Differences in cerebral activation during smooth pursuit and saccadic eye movements using positron-emission tomography

Biological Psychiatry

Volumn 44, Issue 8, 1998, Pages 685-689

  O'Driscoll, Gillian A ^a   Strakowski, Stephen M ^b   Alpert, Nathaniel M ^c   Matthysse, Steven W ^d   Rauch, Scott L ^c   Levy, Deborah L ^d   Holzman, Philip S ^d,e  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MCLEAN HOSPITAL   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

Frontal lobe; Positron emission tomography; Saccades; Schizophrenia; Smooth pursuit

Indexed keywords

ADULT; ARTICLE; EYE MOVEMENT; FRONTAL LOBE; HUMAN; HUMAN EXPERIMENT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SCHIZOPHRENIA; TEMPORAL CORTEX;

ADOLESCENT; ADULT; BRAIN; CARBON RADIOISOTOPES; HUMANS; MALE; MIDDLE AGED; PURSUIT, SMOOTH; SACCADES; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032532507     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(98)00047-X     Document Type: Article

References (33)

1. Alpert N.M., Berdichevsky D., Weise S., Tang J., Rauch S.L. Stereotactic transformation of PET scans by nonlinear least squares. Uemura K., Lassen N.A., Jones T., Kanno I. Quantification of Brain Function Tracer Kinetics and Image Analysis in Brain PET . 1993;459-463 Elsevier, Amsterdam.
2. Anderson T.J., Jenkins I.H., Hawken M., Frackowiak R.S.J., Kennard C., Brooks D.J. Cortical control of saccades and fixation in man A PET scan study . Brain. 117:1994;1073-1084.
3. Barton J.J., Simpson T., Kiriakopoulos E., Stewart C., Crawley A., Guthrie B., et al. Functional MRI of lateral occipitotemporal cortex during pursuit and motion perception. Ann Neurol. 40:1996;387-398.
4. Benitez J.T. Eye tracking and optokinetic tests. Diagnostic significance in peripheral and central vestibular disorders. Laryngoscope. 80:1970;834-848.
5. Colby C.L., Zeffiro T. Cortical activation in humans during visual and oculomotor processing measured by positron emission tomography (PET). Soc Neurosci Abstr. 16:1990;621.
6. Corbetta M., Meizin F.M., Shulman G.L., Peterson S.E. A PET study of visuospatial attention. J Neurosci. 13:1993;1202-1226.
7. Diefendorf A.R., Dodge R. An experimental study of the ocular reactions of the insane from photographic records. Brain. 31:1908;451-489.
8. Friston K., Frith C., Liddle P., Frackowiak R. Comparing functional (PET) images The assessment of significance . J Cereb Blood Flow Metab. 11:1991;690-699.
9. Holzman P.S., Proctor L.R., Levy D.L., Yasillo N.J., Meltzer H.Y., Hurt S.W. Eye-tracking dysfunctions in schizophrenic patients and their relatives. Arch Gen Psychiatry. 31:1974;143-151.
10. Iacono W.G., Lykken D.T. Eye tracking and psychopathology New procedures applied to a sample of normal monozygotic twins . Arch Gen Psychiatry. 36:1979;1361-1369.
11. Kosslyn S.M., Alpert N.M., Thompson W.L., Maljkovic V., Weise S.B., Chabris C.F., et al. Visual mental imagery activates topographically organized visual cortex PET investigations . J Cogn Neurosci. 5:1993;263-287.
12. 2 build-up technique to measure regional cerebral blood flow and volume of distribution of water. J Cereb Blood Flow Metab. 9:1989;461-470.
13. Leigh J.R., Zee D.S. The Neurology of Eye Movements. 1991;FA Davis, Philadelphia.
14. Levin S. Frontal lobe dysfunctions in schizophrenia-I. Eye movement impairments. J Psychiatr Res. 18:1984;27-55.
