Identification of Asp95 as the site of succinimide formation in recombinant human glial cell line-derived neurotrophic factor

Archives of Biochemistry and Biophysics

Volumn 358, Issue 2, 1998, Pages 377-384

  Hui, John O ^a   Chow, David T ^a   Markell, David ^a   Robinson, John H ^a   Katta, Viswanatham ^a   Nixon, Lori ^a   Chang, Byeong S ^a   Rohde, Michael F ^a   Haniu, Mitsuru ^a  

^a AMGEN INC   (United States)

Author keywords

Glial cell line derived neurotrophic factor; HPLC; Isoaspartate; Mass spectrometry; Succinimide

Indexed keywords

ASPARTIC ACID; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LYSINE; RECOMBINANT PROTEIN; SUCCINIMIDE; AMINO ACID; GDNF PROTEIN, HUMAN; NERVE GROWTH FACTOR; NERVE PROTEIN; PEPTIDE FRAGMENT; SUCCINIMIDE DERIVATIVE;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HUMAN; HYDROLYSIS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ASPARTIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS; SUCCINIMIDES;

EID: 0032531424     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1998.0884     Document Type: Article

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