Protective effects of the thiophosphate amifostine (WR 2721) and a lazaroid (U83836E) on lipid peroxidation in endothelial cells during hypoxia/reoxygenation

Biochemical Pharmacology

Volumn 56, Issue 8, 1998, Pages 945-954

  Mertsch, Katharina ^a   Grune, Tilman ^b   Kunstmann, Steffen ^b   Wiesner, Burkhard ^a   Ladhoff, Axel M ^b   Siems, Werner G ^c   Haseloff, Reiner F ^a   Blasig, Ingolf E ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c Herzog Julius Klinik GmbH & Co KG   (Germany)

Author keywords

Endothelial cells; Hypoxia and reoxygenation; Lazaroid U83836E; Lipid peroxidation; Radical scavengers; Thiophosphate WR 2721

Indexed keywords

2 (3 AMINOPROPYLAMINO)ETHANETHIOL; 2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; 21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; ALPHA TOCOPHEROL; AMIFOSTINE; LAZAROID; REACTIVE OXYGEN METABOLITE; TROLOX C;

ANIMAL CELL; AORTA; ARTICLE; CATTLE; CELL PROTECTION; CELL VIABILITY; CYTOTOXICITY; DRUG EFFECT; ELECTRON SPIN RESONANCE; ENDOTHELIUM CELL; HYPOXIA; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION;

AMIFOSTINE; ANIMALS; ANTIOXIDANTS; AORTA; CATTLE; CELL HYPOXIA; CELL SURVIVAL; CHROMANS; CYTOPROTECTION; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; LIPID PEROXIDATION; OXYGEN; PIPERAZINES;

EID: 0032531939     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00103-8     Document Type: Article

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