15. Levy D.L., Holzman P.S., Matthysse S., Mendell N.R. Eye tracking dysfunction and schizophrenia A critical perspective . Schizophr Bull. 19:1993;461-536.
16. MacAvoy M., Gottlieb J.P., Bruce C.J. Smooth pursuit eye movement representation in the frontal eye field. Cereb Cortex. 1:1991;95-102.
17. Matthysse S., Holzman P.S., Lange K. The genetic transmission of schizophrenia Application of Mendelian latent structure analysis to eye tracking dysfunctions in schizophrenia and affective disorder . J Psychiatr Res. 20:1986;57-67.
18. Morrow M.J., Sharpe J.S. Retinotopic and directional deficits of smooth pursuit initiation after posterior cerebral hemispheric lesions. Neurology. 43:1993;595-603.
19. Morrow M.J., Sharpe J. Deficits of smooth-pursuit eye movement after unilateral frontal lobe lesions. Ann Neurol. 37:1995;443-451.
20. Newsome W.T., Wurtz R.H., Komatsu H. Relation of cortical areas MT and MST to pursuit eye movements. II. Differentiation of retinal from extraretinal inputs. J Neurophysiol. 60:1988;604-620.
21. O'Driscoll G.A., Strakowski S., Alpert N., Holzman P.S. A PET study of differential patterns of brain activation in SPEM vs. saccadic eye movements. Schizophr Res. 9:1993;205.
22. O'Driscoll G.A., Alpert N., Matthysse S.M., Levy D., Rauch S., Holzman P.S. Functional neuroanatomy of antisaccade eye movements investigated with positron emission tomography. Proc Natl Acad Sci USA. 92:1995;925-929.
23. O'Driscoll GA, Benkelfat C, Florencio PS, Wolff AL, Grivell J, Joober J, et al (in press): The functional relevance of superior parietal activation during smooth pursuit. Neurolmage.
24. Ross D.E., Thaker G.K., Holcomb H.H., Cascella N.G., Medoff D.R., Tamminga C.A. Abnormal smooth pursuit eye movements in schizophrenic patients are associated with cerebral glucose metabolism in oculomotor regions. Psychiatry Res. 58:1995;53-67.
25. Rota-Kops E., Herzog H., Schmid A., Holte S., Feinendegen L.E. Performance characteristics of an eight-ring whole body PET scanner. J Comp Asst Tomogr. 14:1990;437-445.
26. Roy-Byrne P., Radant A., Wingerson D., Cowley D.S. Human oculomotor function Reliability and diurnal variation . Biol Psychiatry. 38:1995;92-97.
27. Shagass C., Amadeo M., Overton D.A. Eye-tracking performance in psychiatric patients. Biol Psychiatry. 9:1974;245-260.
28. Spitzer R.L., Williams J.B.W., Gibbon M., First M.B. The Structured Clinical Interview for DSM-III-R. 1990;New York State Psychiatric Institute, New York.
29. Sweeney J., Mintun M.A., Kwee S., Brown D.L., Rosenberg D.R., Carl J.R. Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. J Neurophsyiol. 75:1996;454-468.
30. Talairach J., Szikla Z. Atlas of Stereotactic Anatomy of the Telencephelon. 1967;Masson & Cie, Paris.
31. Talairach J., Tournoux P. Co-Planar Stereotactic Atlas of the Human Brain. 1988;Thieme, Stuttgart.
32. Tootell R.B., Reppas J.B., Kwong K.K., Malach R., Born R.T., Brady T.J., et al. Functional analysis of human MT and related visual cortical areas using magnetic resonance imaging. J Neurosci. 15:1995;3215-3230.
33. Watson J.D.G., Myers R., Frackowiak R.S.J., Hajnal J.V., Wood R.P., Mazziotta J.C., et al. Area V5 of the human brain Evidence from a combined study using positron emission tomography and magnetic resonance imaging . Cereb Cortex. 3:1993;79-94.