Stability of somatropin stored in plastic syringes for 28 days

American Journal of Health-System Pharmacy

Volumn 55, Issue 14, 1998, Pages 1508-1511

  Ray, Lisa R ^a   Chen, Dennis A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Concentration; Hormones; Incompatibilities; Metacresol; Plastics; Polypropylene; Pr ecipitation; Preservatives; Propylene ethylene copolymer; Somatropin; Stability; Storage; Syringes; Turbidity

Indexed keywords

COPOLYMER; ETHYLENE; GLASS; HUMAN GROWTH HORMONE; META CRESOL; POLYPROPYLENE; PROPYLENE;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG POTENCY; DRUG PURITY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SYRINGE; TURBIDITY;

EID: 0032527822     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/55.14.1508     Document Type: Article

References (5)

1. Humatrope package insert. Indianapolis, IN: Eli Lilly and Company; 1996 Jun.
2. Riggin R, Shaar C, Dorulla G et al. High-performance size-exclusion chromatographic determination of the potency of biosynthetic human growth hormone product. J Chromatogr. 1988; 435:307-18.
3. Riggin R, Dorulla G, Miner D. A reversed-phase high-performance liquid chromatography method for characterization of biosynthetic human growth hormone. Anal Chem. 1987; 167:199-209.
4. The United States pharmacopeia, 23rd rev., and The national formulary, 18th ed. Rockville, MD: United States Pharmacopeial Convention; 1994:1681-6.
5. Tarr B, Campbell R, Workman T. Stability and sterility of biosynthetic human insulin stored in plastic insulin syringes for 28 days. Am J Hosp Pharm. 1991; 48:2631-4.