Role of class-II major histocompatibility complex (MHC)-antigen-positive donor leukocytes in transfusion-induced alloimmunization to donor class-I MHC antigens

Blood

Volumn 92, Issue 2, 1998, Pages 690-694

  Kao, K J ^a,b   Del Rosario, M L U ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALLOIMMUNIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; HUMORAL IMMUNITY; IMMUNOGENICITY; LEUKOCYTE TRANSFUSION; MAJOR HISTOCOMPATIBILITY COMPLEX; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032528415     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.2.690.414k12_690_694     Document Type: Article

References (13)

1. Kao KJ, Scornik JC, Riley WJ, McQueen CF: Association between HLA phenotype and HLA concentration in plasma or platelets. Human Immunol 21:115, 1988
2. Pellegrino MA, Indiveri F, Fagiolo U, Antonello A, Ferrone S: Immunogenicity of serum HLA antigens in allogeneic combinations. Transplantation 22:530, 1982
3. Batchelor JR, Welsh KJ, Burgos H: Transplantation antigens per se are poor immunogens within a species. Nature 273:54, 1978
4. Claas FHJ, Smeenk RJT, van Steenburugge GH, Eernisse JG: Alloiminimization against the MHC antigens after platelet transfusion is due to contaminating leukocytes in the platelet suspension. Exp Hematol 9:84, 1981
5. Meryman HT: Transfusion-induced alloimmunization and immunosuppression and the effects of leukocyte depletion. Transfusion Med Rev III: 180, 1989
6. Slichter SJ, Deeg HJ. Kennedy MS: Prevention of platelet alloimmunization in dogs with systemic cyclosporine and by UV-irradiated or cyclosporine-loading of donor platelets. Blood 69:414, 1987
7. Kao KJ: Effects of leukocyte depletion and UVB irradiation on alloantigenicity of major histocompatibility complex antigens in platelet concentrates: A comparative study. Blood 80:2931, 1992
8. TRAP Trial Study Group: Leukocyte-reduction and UV-B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusion. N Eng J Med 337:186, 1997
9. Faustman D, Hauptfeld V, Lacy P, Davie J: Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to IA determinants. Proc Natl Acad Sci USA 78:5156, 1981
10. Bordin JO, Heddle NM, Blajchman MA: Biologic effects of leukocytes present in transfused cellular blood products. Blood 84: 1703, 1994
11. Gosgrove D, Gray D, Dierich A, Kaufman J, Lemeur M, Benoist C, Mathis D: Mice lacking MHC Class II molecules. Cell 66:1051, 1991
12. Grana NH, Kao KJ: Use of 8-methoxypsoralen and ultraviolet-A pretreated platelet concentrates to prevent alloimmunization against class I major histocompatibility antigens. Blood 77:2530, 1991
13. Bang A, Speck ER, Blanchette VS, Freedman J, Semple JW: Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase. Blood 88:2959, 1996