Response of quiescent and total tumor cells in solid tumors to neutrons with various cadmium ratios

International Journal of Radiation Oncology Biology Physics

Volumn 41, Issue 5, 1998, Pages 1163-1170

  Masunaga, Shin Ichiro ^a   Ono, Koji ^a   Sakurai, Yoshinori ^a   Takagaki, Masao ^a   Kobayashi, Toru ^a   Suzuki, Minoru ^a   Kinashi, Yuko ^a   Akaboshi, Mitsuhiko ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Boronophenylalanine; Cadmium ratio; Micronucleus; Neutron capture reaction; Quiescent cell; SCC VII tumor; Sodium borocaptate

Indexed keywords

CADMIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CONTROL; CELL POPULATION; GAMMA RADIATION; IMMUNOFLUORESCENCE; MICRONUCLEUS; MOUSE; NEUTRON; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; SOLID TUMOR; TISSUE REACTION; TUMOR DIAGNOSIS; TUMOR GROWTH;

ANIMALS; BOROHYDRIDES; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BROMODEOXYURIDINE; CADMIUM RADIOISOTOPES; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENERGY TRANSFER; FEMALE; GAMMA RAYS; MICE; MICE, INBRED C3H; MICRONUCLEUS TESTS; PHENYLALANINE; RELATIVE BIOLOGICAL EFFECTIVENESS; SULFHYDRYL COMPOUNDS;

EID: 0032528222     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00149-7     Document Type: Article

References (26)

1. Barth R.F., Soloway A.H., Brugger R.M. Boron neutron capture therapy of brain tumors Past history, current status, and future potential . Cancer Invest. 14:1996;534-550.
2. Jackson R.C. The problem of the quiescent cancer cell. Enzyme Regul. 29:1989;27-46.
3. Masunaga S., Ono K., Abe M. Potentially lethal damage repair by quiescent cells in murine solid tumors. Int. J. Radiat. Oncol. Biol. Phys. 22:1992;973-978.
4. Kanda K. An overview Radiation sources, beam quality, dosimetry and spectroscopy in neutron capture therapy . Strahlenther. Onkol. 165:1989;67-69.
5. Kobayashi T., Kanda K., Fujita Y., Sakurai Y., Ono K. The upgrade of the heavy water facility of the Kyoto University Reactor for neutron capture therapy. Larsson B., Crawford J., Weinreich R. Advances in Neutron Capture Therapy. I:1997;321-325 Elsevier Science, Amsterdam, The Netherlands.
6. Sakurai Y., Kobayashi T., Kanda K., Ono K. The irradiation characteristics of the upgraded heavy water facility of the Kyoto University Reactor. Larsson B., Crawford J., Weinreich R. Advances in Neutron Capture Therapy. I:1997;316-320 Elsevier Science, Amsterdam, The Netherlands.
7. Caswell R.S., Coyne J.J., Randolph M.L. Kerma factors for neutron energies below 30 MeV. Radiat. Res. 83:1980;217-254.
8. Snyder W.S., Cook M.J., Nasset E.S., Karhausen L.R., Parry Howells G., Tipton I.H. Gross and elemental content of reference man. Snyder W.S. Report of the Task Group on Reference Man. 1975;273-324 Pergamon Press, Oxford, UK.
9. 10B concentrations and absorbed dose estimations in human malignant melanoma treated by BNCT. Strahlenther. Onkol. 165:1989;104-106.
10. Fenech M., Morley A. A solution to the kinetic problem in the micronucleus assay. Cytobios. 43:1985;233-246.
11. Ono K., Wandl E.O., Tsutsui K., Sasai K., Abe M. The correlation between cell survival curve and dose response curve of micronucleus (MN) frequency. Strahlenther. Onkol. 165:1989;824-827.
12. Mitchell J., Morstyn G., Russo A., Kinsella T., Fornance A., McPherson S., Glatstein E. Differing sensitivity to fluorescent light in Chinese hamster cells containing equally incorporated quantities of BUdR versus IUdR. Int. J. Radiat. Oncol. Biol. Phys. 10:1984;1447-1451.
13. Midander J., Revesz L. The frequency of micronucleus as a measure of cell survival in irradiated cell populations. Int. J. Radiat. Biol. 38:1980;237-242.
14. Peters L.J., Brock W.A., Johnson T., Meyn R.E., Tofilon P.J., Milas L. Potential methods for predicting tumor radiocurability. Int. J. Radiat. Oncol. Biol. Phys. 12:1986;459-467.
15. Roberts W.A., Morgan G.A., Holt P.D. A critical comparison of the micronucleus yield from high and low LET irradiation of plateau-phase cell populations. Mutat. Res. 160:1986;237-242.
16. Brock W.A., Williams M. Kinetics of micronucleus expression in synchronized irradiated Chinese hamster ovary cells. Cell Tissue Kinet. 18:1985;247-254.
17. Ono K., Masunaga S., Kinashi Y., Takagaki M., Akaboshi M., Kobayashi T., Akuta K. Radiobiological evidence suggesting heterogeneous microdistribution of boron compounds in tumors Its relation to quiescent cell population and tumor cure in neutron capture therapy . Int. J. Radiat. Oncol. Biol. Phys. 34:1996;1081-1086.
18. Wambersie A., Bewley D.K., Lalanne C.M. Prospects for the application of fast neutrons in cancer therapy. Radiobiological bases and survey of the clinical data. Bull. Cancer Paris. 73:1986;546-561.
19. Masunaga S., Ono K., Abe M. The detection and modification of the hypoxic fraction in quiescent cell populations in murine solid tumors. Br. J. Radiol. 66:1993;918-926.
20. Masunaga S., Ono K., Akuta K., Akaboshi M., Ando K., Koike S. The response of quiescent cell populations in murine solid tumors to irradiation with fast neutrons. Acta Oncol. 33:1994;813-817.
21. Aghamohammadi S.Z., Goodhead D.T., Savage J.R. Production of chromosome aberrations, micronuclei, and sister-chromatid exchanges by 24-keV epithermal neutrons in human G0 lymphocytes. Mutat. Res. 211:1989;225-230.
22. Mill A.J., Morgan G.R., Newman S.M. Cell survival measurements in an argon, aluminium and sulphur filtered neutron beam A comparison with 24 keV neutrons and relevance to boron neutron capture therapy . Br. J. Radiol. 67:1994;1008-1016.
23. Ujeno Y. Physical modification of thermal neutron-induced biological effects. Sugahara T. Modification of Radiosensitivity in Cancer Treatment. 1984;477-486 Academic Press, Tokyo.
24. Utsumi H. The radiation biology of boron neutron capture therapy. Nucl. Sci. Appl. 4:1991;325-333.
25. Wallen C.A., Ridinger D.N., Dethlefsen L.A. Heterogeneity of X-ray cytotoxicity in proliferating and quiescent murine mammary carcinoma cells. Cancer Res. 45:1985;3064-3069.
26. Takagaki M., Oda Y., Koda Y., Kikuchi H., Ono K. Effectiveness of borocaptate sodium for boron neutron capture therapy in malignant brain tumors. Mishima Y. Cancer Neutron Capture Therapy. 1996;571-578 Plenum, New York.