmer, H.3
Boteva, R.N.4
Genov, N.5
Fittkau, S.6
-
19
-
-
0027461355
-
-
Betzel, Ch., Dauter, Z., Genov, N., Lamzin, V., Navaza, J., Schnebli, H. P., Visanji, M. & Wilson, K. S. (1993) Structure of the proteinase inhibitor eglin-c with hydrolysed reactive center at 2.0 Å resolution, FEES Lett. 317, 185-188.
-
(1993)
Structure of the Proteinase Inhibitor Eglin-c with Hydrolysed Reactive Center
, pp. 185-188
-
-
Betzel, Ch.1
Dauter, Z.2
Genov, N.3
Lamzin, V.4
Navaza, J.5
Schnebli, H.P.6
Visanji, M.7
Wilson, K.S.8
-
20
-
-
0022701771
-
Refined 1.2 a crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c
-
Bode, W., Papamokos, E., Musil, D., Seemueller, U. & Fritz, H. (1986) Refined 1.2 A crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c. Molecular structure of eglin c and its detailed interaction with subtilisin, EMBOJ. 5, 813-818.
-
(1986)
Molecular Structure of Eglin C and Its Detailed Interaction with Subtilisin, EMBOJ.
, vol.5
, pp. 813-818
-
-
Bode, W.1
Papamokos, E.2
Musil, D.3
Seemueller, U.4
Fritz, H.5
-
22
-
-
0027317805
-
Crystallization and preliminary X-ray analysis of subtilisin DY, a natural mutant of subtilisin Carlsberg, Arch
-
Betzel, Ch., Visanji, M., Eschenburg, S., Wilson, K. S., Peters, K., Fittkau, S., Singh, T. P. & Genov, N. (1993) Crystallization and preliminary X-ray analysis of subtilisin DY, a natural mutant of subtilisin Carlsberg, Arch. Biochem. Biophys. 302, 499-502.
-
(1993)
Biochem. Biophys.
, vol.302
, pp. 499-502
-
-
Betzel, Ch.1
Visanji, M.2
Eschenburg, S.3
Wilson, K.S.4
Peters, K.5
Fittkau, S.6
Singh, T.P.7
Genov, N.8
-
24
-
-
84920325457
-
AMORE: An automated package for molecular replacement, Acta Cryst
-
Navaza, J. (1994) AMORE: an automated package for molecular replacement, Acta Cryst. D50, 157-163.
-
(1994)
D
, vol.50
, pp. 157-163
-
-
Navaza, J.1
-
25
-
-
0002595956
-
-
Hendrickson, W. A. & Können, J. H. (1980) Stereochemically restrained crystallographic least-squares refinement of macromolecular structures, in Biomolecitlar structure, function conformation and evolution (Srinivisan, R., ed.) vol. 1, pp. 43-57, Pergamon, Oxford.
-
(1980)
Stereochemically Restrained Crystallographic Least-squares Refinement of Macromolecular Structures, in Biomolecitlar Structure, Function Conformation and Evolution (Srinivisan, R., Ed.)
, vol.1
, pp. 43-57
-
-
Hendrickson, W.A.1
Können, J.H.2
-
26
-
-
84868093436
-
A new least-squares refinement technique based on the fast Fourier transform algorithm, Acta Cryst
-
Agarwal, R. C. (1978) A new least-squares refinement technique based on the fast Fourier transform algorithm, Acta Cryst. A34, 791-809.
-
(1978)
A
, vol.34
, pp. 791-809
-
-
Agarwal, R.C.1
-
27
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography, Acta Cryst
-
Collaborative Computational Project Number 4 (1994) The CCP4 suite: programs for protein crystallography, Acta Cryst. D50, 760-763.
-
(1994)
D
, vol.50
, pp. 760-763
-
-
-
28
-
-
0000356656
-
A graphics model building and refinement system for macromolecules, J
-
Jones, T. A. (1978) A graphics model building and refinement system for macromolecules, J. Appl. Cryst. 11, 268-272.
-
(1978)
Appl. Cryst.
, vol.11
, pp. 268-272
-
-
Jones, T.A.1
-
29
-
-
84893482610
-
A solution for the best rotation to relate two sets of vectors, Acta Cryst
-
Kabsch, W. (1978) A solution for the best rotation to relate two sets of vectors, Acta Cryst. A32, 922-923.
-
(1978)
A
, vol.32
, pp. 922-923
-
-
Kabsch, W.1
-
31
-
-
84944812409
-
Improved Fourier coefficients for maps using phases from partial structures with errors, Acta Cryst
-
Read, R. J. (1986) Improved Fourier coefficients for maps using phases from partial structures with errors, Acta Cryst. A42, 140-149.
-
(1986)
A
, vol.42
, pp. 140-149
-
-
Read, R.J.1
-
33
-
-
0000243829
-
PROCHECK: A program to check the Stereochemical quality of protein structures, J
-
Laskowski, R. A., MacArthur, M. W., Moss, D. S. & Thornton, J. M. (1993) PROCHECK: a program to check the Stereochemical quality of protein structures, J. Appl. Cryst. 26, 283-291.
-
(1993)
Appl. Cryst.
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
34
-
-
0014682668
-
-
Wright, C. S., Alden, R. A. & Kraut, J. (1969) Structure of subtilisin BPN' at 2.5 Å resolution, Nature 221, 235-242.
-
(1969)
Structure of Subtilisin BPN' at
, vol.2
, pp. 235-242
-
-
Wright, C.S.1
Alden, R.A.2
Kraut, J.3
-
35
-
-
0025329212
-
Crystal structure of Thermitase at 1.4 Aresolution
-
Teplyakov, A. V., Kuranova, I. P., Harutyunyan, E. H., Vainshtein, B. K., Frömmel, C., Höhne, W. E. &=WiIson, K. S. W. (1990) Crystal structure of Thermitase at 1.4 Aresolution, J. Mol. Biol. 214,261-219.
