Development of peptide-selected CD8 T cells in fetal thymic organ culture occurs via the conventional pathway

Journal of Immunology

Volumn 161, Issue 8, 1998, Pages 3896-3901

  Hogquist, Kristin A ^a   Bonnevier, Jody L ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; FETUS; FLOW CYTOMETRY; LYMPHOCYTE DIFFERENTIATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; THYMUS;

ANIMALS; ANTIGENS, CD8; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; FEMALE; LIGANDS; MICE; PEPTIDES; PREGNANCY; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; THYMUS GLAND;

EID: 0032531985     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1995. Positive selection of thymocytes. Annu. Rev. Immunol. 13:93.
2. Jenkinson, E. J., and J. J. Owen. 1990. T-cell differentiation in thymus organ cultures. Semin. Immunol. 2:51.
3. Ashton-Rickardt, P. G., A. Bandeira, J. R. Delaney, L. Van Kaer, H.-P. Pircher, R. M. Zinkernagel, and S. Tonegawa. 1994. Evidence for a differential avidity model of T cell selection in the thymus. Cell 76:651.
4. Sebzda, E., V. A. Wallace, J. Mayer, R. S. M. Yeung, T. W. Mak, and P. S. Ohashi. 1994. Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 263:1615.
5. + T cells. Immunity 3:79.
6. Hogquist, K. A., S. C. Jameson, W. R. Heath, J. L. Howard, M. J. Bevan, and F. R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell 76:17.
7. Pawlowski, T. J., M. D. Singleton, D. Y. Loh, R. Nerg, and U. D. Staerz. 1996. Permissive recognition during positive selection. Eur. J. Immunol. 26:851.
8. Teh, H. S., H. Kishi, B. Scott, P. Borgulya, and H. von Boehmer. 1990. Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice. Dev. Immunol. 1:1.
9. Borgulya, P., H. Kishi, Y. Uematsu, and H. von Boehmer. 1992. Exclusion and inclusion of α and β T cell receptor alleles. Cell 69:529.
10. Levelt, C. N., and K. Eichmann. 1995. Receptors and signal in early thymic selection. Immunity 3:667.
11. + T cells from a common precursor. Semin. Immunol. 9:171.
12. Bruno, L., H. J. Fehling, and H. von Boehmer. 1996. The αβ T cell receptor can replace the γδ receptor in the development of γδ lineage cells. Immunity 5:343.
13. von Boehmer, H., J. Kirberg, and B. Rocha. 1991. An unusual lineage of α/β T cells that contains autoreactive cells. J. Exp. Med. 174:1001.
14. Haas, W., P. Pereira, and S. Tonegawa. 1993. γ/δ cells. Annu. Rev. Immunol. 11:637.
15. MacDonald, H. R., M. Schreyer, R. C. Howe and C. Bron. 1990. Selective expression of CD8α (Ly-2) subunit on activated thymic γ/δ cells. Eur. J. Immunol. 20:927.
16. Kisielow, P., and H. von Boehmer. 1995. Development and selection of T cells: facts and puzzles. Adv. Immunol. 58:87.
17. Brandle, D., S. Muller, C. Muller, H. Hengartner, and H. Pircher. 1994. Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur. J. Immunol. 24:145.
18. + T cells. Science 248:1227.
19. low thymocytes in vivo. Science 250: 1720.
20. Schumacher, T. N., M. T. Heemels, J. J. Neefjes, W. M. Kast, C. J. Melief, and H. L. Ploegh. 1990. Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell 62:563.
21. lck. EMBO J. 11:4877.
22. Girao, C., Q. Hu, J. Sun, and P. G. Ashton-Rickardt. 1997. Limits to the differential affinity model of T cell selection in the thymus. J. Immunol. 159:4205.
23. Hogquist, K. A., A. J. Tomlinson, W. C. Kieper, M. A. McGargill, M. C. Hart, S. Naylor, and S. C. Jameson. 1997. Identification of a naturally occurring ligand for thymic positive selection. Immunity 6:389.
24. Alam, S. M., P. J. Travers, J. L. Wung, W. Nasholds, S. Redpath, S. C. Jameson, and N. R. J. Gascoigne. 1996. T-cell receptor affinity and thymocyte positive selection. Nature 381:616.
25. Jameson, S. C., F. R. Carbone, and M. J. Bevan. 1993. Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells. J. Exp. Med. 177:1541.
26. Mertsching, E., A. Wilson, H. R. MacDonald, and R. Ceredig. 1997. T cell receptor α gene rearrangement and transcription in adult thymic γδ cells. Eur. J. Immunol. 27:389.
27. + thymocytes in vitro. J. Exp. Med. 179:2027.
28. Sebzda, E., T. M. Kundig, C. T. Thomson, K. Aoki, S.-Y. Mak, J. P. Mayer, T. Zamborelli, S. G. Nathenson, and P. S. Ohashi. 1996. Mature T cell reactivity altered by peptide agonist that induces positive selection. J. Exp. Med. 183:1093.
29. Barnden, M. J. N, W. R. Heath, and F. R. Carbone. 1997. Down-modulation of CD8 β-chain in response to an altered peptide ligand enables developing thymocytes to escape negative selection. Cell. Immunol. 175:111.
30. - coreceptor expression. Int. Immunol. 9:1527.
31. Zamoyska, R. 1994. The CD8 coreceptor revisited: one chain good, two chains better. Immunity 1:243.
32. Kawabata, K., M. Nagasawa, T. Morio, H. Okawa, and J. Yata. 1996. Decreased α/β heterodimer among CD8 molecules of peripheral blood T cells in Wiskott-Aldrich syndrome. Clin. Immunol. Immunopathol. 81:129.