-
(1990)
J. Mol. Biol.
, pp. 261-219
-
-
Teplyakov, A.V.1
Kuranova, I.P.2
Harutyunyan, E.H.3
Vainshtein, B.K.4
Frömmel, C.5
Höhne, W.E.6
-
36
-
-
0024191755
-
Three-dimensional structure of proteinase K at 0.15 nm resolution, Ear
-
Betzel, C., Pal, G. P. & Saenger, W. (1988) Three-dimensional structure of proteinase K at 0.15 nm resolution, Ear. J. Biochem. 178, 155-171.
-
(1988)
J. Biochem.
, vol.178
, pp. 155-171
-
-
Betzel, C.1
Pal, G.P.2
Saenger, W.3
-
37
-
-
0024276069
-
Nucleotide sequence of the gene for aqualysin I (a thermophilic alkaline serine protease) of Thennus aqualicus YT-1 and characteristics of the deduced primary structure of the enzyme, £111: J
-
Kwon, S. T., Terada, I., Matsuzawa, H. & Ohta, T. (1988) Nucleotide sequence of the gene for aqualysin I (a thermophilic alkaline serine protease) of Thennus aqualicus YT-1 and characteristics of the deduced primary structure of the enzyme, £111: J. Biochem. 173,491-491.
-
(1988)
Biochem.
, pp. 491-491
-
-
Kwon, S.T.1
Terada, I.2
Matsuzawa, H.3
Ohta, T.4
-
38
-
-
0023643147
-
The high resolution X-ray structure of the complex formed between subtilisin Carlsberg and eglin C, an elastase inhibitor from the leech Hirudo medicinalis, Eur
-
Bode, W., Papamokos, E. & Musil, D. (1987) The high resolution X-ray structure of the complex formed between subtilisin Carlsberg and eglin C, an elastase inhibitor from the leech Hirudo medicinalis, Eur. J. Biochem. 166, 673-692.
-
(1987)
J. Biochem.
, vol.166
, pp. 673-692
-
-
Bode, W.1
Papamokos, E.2
Musil, D.3
-
39
-
-
33847799412
-
Structure and mechanism of chymotrypsin, Accounts Chem
-
Blow, D. M. (1976) Structure and mechanism of chymotrypsin, Accounts Chem. Res. 9, 145-152.
-
(1976)
Res.
, vol.9
, pp. 145-152
-
-
Blow, D.M.1
-
40
-
-
0017324044
-
Serine proteases: Structure and mechanism of catalysis, Anmt
-
Kraut, J. (1977) Serine proteases: structure and mechanism of catalysis, Anmt. Rev. Biochem. 46, 331-358.
-
(1977)
Rev. Biochem.
, vol.46
, pp. 331-358
-
-
Kraut, J.1
-
42
-
-
0000818624
-
Crystal and molecular struc ture of chymotrypsin inhibitor2 from barley-seeds in complex with subtilisin NOVO, Proc
-
McPhalen, C. A., Svendsen, I., Jonassen, I. & James, M. N. G. (1985) Crystal and molecular struc ture of chymotrypsin inhibitor2 from barley-seeds in complex with subtilisin NOVO, Proc. Natl Acad. Sei. USA 82, 7242-7246.
-
(1985)
Natl Acad. Sei. USA
, vol.82
, pp. 7242-7246
-
-
McPhalen, C.A.1
Svendsen, I.2
Jonassen, I.3
James, M.N.G.4
-
43
-
-
0026530977
-
Natural protein proteinase inhibitors and their interaction with proteinases, Eur
-
Bode, W. & Huber, R. (1992) Natural protein proteinase inhibitors and their interaction with proteinases, Eur. J. Biochem. 204,433-451.
-
(1992)
J. Biochem.
, pp. 433-451
-
-
Bode, W.1
Huber, R.2
-
45
-
-
0023691688
-
The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: Subtilisin as a test case
-
Pantoliano, M. W., Whitlow, M, Wood, J. F., Rollence, M L., Finzel, B. C., Gilliland, G. L., Poulos, T. L. & Bryan, P. N. (1988) The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case, Biochemistry 27, 8311-8317.
-
(1988)
Biochemistry
, vol.27
, pp. 8311-8317
-
-
Pantoliano, M.W.1
Whitlow, M.2
Wood, J.F.3
Rollence, M.L.4
Finzel, B.C.5
Gilliland, G.L.6
Poulos, T.L.7
Bryan, P.N.8
-
47
-
-
0017075046
-
The role of bound calcium ions in thermostable, proteolytic enzymes
-
Voordouw, G., Milo, C. & Roche, R. S. (1976). The role of bound calcium ions in thermostable, proteolytic enzymes. Separation of intrinsic and calcium ion contributions to the kinetic thermal stability, Biochemistry 15, 3716-3724.
-
(1976)
Separation of Intrinsic and Calcium Ion Contributions to the Kinetic Thermal Stability, Biochemistry
, vol.15
, pp. 3716-3724
-
-
Voordouw, G.1
Milo, C.2
Roche, R.S.3
-
48
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures, J
-
Kraulis, P. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures, J. Appl. Cryst. 24, 946-950.
-
(1991)
Appl. Cryst.
, vol.24
, pp. 946-950
-
-
Kraulis, P.1
-
49
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models, Acta Cryst
-
Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. (1991) Improved methods for building protein models in electron density maps and the location of errors in these models, Acta Cryst. A47, 110-119.
-
(1991)
A
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.-Y.2
Cowan, S.W.3
Kjeldgaard, M.4
|